Search Results - "Naganuma, Rio"

The polypeptide antibiotic polymyxin B acts as a pro-inflammatory irritant by preferentially targeting macrophages by Kagi, Tomohiro, Naganuma, Rio, Inoue, Aya, Noguchi, Takuya, Hamano, Shuhei, Sekiguchi, Yuto, Hwang, Gi-Wook, Hirata, Yusuke, Matsuzawa, Atsushi

“…Polymyxin B (PMB) is an essential antibiotic active against multidrug-resistant bacteria, such as multidrug-resistant Pseudomonas aeruginosa (MDRP). However,…”
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Gefitinib initiates sterile inflammation by promoting IL-1β and HMGB1 release via two distinct mechanisms by Noguchi, Takuya, Sekiguchi, Yuto, Kudoh, Yuki, Naganuma, Rio, Kagi, Tomohiro, Nishidate, Akiko, Maeda, Kazuhiro, Ishii, Chizuru, Toyama, Takashi, Hirata, Yusuke, Hwang, Gi-Wook, Matsuzawa, Atsushi

“…Anticancer drug gefitinib causes inflammation-based side effects, such as interstitial pneumonitis. However, its mechanisms remain unknown. Here, we provide…”
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The NLRP3 Inflammasome Is a Major Cause of Acute Renal Failure Induced by Polypeptide Antibiotics by Kagi, Tomohiro, Inoue, Aya, Noguchi, Takuya, Suzuki, Wakana, Takano, Saya, Otani, Kohei, Naganuma, Rio, Sekiguchi, Yuto, Hirata, Yusuke, Shindo, Sawako, Hwang, Gi-Wook, Matsuzawa, Atsushi

“…Drug-induced acute renal failure (ARF) is a public health concern that hinders optimal drug therapy. However, pathological mechanisms of drug-induced ARF…”
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