Search Results - "Nagata, Yoshinori"
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Effect of a centrally active angiotensin-converting enzyme inhibitor, perindopril, on cognitive performance in a mouse model of Alzheimer's disease
Published in Brain research (17-09-2010)“…Abstract Angiotensin-converting enzyme (ACE) inhibitors have clinically been widely used as anti-hypertensive agents. In the present study, we compared the…”
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Journal Article -
2
Significant effect of the posterior tibial slope and medial/lateral ligament balance on knee flexion in total knee arthroplasty
Published in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA (01-12-2013)“…Purpose The intra-operative femorotibial joint gap and ligament balance, the predictors affecting these gaps and their balances, as well as the postoperative…”
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3
Safety, Tolerability, and Pharmacokinetics of the Novel Adenosine A2A Antagonist/Inverse Agonist KW‐6356 Following Single and Multiple Oral Administration in Healthy Volunteers
Published in Clinical pharmacology in drug development (01-08-2023)“…KW‐6356 is an adenosine A2A receptor–selective antagonist and inverse agonist. We conducted 2 studies: study 6356‐001 (no NCT number), a randomized,…”
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Journal Article -
4
Effect of a centrally active angiotensin converting enzyme inhibitor, perindopril, on cognitive performance in chronic cerebral hypo-perfusion rats
Published in Brain research (03-11-2011)“…Abstract We have previously demonstrated that perindopril, an angiotensin-converting enzyme (ACE) inhibitor, ameliorated the cognitive deficits in Alzheimer's…”
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Journal Article -
5
Assessment of CYP‐Mediated Drug Interactions for Evocalcet, a New Calcimimetic Agent, Based on In Vitro Investigations and a Cocktail Study in Humans
Published in Clinical and translational science (01-01-2019)“…Evocalcet is a novel calcimimetic agent for the treatment of secondary hyperparathyroidism (SHPT). This study evaluated the effects of evocalcet on inhibition…”
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6
Expression and functional characterization of rat organic anion transporter 3 (rOat3) in the choroid plexus
Published in Molecular pharmacology (01-05-2002)“…We reported previously that an efficient efflux system for benzylpenicillin (PCG) is located on the choroid plexus (CP). In this study, we investigated the…”
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P-glycoprotein Limits the Brain Penetration of Olopatadine Hydrochloride, H1-Receptor Antagonist
Published in DRUG METABOLISM AND PHARMACOKINETICS (01-01-2008)“…Olopatadine, a new second-generation antihistamine, is widely used in the treatment of allergic disorders. The low levels of histamine H1 receptor occupancy in…”
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The Intestinal First-pass Metabolism of Substrates of CYP3A4 and P-glycoprotein -Quantitative Analysis Based on Information from the Literature
Published in DRUG METABOLISM AND PHARMACOKINETICS (2003)“…It is suggested that the bioavailability of CYP3A4 substrates might be low due to first-pass metabolism in the small intestine, and it is possible that…”
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Journal Article -
9
CARRIER-MEDIATED UPTAKE OF H2-RECEPTOR ANTAGONISTS BY THE RAT CHOROID PLEXUS: INVOLVEMENT OF RAT ORGANIC ANION TRANSPORTER 3
Published in Drug metabolism and disposition (01-09-2004)“…The choroid plexus (CP) acts as a site for the elimination of xenobiotic organic compounds from the cerebrospinal fluid (CSF). The purpose of the present study…”
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Journal Article -
10
Physical education class can improve acute inhibitory control in elementary school students
Published in Motriz : Revista de Educação Física. Unesp (2019)“…Abstract Aim: The aim of the study was to analyze the impact of a based-team sports physical education class on inhibitory control of elementary school…”
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Journal Article -
11
Involvement of rat organic anion transporter 3 in the uptake of an organic herbicide, 2,4-dichlorophenoxyacetate, by the isolated rat choroid plexus
Published in Journal of pharmaceutical sciences (01-11-2004)“…2,4-Dichlorophenoxyacetic acid (2,4-D) is an anionic herbicide. The purpose of the present study is to examine whether organic anion transporter 3 (Oat3;…”
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Journal Article -
12
Safety, Tolerability, and Pharmacokinetics of the Novel Adenosine A 2A Antagonist/Inverse Agonist KW-6356 Following Single and Multiple Oral Administration in Healthy Volunteers
Published in Clinical pharmacology in drug development (01-08-2023)“…KW-6356 is an adenosine A receptor-selective antagonist and inverse agonist. We conducted 2 studies: study 6356-001 (no NCT number), a randomized,…”
Get full text
Journal Article -
13
Dislocation of the shoulder joint with ipsilateral humeral shaft fracture: two case reports
Published in Archives of orthopaedic and trauma surgery (01-10-2006)“…A combination of the shaft fracture of the humerus with shoulder dislocation is a rarely documented injury. Moreover, few reports describe a long-term outcome…”
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Journal Article -
14
CARRIER-MEDIATED UPTAKE OF H sub(2)-RECEPTOR ANTAGONISTS BY THE RAT CHOROID PLEXUS: INVOLVEMENT OF RAT ORGANIC ANION TRANSPORTER 3
Published in Drug metabolism and disposition (01-09-2004)“…The choroid plexus (CP) acts as a site for the elimination of xenobiotic organic compounds from the cerebrospinal fluid (CSF). The purpose of the present study…”
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Journal Article -
15
Expression and functional involvement of organic anion transporting polypeptide subtype 3 (Slc21a7) in rat choroid plexus
Published in Pharmaceutical research (01-05-2003)“…It has been shown that transport(s) are involved in the uptake of estradiol 17beta glucuronide (E217betaG) by the choroid plexus (CP). The purpose of this…”
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Journal Article -
16
Highly Efficient Digital Mobile Communications with a Linear Modulation Method
Published in IEEE journal on selected areas in communications (01-06-1987)“…Although linear modulation methods can achieve high spectrum efficiency, very little attention has been directed to their use in mobile radio systems. This is…”
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17
The Intestinal First-pass Metabolism of Substrates of CYP3A4 and P-glycoprotei—Quantitative Analysis Based on Information from the Literature
Published in Drug metabolism and pharmacokinetics (2003)“…It is suggested that the bioavailability of CYP3A4 substrates might be low due to first-pass metabolism in the small intestine, and it is possible that…”
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Journal Article -
18
Development of underwater robot using Macro Fiber Composite
Published in 2008 IEEE/ASME International Conference on Advanced Intelligent Mechatronics (01-07-2008)“…We developed several underwater robots by using macro fiber composite(MFC), a new type of piezo-electric actuator with the merits of being soft and capable of…”
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Conference Proceeding -
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Development of underwater robots using piezoelectric fiber composite
Published in 2009 IEEE International Conference on Robotics and Automation (01-05-2009)“…Underwater robot using piezoelectric fiber composite with the merits of being soft and capable of large displacement, is proposed in this paper. By pasting the…”
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Conference Proceeding -
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Analysis for spectrum efficiency in single cell trunked and cellular mobile radio
Published in IEEE transactions on vehicular technology (01-08-1987)“…Spectrum efficiencies for single-cell trunked and cellular mobile radio systems are analyzed, taking into consideration fading circumstances and call blocking…”
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