A postmenopausal osteoporotic woman losing bone mineral density despite bisphosphonates

Bisphosphonates are pyrophosphate analogues, with a strong affinity for bones. They inhibit bone resorption and are currently the first choice of treatment for osteoporosis. Bisphosphonates should be taken in a specific manner and for at least one year to be effective in the maintenance and improvem...

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Bibliographic Details
Published in:	Malaysian family physician Vol. 8; no. 2; pp. 47 - 52
Main Authors:	Lai, P S M, Nagammai, T, Vethakkan, S R
Format:	Journal Article
Language:	English
Published:	Kuala Lumpur Academy of Family Physicians of Malaysia 2013 Academy of Family Physician of Malaysia
Subjects:	bisphosphonate bone mineral density Case Report osteoporosis postmenopausal
Online Access:	Get full text
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Summary:	Bisphosphonates are pyrophosphate analogues, with a strong affinity for bones. They inhibit bone resorption and are currently the first choice of treatment for osteoporosis. Bisphosphonates should be taken in a specific manner and for at least one year to be effective in the maintenance and improvement of bone mineral density (BMD), as well as for protection against fractures. We report a case of a postmenospausal osteoporotic woman who lost BMD despite being on bisphosphonate therapy for eight years, highlighting issues that a primary care doctor needs to address before deciding on the next best option.
ISSN:	1985-2274 1985-207X 1985-2274