Search Results - "Nagano, Luis Fernando"

HUWE1 cooperates with RAS activation to control leukemia cell proliferation and human hematopoietic stem cells differentiation fate by Ruckert, Mariana Tannús, Brouwers-Vos, Annet Z., Nagano, Luis Fernando P., Schuringa, Jan Jacob, Silveira, Vanessa Silva

“…Acute myeloid leukemia (AML) is a poor prognosis hematopoietic malignance characterized by abnormal proliferation and differentiation of hematopoietic stem…”
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SHOC2 scaffold protein modulates daunorubicin-induced cell death through p53 modulation in lymphoid leukemia cells by Silveira, Vanessa Silva, Borges, Kleiton Silva, Santos, Verena Silva, Ruckert, Mariana Tannús, Vieira, Gabriela Maciel, Vasconcelos, Elton José Rosas, Nagano, Luis Fernando Peinado, Tone, Luiz Gonzaga, Scrideli, Carlos Alberto

“…SHOC2 scaffold protein has been mainly related to oncogenic ERK signaling through the RAS-SHOC2-PP1 phosphatase complex. In leukemic cells however, SHOC2…”
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A coordinated approach for the assessment of molecular subgroups in pediatric ependymomas using low-cost methods by de Sousa, Graziella Ribeiro, Lira, Régia Caroline Peixoto, de Almeida Magalhães, Taciani, da Silva, Keteryne Rodrigues, Nagano, Luis Fernando Peinado, Saggioro, Fabiano Pinto, Baroni, Mirella, Marie, Suely Kazue Nagahashi, Oba-Shinjo, Sueli Mieko, Brandelise, Silvia, de Paula Queiroz, Rosane Gomes, Brassesco, María Sol, Scrideli, Carlos Alberto, Tone, Luiz Gonzaga, Valera, Elvis Terci

“…Although ependymoma (EPN) molecular subgroups have been well established by integrated high-throughput platforms, low- and middle-income countries still need…”
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Identification of ITPR1 as a Hub Gene of Group 3 Medulloblastoma and Coregulated Genes with Potential Prognostic Values by das Chagas, Pablo Ferreira, de Sousa, Graziella Ribeiro, Veronez, Luciana Chain, Martins-da-Silva, Andrea, Corrêa, Carolina Alves Pereira, Cruzeiro, Gustavo Alencastro Veiga, Nagano, Luis Fernando Peinado, Queiroz, Rosane Gomes de Paula, Marie, Suely Kazue Nagahashi, Brandalise, Silvia Regina, Scrideli, Carlos Alberto, Tone, Luiz Gonzaga, Valera, Elvis Terci

“…The Group 3 Medulloblastoma (Grp3-MB) is an aggressive molecular subtype with a high incidence of metastasis and deaths. In this study, were used an RNA…”
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Activation of Hedgehog signaling by the oncogenic RELA fusion reveals a primary cilia-dependent vulnerability in supratentorial ependymoma by de Almeida Magalhães, Taciani, Alencastro Veiga Cruzeiro, Gustavo, Ribeiro de Sousa, Graziella, Englinger, Bernhard, Fernando Peinado Nagano, Luis, Ancliffe, Mathew, Rodrigues da Silva, Keteryne, Jiang, Li, Gojo, Johannes, Cherry Liu, Yulu, Carline, Brooke, Kuchibhotla, Mani, Pinto Saggioro, Fabiano, Kazue Nagahashi Marie, Suely, Mieko Oba-Shinjo, Sueli, Andres Yunes, José, Gomes de Paula Queiroz, Rosane, Alberto Scrideli, Carlos, Endersby, Raelene, Filbin, Mariella G, Silva Borges, Kleiton, Salic, Adrian, Gonzaga Tone, Luiz, Valera, Elvis Terci

“…Supratentorial RELA fusion (ST-RELA) ependymomas (EPNs) are resistant tumors without an approved chemotherapeutic treatment. Unfortunately, the molecular…”
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Low PRKAB2 Expression Is Associated with Poor Outcomes in Pediatric Adrenocortical Tumors, and Treatment with Rottlerin Increases the PRKAB2 Level and Inhibits Tumorigenic Aspects in the NCI-H295R Adrenocortical Cancer Cell Line by Xavier, Alcides Euzebio Tavares, Veronez, Luciana Chain, Nagano, Luís Fernando Peinado, Correa, Carolina Alves Pereira, Baroni, Mirela, Ramos, Milena Silva, Queiroz, Rosane de Gomes de Paula, Fernandes Molina, Carlos Augusto, Yunes, José Andres, Brandalise, Silvia Regina, Antonini, Sonir Antonio Rauber, Tone, Luiz Gonzaga, Valera, Elvis Terci, Scrideli, Carlos Alberto

“…Pediatric adrenocortical tumors (ACTs) are rare, highly heterogeneous neoplasms with limited therapeutic options, making the investigation of new targets with…”
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Atypical phosphatase DUSP11 inhibition promotes nc886 expression and potentiates gemcitabine-mediated cell death through NF-kB modulation by Santos, Verena Silva, Vieira, Gabriela Maciel, Ruckert, Mariana Tannús, Andrade, Pamela Viani de, Nagano, Luis Fernando, Brunaldi, Mariângela Ottoboni, Dos Santos, José Sebastião, Silveira, Vanessa Silva

“…Pancreatic ductal adenocarcinoma (PDAC) represents one of the deadliest cancers among all solid tumors. First-line treatment relies on gemcitabine (Gem) and…”
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Low IPRKAB2/I Expression Is Associated with Poor Outcomes in Pediatric Adrenocortical Tumors, and Treatment with Rottlerin Increases the IPRKAB2/I Level and Inhibits Tumorigenic Aspects in the NCI-H295R Adrenocortical Cancer Cell Line by Xavier, Alcides Euzebio Tavares, Veronez, Luciana Chain, Nagano, Luís Fernando Peinado, Correa, Carolina Alves Pereira, Baroni, Mirela, Ramos, Milena Silva, Queiroz, Rosane de Gomes de Paula, Fernandes Molina, Carlos Augusto, Yunes, José Andres, Brandalise, Silvia Regina, Antonini, Sonir Antonio Rauber, Tone, Luiz Gonzaga, Valera, Elvis Terci, Scrideli, Carlos Alberto

“…Adrenocortical tumors are rare neoplasms with an uncertain prognosis. A greater understanding of the biology of these tumors will allow new therapeutic targets…”
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