Search Results - "Nagao, Itsuma"

High-fat diet enhances cell proliferation and compromises intestinal permeability in a translational canine intestinal organoid model by Nagao, Itsuma, Ambrosini, Yoko M

“…Emerging evidence underscores the responsiveness of the mammalian intestine to dietary cues, notably through the involvement of LGR5 + intestinal stem cells in…”
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Comprehensive gene expression analysis in gallbladder mucosal epithelial cells of dogs with gallbladder mucocele by Nagao, Itsuma, Motegi, Tomoki, Goto‐Koshino, Yuko, Tsuboi, Masaya, Takahashi, Naohiro, Chambers, James K., Uchida, Kazuyuki, Baba, Kenji, Tomiyasu, Hirotaka, Okuda, Masaru

“…Background Gallbladder mucocele (GBM) is a common disease in the canine gallbladder. Although the pathogenesis of GBM remains unclear, we recently reported…”
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Ion channel function in translational bovine gallbladder cholangiocyte organoids: establishment and characterization of a novel model system by Nagao, Itsuma, Ambrosini, Yoko M

“…The study of biliary physiology and pathophysiology has long been hindered by the lack of models that accurately reflect the complex functions of the biliary…”
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Polyoxazoline-conjugated porcine serum albumin as an artificial plasma expander for dogs by Okamoto, Wataru, Usui, Tomone, Hasegawa, Mai, Kobayashi, Tatsuhiro, Fujisawa, Junya, Taguchi, Kazuaki, Matsumoto, Kazuaki, Kohno, Mitsutomo, Iwazaki, Masayuki, Shimano, Shotaro, Nagao, Itsuma, Toyoda, Hiroto, Matsumura, Naoki, Tomiyasu, Hirotaka, Tochinai, Ryota, Komatsu, Teruyuki

“…Veterinary medicine has made tremendous progress for domestic dogs, which are irreplaceable family members enriching human life. Nevertheless, no adequate…”
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Effects of proportions of carbohydrates and fats in diets on mucin concentration and bile composition in gallbladder of dogs by SHIKANO, Riho, OHNO, Koichi, NAGAHARA, Takuro, NAGAO, Itsuma, TOYODA, Hiroto, NAKAGAWA, Taisuke, GOTO-KOSHINO, Yuko, CHAMBERS, James K, TOMIYASU, Hirotaka, TSUJIMOTO, Hajime

“…The associations of diet compositions with mucin secretion in gallbladder have not been investigated in dogs. This study aimed to examine the effects of a…”
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Evaluation of the degree and distribution of lymphangiectasia in full-thickness canine small intestinal specimens diagnosed with lymphoplasmacytic enteritis and granulomatous lymphangitis by NAGAHARA, Takuro, OHNO, Koichi, NAGAO, Itsuma, NAKAGAWA, Taisuke, GOTO-KOSHINO, Yuko, TSUBOI, Masaya, CHAMBERS, James K., UCHIDA, Kazuyuki, TOMIYASU, Hirotaka, TSUJIMOTO, Hajime

“…Intestinal lymphangiectasia (IL) is often observed in dogs with chronic small intestinal diseases. Hypoplasia of the lymphatic vessel due to decreased…”
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Association between intestinal lymphangiectasia and expression of inducible nitric oxide synthase in dogs with lymphoplasmacytic enteritis by NAGAHARA, Takuro, OHNO, Koichi, NAGAO, Itsuma, NAKAGAWA, Taisuke, GOTO-KOSHINO, Yuko, TSUBOI, Masaya, CHAMBERS, James K., UCHIDA, Kazuyuki, TOMIYASU, Hirotaka, TSUJIMOTO, Hajime

“…Intestinal lymphangiectasia (IL) is a common complication in dogs. Since nitric oxide (NO) is known to relax the lymphatic vessel, we evaluated inducible NO…”
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Farm and Companion Animal Organoid Models in Translational Research: A Powerful Tool to Bridge the Gap Between Mice and Humans by Kawasaki, Minae, Goyama, Takashi, Tachibana, Yurika, Nagao, Itsuma, Ambrosini, Yoko M

“…Animal organoid models derived from farm and companion animals have great potential to contribute to human health as a One Health initiative, which recognize a…”
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Investigation of the mutations in the genes involved in Janus kinase/signal transducer and activator of transcription pathway in canine large cell gastrointestinal lymphoma by TSURUTA, Takumi, MATSUMURA, Naoki, MIZUKAMI, Keijiro, GOTO-KOSHINO, Yuko, AOI, Tomomi, YAMADA, Ryoko, NAGAO, Itsuma, SAKAMOTO, Megumi, NAKAGAWA, Taisuke, FUKUOKA, Ray, OHMI, Aki, CHAMBERS, James K, UCHIDA, Kazuyuki, MOMOZAWA, Yukihide, TOMIYASU, Hirotaka

“…Canine gastrointestinal lymphoma is known to be of T-cell origin in most cases, but the molecular biological aberrations have not been clarified. In human…”
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Enterohemorrhagic Escherichia coli (EHEC) disrupts intestinal barrier integrity in translational canine stem cell-derived monolayers by Nagao, Itsuma, Kawasaki, Minae, Goyama, Takashi, Kim, Hyun Jung, Call, Douglas R, Ambrosini, Yoko M

“…This study addresses the gap in translatable models for investigating Enterohemorrhagic (EHEC) infections, particularly relevant to both canine and human…”
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Changes in the coagulation parameters in dogs with protein-losing enteropathy between before and after treatment by NAGAHARA, Takuro, OHNO, Koichi, NAGAO, Itsuma, NAKAGAWA, Taisuke, YOKOYAMA, Nozomu, OHMI, Aki, GOTO-KOSHINO, Yuko, CHAMBERS, James K., UCHIDA, Kazuyuki, TOMIYASU, Hirotaka, TSUJIMOTO, Hajime

“…Protein-losing enteropathy (PLE) is known to induce hypercoagulability and resultant thromboembolism in dogs. We hypothesized that hypercoagulability would…”
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Evaluation of visceral fat mass in dogs by computed tomography by NAGAO, Itsuma, OHNO, Koichi, NAGAHARA, Takuro, YOKOYAMA, Nozomu, NAKAGAWA, Taisuke, FUJIWARA, Reina, YAMAMOTO, Kie, GOTO-KOSHINO, Yuko, TOMIYASU, Hirotaka, TSUJIMOTO, Hajime

“…In human medicine, computed tomography (CT) is the gold standard for visceral fat measurement. Research shows that the visceral fat area (VFA) of the umbilical…”
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MUC5AC and MUC5B expression in canine gallbladder mucocele epithelial cells by NAGAO, Itsuma, TSUJI, Kanako, GOTO-KOSHINO, Yuko, TSUBOI, Masaya, CHAMBERS, James K., UCHIDA, Kazuyuki, KAMBAYASHI, Satoshi, TOMIYASU, Hirotaka, BABA, Kenji, OKUDA, Masaru

“…Gallbladder mucocele (GBM) is one of the most common gallbladder diseases in dogs. Its pathogenesis has not yet been clarified, but excessive accumulation of a…”
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Case Report: Tricuspid Annuloplasty for Right-Sided Congestive Heart Failure Secondary to Pulmonary Hypertension in a Dog by Mizuno, Takeshi, Sasaki, Kenta, Suzuki, Sayaka, Nagao, Itsuma, Isayama, Noriko

“…An 11-year-old, 12.3-kg, female Miniature Dachshund was presented to our institution with ascites of unknown etiology. The dog had been administered moxidectin…”
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Sa1917 A TRANSLATIONAL CANINE INTESTINAL ORGANOID MODEL TO CHARACTERIZE THE IMPACT OF HIGH-FAT DIET by Nagao, Itsuma, Ambrosini, Yoko M.

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Sa1220 3D MORPHOGENESIS AND BACTERIAL CO-CULTURE IN A CANINE GUTON-A-CHIP USING BIOPSY-DERIVED INTESTINAL ORGANOIDS FROM HEALTHY AND IBD PATIENTS by Nagao, Itsuma, Nakazawa, Meg, Ambrosini, Yoko M.

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3D MORPHOGENESIS AND BACTERIAL CO-CULTURE IN A CANINE GUT-ON-A-CHIP USING BIOPSY-DERIVED INTESTINAL ORGANOIDS FROM HEALTHY AND IBD PATIENTS by Nagao, Itsuma, Nakazawa, Meg, Ambrosini, Yoko

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3D MORPHOGENESIS AND BACTERIAL CO-CULTURE IN A CANINE GUT-ON-A-CHIP USING BIOPSY-DERIVED INTESTINAL ORGANOIDS FROM HEALTHY AND IBD PATIENTS by Nagao, Itsuma, Nakazawa, Meg, Ambrosini, Yoko

“…The understanding of the role of intestinal bacteria in various intestinal diseases has been limited due to the lack of suitable in vitro models. However,…”
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Proinflammatory cytokines suppress stemness-related properties and expression of tight junction in canine intestinal organoids by Nakazawa, Meg, Nagao, Itsuma, Ambrosini, Yoko M.

“…Recent advancements in canine intestinal organoid research have paved the way for the development of enhanced in vitro models, crucial for exploring intestinal…”
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Three-Dimensional Morphogenesis in Canine Gut-on-a-Chip Using Intestinal Organoids Derived from Inflammatory Bowel Disease Patients by Nagao, Itsuma, Nakazawa, Meg, Ambrosini, Yoko M

“…Canine intestines possess similarities in anatomy, microbiology, and physiology to those of humans, and dogs naturally develop spontaneous intestinal disorders…”
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