Search Results - "Nagasawa, Tomohiro"

Stereoselective total synthesis of amicoumacin C by Suzuki, Tomomi, Nagasawa, Tomohiro, Enomoto, Masaru, Kuwahara, Shigefumi

“…The enantio- and diastereoselective total synthesis of amicoumacin C was achieved from l-phenylalanine in 17% overall yield through 13 steps via condensation…”
Get full text

Live-cell imaging of nuclear–chromosomal dynamics in bovine in vitro fertilised embryos by Yao, Tatsuma, Suzuki, Rie, Furuta, Natsuki, Suzuki, Yuka, Kabe, Kyoko, Tokoro, Mikiko, Sugawara, Atsushi, Yajima, Akira, Nagasawa, Tomohiro, Matoba, Satoko, Yamagata, Kazuo, Sugimura, Satoshi

“…Nuclear/chromosomal integrity is an important prerequisite for the assessment of embryo quality in artificial reproductive technology. However, lipid-rich dark…”
Get full text

Synthesis of aspergillide A from a synthetic intermediate of aspergillide B by Nagasawa, Tomohiro, Kuwahara, Shigefumi

“…The first synthesis of aspergillide A, a cytotoxin produced by a marine-derived fungus, has been achieved from a synthetic intermediate of aspergillide B by…”
Get full text

Stereoselective Approach to the Racemic Oxatetracyclic Core of Platensimycin by Horii, Sakuya, Torihata, Munefumi, Nagasawa, Tomohiro, Kuwahara, Shigefumi

“…A highly stereoselective synthesis of the racemic oxatetracyclic core of platensimycin has been accomplished from a known bicyclic epoxy lactone by an 11-step…”
Get full text

Enantioselective Total Synthesis of the Potent Anti-HIV Nucleoside EFdA by Kageyama, Masayuki, Nagasawa, Tomohiro, Yoshida, Mayumi, Ohrui, Hiroshi, Kuwahara, Shigefumi

“…A concise enantioselective total synthesis of 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA), an extremely potent anti-HIV agent, has been accomplished from…”
Get full text

Synthesis of aspergillide A via proline-catalyzed trans-to- cis isomerization of a substituted tetrahydropyran by Nagasawa, Tomohiro, Nukada, Tomoo, Kuwahara, Shigefumi

“…The transformation of a common synthetic intermediate of aspergillides B and C into aspergillide A, a cytotoxin produced by a marine-derived fungus, has been…”
Get full text

Total Synthesis of Aspergillides A, B, and C by Kuwahara, Shigefumi, Nagasawa, Tomohiro

Get full text

Enantioselective synthesis of rumphellaone A via epoxy nitrile cyclization by Hirokawa, Takafumi, Nagasawa, Tomohiro, Kuwahara, Shigefumi

“…The first enantioselective synthesis of rumphellaone A, a cytotoxic 4,5- seco-caryophyllane derivative incorporating a γ-lactone ring as its structural…”
Get full text

Enantioselective synthesis of aspergillide B by Nagasawa, T.(Tohoku Univ., Sendai (Japan)), Kuwahara, S

“…The enantioselective synthesis of aspergillide B, a 14-membered macrocyclic cytotoxin, was achieved in a 49% yield via 7 steps from a synthetic intermediate of…”
Get full text

Concise Synthesis of the Anti-HIV Nucleoside EFdA by KAGEYAMA, Masayuki, MIYAGI, Takuho, YOSHIDA, Mayumi, NAGASAWA, Tomohiro, OHRUI, Hiroshi, KUWAHARA, Shigefumi

“…EFdA (4'-ethynyl-2-fluoro-2'-deoxyadenosine), a nucleoside reverse transcriptase inhibitor with extremely potent anti-HIV activity, was concisely synthesized…”
Get full text

Formal Total Synthesis of Lactimidomycin by Nagasawa, Tomohiro, Kuwahara, Shigefumi

“…A concise synthesis of an intermediate of lactimidomycin, a glutarimide-containing macrocyclic polyketide produced by an actinomycete, has been accomplished in…”
Get full text

Enantioselective Total Synthesis of Aspergillide C by Nagasawa, Tomohiro, Kuwahara, Shigefumi

“…The first enantioselective total synthesis of aspergillide C, a cytotoxic 14-membered macrolide isolated from the marine-derived fungus Aspergillus ostianus,…”
Get full text

Synthesis of (±)-lecanindole D by Asanuma, Akiko, Enomoto, Masaru, Nagasawa, Tomohiro, Kuwahara, Shigefumi

“…The first synthesis of the racemate of lecanindole D, an indole sesquiterpenoid with potent and selective agonist activity toward the progesterone receptor,…”
Get full text

Enantioselective total synthesis of idesolide via NaHCO3-promoted dimerization by Nagasawa, Tomohiro, Shimada, Naoyuki, Torihata, Munefumi, Kuwahara, Shigefumi

Get full text

Enantioselective total synthesis of idesolide via NaHCO 3-promoted dimerization by Nagasawa, Tomohiro, Shimada, Naoyuki, Torihata, Munefumi, Kuwahara, Shigefumi

“…The enantioselective total synthesis of idesolide has been accomplished in 20% overall yield from a known allylic alcohol by a nine-step sequence involving the…”
Get full text