Search Results - "Nagasaka, Kota"

Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins by Wutz, Gordana, Várnai, Csilla, Nagasaka, Kota, Cisneros, David A, Stocsits, Roman R, Tang, Wen, Schoenfelder, Stefan, Jessberger, Gregor, Muhar, Matthias, Hossain, M Julius, Walther, Nike, Koch, Birgit, Kueblbeck, Moritz, Ellenberg, Jan, Zuber, Johannes, Fraser, Peter, Peters, Jan‐Michael

“…Mammalian genomes are spatially organized into compartments, topologically associating domains (TADs), and loops to facilitate gene regulation and other…”
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ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesinSTAG1 from WAPL by Wutz, Gordana, Ladurner, Rene, St Hilaire, Brian Glenn, Stocsits, Roman R, Nagasaka, Kota, Pignard, Benoit, Sanborn, Adrian, Tang, Wen, Várnai, Csilla, Ivanov, Miroslav P, Schoenfelder, Stefan, van der Lelij, Petra, Huang, Xingfan, Dürnberger, Gerhard, Roitinger, Elisabeth, Mechtler, Karl, Davidson, Iain Finley, Fraser, Peter, Lieberman-Aiden, Erez, Peters, Jan-Michael

“…Eukaryotic genomes are folded into loops. It is thought that these are formed by cohesin complexes via extrusion, either until loop expansion is arrested by…”
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Werner syndrome helicase is a selective vulnerability of microsatellite instability-high tumor cells by Lieb, Simone, Blaha-Ostermann, Silvia, Kamper, Elisabeth, Rippka, Janine, Schwarz, Cornelia, Ehrenhöfer-Wölfer, Katharina, Schlattl, Andreas, Wernitznig, Andreas, Lipp, Jesse J, Nagasaka, Kota, van der Lelij, Petra, Bader, Gerd, Koi, Minoru, Goel, Ajay, Neumüller, Ralph A, Peters, Jan-Michael, Kraut, Norbert, Pearson, Mark A, Petronczki, Mark, Wöhrle, Simon

“…Targeted cancer therapy is based on exploiting selective dependencies of tumor cells. By leveraging recent functional screening data of cancer cell lines we…”
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Absolute quantification of cohesin, CTCF and their regulators in human cells by Holzmann, Johann, Politi, Antonio Z, Nagasaka, Kota, Hantsche-Grininger, Merle, Walther, Nike, Koch, Birgit, Fuchs, Johannes, Dürnberger, Gerhard, Tang, Wen, Ladurner, Rene, Stocsits, Roman R, Busslinger, Georg A, Novák, Béla, Mechtler, Karl, Davidson, Iain Finley, Ellenberg, Jan, Peters, Jan-Michael

“…The organisation of mammalian genomes into loops and topologically associating domains (TADs) contributes to chromatin structure, gene expression and…”
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Sister chromatid resolution is an intrinsic part of chromosome organization in prophase by Nagasaka, Kota, Hossain, M. Julius, Roberti, M. Julia, Ellenberg, Jan, Hirota, Toru

“…The imaging of individually labelled sister chromatids allows Nagasaka  et al.  to conclude that mitotic sister chromatin resolution begins in prophase and…”
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Kinetochore stretching-mediated rapid silencing of the spindle-assembly checkpoint required for failsafe chromosome segregation by Uchida, Kazuhiko S.K., Jo, Minji, Nagasaka, Kota, Takahashi, Motoko, Shindo, Norihisa, Shibata, Katsushi, Tanaka, Kozo, Masumoto, Hiroshi, Fukagawa, Tatsuo, Hirota, Toru

“…The spindle-assembly checkpoint facilitates mitotic fidelity by delaying anaphase onset in response to microtubule vacancy at kinetochores. Following…”
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The initial phase of chromosome condensation requires Cdk1-mediated phosphorylation of the CAP-D3 subunit of condensin II by Abe, Satoshi, Nagasaka, Kota, Hirayama, Youko, Kozuka-Hata, Hiroko, Oyama, Masaaki, Aoyagi, Yutaka, Obuse, Chikashi, Hirota, Toru

“…The cell cycle transition from interphase into mitosis is best characterized by the appearance of condensed chromosomes that become microscopically visible as…”
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Clarifying the role of condensin in shaping chromosomes by Nagasaka, Kota, Hirota, Toru

“…A major controversy in the field of chromosome research has been whether condensin is required for achieving the highly compacted state of chromatin fibres in…”
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CTCF is a DNA-tension-dependent barrier to cohesin-mediated loop extrusion by Davidson, Iain F., Barth, Roman, Zaczek, Maciej, van der Torre, Jaco, Tang, Wen, Nagasaka, Kota, Janissen, Richard, Kerssemakers, Jacob, Wutz, Gordana, Dekker, Cees, Peters, Jan-Michael

“…In eukaryotes, genomic DNA is extruded into loops by cohesin 1 . By restraining this process, the DNA-binding protein CCCTC-binding factor (CTCF) generates…”
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Wapl repression by Pax5 promotes V gene recombination by Igh loop extrusion by Hill, Louisa, Ebert, Anja, Jaritz, Markus, Wutz, Gordana, Nagasaka, Kota, Tagoh, Hiromi, Kostanova-Poliakova, Daniela, Schindler, Karina, Sun, Qiong, Bönelt, Peter, Fischer, Maria, Peters, Jan-Michael, Busslinger, Meinrad

“…Nuclear processes, such as V(D)J recombination, are orchestrated by the three-dimensional organization of chromosomes at multiple levels, including…”
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Cohesin mediates DNA loop extrusion and sister chromatid cohesion by distinct mechanisms by Nagasaka, Kota, Davidson, Iain F, Stocsits, Roman R, Tang, Wen, Wutz, Gordana, Batty, Paul, Panarotto, Melanie, Litos, Gabriele, Schleiffer, Alexander, Gerlich, Daniel W, Peters, Jan-Michael

“…Cohesin connects CTCF-binding sites and other genomic loci in cis to form chromatin loops and replicated DNA molecules in trans to mediate sister chromatid…”
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Abstract 2560: Werner syndrome helicase is a selective vulnerability of microsatellite instability-high tumor cells by Lieb, Simone, Blaha-Ostermann, Silvia, Kamper, Elisabeth, Ehrenhöfer-Wölfer, Katharina, Schlattl, Andreas, Wernitznig, Andreas, Lipp, Jesse, Nagasaka, Kota, Bader, Gerd, Neumueller, Ralph, Kraut, Norbert, Pearson, Mark, Woehrle, Simon, Petronczki, Mark

“…Abstract Targeted cancer therapy is based on exploiting selective dependencies of tumor cells. By leveraging recent large-scale genomic profiling and…”
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Author Correction: Sister chromatid resolution is an intrinsic part of chromosome organization in prophase by Nagasaka, Kota, Hossain, M. Julius, Roberti, M. Julia, Ellenberg, Jan, Hirota, Toru

“…In the version of this Letter originally published, the authors omitted a citation of an early study demonstrating topoisomerase-II-dependent sister chromatid…”
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ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesin.sup.STAG1 from WAPL by Wutz, Gordana, Ladurner, Rene, St Hilaire, Brian Glenn, Stocsits, Roman R, Nagasaka, Kota, Pignard, Benoit, Sanborn, Adrian, Tang, Wen, Várnai, Csilla, Ivanov, Miroslav P, Schoenfelder, Stefan, van der Lelij, Petra, Huang, Xingfan, Dürnberger, Gerhard, Roitinger, Elisabeth, Mechtler, Karl, Davidson, Iain Finley, Fraser, Peter, Lieberman-Aiden, Erez, Peters, Jan-Michael

“…Eukaryotic genomes are folded into loops. It is thought that these are formed by cohesin complexes via extrusion, either until loop expansion is arrested by…”
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ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesin STAG1 from WAPL by Wutz, Gordana, Ladurner, Rene, St Hilaire, Brian Glenn, Stocsits, Roman R, Nagasaka, Kota, Pignard, Benoit, Sanborn, Adrian, Tang, Wen, Várnai, Csilla, Ivanov, Miroslav P, Schoenfelder, Stefan, van der Lelij, Petra, Huang, Xingfan, Dürnberger, Gerhard, Roitinger, Elisabeth, Mechtler, Karl, Davidson, Iain Finley, Fraser, Peter, Lieberman-Aiden, Erez, Peters, Jan-Michael

“…Eukaryotic genomes are folded into loops. It is thought that these are formed by cohesin complexes extrusion, either until loop expansion is arrested by CTCF…”
Get full text