Search Results - "Nagamatsu, Akemi"
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Predicting brain age from functional connectivity in symptomatic and preclinical Alzheimer disease
Published in NeuroImage (Orlando, Fla.) (01-08-2022)“…•A machine learning model can predict age from functional connectivity in controls.•Model estimates of age are significantly elevated in symptomatic Alzheimer…”
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Fishes of the upper rio Paraná basin: diversity, biogeography and conservation
Published in Neotropical Ichthyology (01-01-2024)“…Abstract The upper rio Paraná basin drains the most developed and environmentally degraded region in South America: the Brazilian southeast. While it is one of…”
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Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid
Published in Nature (London) (17-11-2022)Get full text
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Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid
Published in Nature (London) (17-11-2022)“…Macrophages are important players in the maintenance of tissue homeostasis 1 . Perivascular and leptomeningeal macrophages reside near the central nervous…”
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Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: a longitudinal observational study
Published in Lancet neurology (01-04-2022)“…Therapeutic modulation of TREM2-dependent microglial function might provide an additional strategy to slow the progression of Alzheimer's disease. Although…”
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Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study
Published in Lancet neurology (01-01-2023)“…Important insights into the early pathogenesis of Alzheimer's disease can be provided by studies of autosomal dominant Alzheimer's disease and Down syndrome…”
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Association of BDNF Val66Met With Tau Hyperphosphorylation and Cognition in Dominantly Inherited Alzheimer Disease
Published in JAMA neurology (01-03-2022)“…Allelic variation in the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism moderates increases in cerebrospinal fluid (CSF) levels of tau and…”
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Generation of a gene-corrected human isogenic iPSC line from an Alzheimer’s disease iPSC line carrying the PSEN1 H163R mutation
Published in Stem cell research (01-09-2024)“…We report the generation of a gene-edited human induced pluripotent stem cell (iPSC) line from an Alzheimer’s disease patient-derived iPSC line harbouring the…”
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