Search Results - "Nagai, Yurie"

Construction and evaluation of a self-replicative RNA vaccine against SARS-CoV-2 using yellow fever virus replicon by Akina Nakamura, Tomohiro Kotaki, Yurie Nagai, Shunta Takazawa, Kenzo Tokunaga, Masanori Kameoka

“…The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is a global threat. To…”
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Construction and evaluation of a self-replicative RNA vaccine against SARS-CoV-2 using yellow fever virus replicon by Nakamura, Akina, Kotaki, Tomohiro, Nagai, Yurie, Takazawa, Shunta, Tokunaga, Kenzo, Kameoka, Masanori

“…The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is a global threat. To…”
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Efficacy of the novel tubulin polymerization inhibitor PTC‐028 for myelodysplastic syndrome by Zhong, Cheng, Kayamori, Kensuke, Koide, Shuhei, Shinoda, Daisuke, Oshima, Motohiko, Nakajima‐Takagi, Yaeko, Nagai, Yurie, Mimura, Naoya, Sakaida, Emiko, Yamazaki, Satoshi, Iwano, Satoshi, Miyawaki, Atsushi, Ito, Ryoji, Tohyama, Kaoru, Yamaguchi, Kiyoshi, Furukawa, Yoichi, Lennox, William, Sheedy, Josephine, Weetall, Marla, Iwama, Atsushi

“…Monomer tubulin polymerize into microtubules, which are highly dynamic and play a critical role in mitosis. Therefore, microtubule dynamics are an important…”
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The combination of the tubulin binding small molecule PTC596 and proteasome inhibitors suppresses the growth of myeloma cells by Nagai, Yurie, Mimura, Naoya, Rizq, Ola, Isshiki, Yusuke, Oshima, Motohiko, Rizk, Mohamed, Saraya, Atsunori, Koide, Shuhei, Nakajima-Takagi, Yaeko, Miyota, Makiko, Chiba, Tetsuhiro, Oshima-Hasegawa, Nagisa, Muto, Tomoya, Tsukamoto, Shokichi, Mitsukawa, Shio, Takeda, Yusuke, Ohwada, Chikako, Takeuchi, Masahiro, Iseki, Tohru, Nakaseko, Chiaki, Lennox, William, Sheedy, Josephine, Weetall, Marla, Yokote, Koutaro, Iwama, Atsushi, Sakaida, Emiko

“…The novel small molecule PTC596 inhibits microtubule polymerization and its clinical development has been initiated for some solid cancers. We herein…”
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Genetic subtype classification using a simplified algorithm and mutational characteristics of diffuse large B‐cell lymphoma in a Japanese cohort by Mishina, Tatsuzo, Oshima‐Hasegawa, Nagisa, Tsukamoto, Shokichi, Fukuyo, Masaki, Kageyama, Hajime, Muto, Tomoya, Mimura, Naoya, Rahmutulla, Bahityar, Nagai, Yurie, Kayamori, Kensuke, Hino, Yutaro, Mitsukawa, Shio, Takeda, Yusuke, Ohwada, Chikako, Takeuchi, Masahiro, Tsujimura, Hideki, Iseki, Tohru, Nakaseko, Chiaki, Ikeda, Jun-ichiro, Itami, Makiko, Yokote, Koutaro, Ohara, Osamu, Kaneda, Atsushi, Sakaida, Emiko

“…Summary Recent large‐scale genetic studies have proposed a new genetic classification of diffuse large B‐cell lymphoma (DLBCL), which is clinically and…”
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Successful second autologous stem-cell transplantation for patients with relapsed and refractory POEMS syndrome by Shibamiya, Asuka, Ohwada, Chikako, Ishii, Arata, Mishina, Tatsuzo, Nagai, Yurie, Hino, Yutaro, Kayamori, Kensuke, Oshima-Hasegawa, Nagisa, Muto, Tomoya, Tsukamoto, Shokichi, Takeda, Yusuke, Mitsukawa, Shio, Mimura, Naoya, Iseki, Tohru, Misawa, Sonoko, Kuwabara, Satoshi, Nakaseko, Chiaki, Sakaida, Emiko

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Acquired von Willebrand Syndrome due to Aortic Valve Stenosis in a Case with Antiphospholipid Antibody by Tanaka, Hiroaki, Nagai, Yurie, Kuwabara, Chihiro, Shimizu, Ryo, Umeki, Akihide, Yamamoto, Tetsufumi

“…Acquired von Willebrand syndrome (AVWS) is a bleeding disorder caused by an acquired deficiency of von Willebrand factor (vWF). Some patients with AVWS show a…”
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Japanese Encephalitis DNA Vaccines with Epitope Modification Reduce the Induction of Cross-Reactive Antibodies against Dengue Virus and Antibody-Dependent Enhancement of Dengue Virus Infection by Kotaki, Tomohiro, Nagai, Yurie, Yamanaka, Atsushi, Konishi, Eiji, Kameoka, Masanori

“…Infection with viruses belonging to the genus Flavivirus, such as Japanese encephalitis virus (JEV) and dengue virus (DENV), is a worldwide health problem…”
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Outcomes of poor peripheral blood stem cell mobilizers with multiple myeloma at the first mobilization: A multicenter retrospective study in Japan by Miyamoto‐Nagai, Yurie, Mimura, Naoya, Tsukada, Nobuhiro, Aotsuka, Nobuyuki, Ri, Masaki, Katsuoka, Yuna, Wakayama, Toshio, Suzuki, Rikio, Harazaki, Yoriko, Matsumoto, Morio, Kumagai, Kyoya, Miyake, Takaaki, Ozaki, Shuji, Shono, Katsuhiro, Tanaka, Hiroaki, Shimura, Arika, Kuroda, Yoshiaki, Sunami, Kazutaka, Suzuki, Kazuhito, Yamashita, Takeshi, Shimizu, Kazuyuki, Murakami, Hirokazu, Abe, Masahiro, Nakaseko, Chiaki, Sakaida, Emiko

“…Autologous stem cell transplantation (ASCT) remains an important therapeutic strategy for multiple myeloma; however, a proportion of patients fail to mobilize…”
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Detection of clonal plasma cells in POEMS syndrome using multiparameter flow cytometry by Ishii, Arata, Tsukamoto, Shokichi, Mimura, Naoya, Miyamoto-Nagai, Yurie, Isshiki, Yusuke, Matsui, Shinichiro, Nakao, Sanshiro, Shibamiya, Asuka, Hino, Yutaro, Kayamori, Kensuke, Oshima-Hasegawa, Nagisa, Muto, Tomoya, Takeda, Yusuke, Suichi, Tomoki, Misawa, Sonoko, Ohwada, Chikako, Yokote, Koutaro, Kuwabara, Satoshi, Nakaseko, Chiaki, Takamatsu, Hiroyuki, Sakaida, Emiko

“…POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal protein [M-protein], and skin changes) is a rare systemic disorder characterized by…”
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Successful allogeneic bone marrow transplantation after massive gastrointestinal bleeding in a patient with myelodysplastic syndrome associated with intestinal Behçet-like disease by Ishii, Arata, Tsukamoto, Shokichi, Mishina, Tatsuzo, Izumi, Shintaro, Nagai, Yurie, Yamazaki, Miki, Hino, Yutaro, Kayamori, Kensuke, Oshima-Hasegawa, Nagisa, Muto, Tomoya, Mitsukawa, Shio, Takeda, Yusuke, Mimura, Naoya, Ohwada, Chikako, Nakaseko, Chiaki, Ikeda, Jun-ichiro, Sakaida, Emiko

“…A 45-year-old woman was diagnosed with myelodysplastic syndrome (MDS) with trisomy 8 and Behçet-like disease (BLD) with multiple colorectal ulcers. Nonspecific…”
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Unraveling unique features of plasma cell clones in POEMS syndrome with single-cell analysis by Isshiki, Yusuke, Oshima, Motohiko, Mimura, Naoya, Kayamori, Kensuke, Miyamoto-Nagai, Yurie, Seki, Masahide, Nakajima-Takagi, Yaeko, Kanamori, Takashi, Iwamoto, Eisuke, Muto, Tomoya, Tsukamoto, Shokichi, Takeda, Yusuke, Ohwada, Chikako, Misawa, Sonoko, Ikeda, Jun-ichiro, Sanada, Masashi, Kuwabara, Satoshi, Suzuki, Yutaka, Sakaida, Emiko, Nakaseko, Chiaki, Iwama, Atsushi

“…POEMS syndrome is a rare monoclonal plasma cell disorder, with unique symptoms distinct from those of other plasma cell neoplasms, including high serum VEGF…”
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Efficacy of Tubulin Polymerization Inhibitor in Myelodysplastic Syndrome by Zhong, Cheng, Kayamori, Kensuke, Koide, Shuhei, Shinoda, Daisuke, Oshima, Motohiko, Nakajima-Takagi, Yaeko, Nagai, Yurie, Mimura, Naoya, Lennox, William, Sheedy, Josephine, Weetall, Marla, Iwama, Atsushi

“…Background: Myelodysplastic Syndrome (MDS) is a clonal bone marrow disorder characterized by ineffective and clonal hematopoiesis accompanied by morphological…”
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Correction: UTX inactivation in germinal center B cells promotes the development of multiple myeloma with extramedullary disease by Rizq, Ola, Mimura, Naoya, Oshima, Motohiko, Momose, Shuji, Takayama, Naoya, Itokawa, Naoki, Koide, Shuhei, Shibamiya, Asuka, Miyamoto-Nagai, Yurie, Rizk, Mohamed, Nakajima-Takagi, Yaeko, Aoyama, Kazumasa, Wang, Changshan, Saraya, Atsunori, Ito, Ryoji, Seimiya, Masanori, Watanabe, Mariko, Yamasaki, Satoshi, Shibata, Tatsuhiro, Yamaguchi, Kiyoshi, Furukawa, Yoichi, Chiba, Tetsuhiro, Sakaida, Emiko, Nakaseko, Chiaki, Tamaru, Jun-ichi, Tai, Yu-Tzu, Anderson, Kenneth C., Honda, Hiroaki, Iwama, Atsushi

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UTX inactivation in germinal center B cells promotes the development of multiple myeloma with extramedullary disease by Rizq, Ola, Mimura, Naoya, Oshima, Motohiko, Momose, Shuji, Takayama, Naoya, Itokawa, Naoki, Koide, Shuhei, Shibamiya, Asuka, Miyamoto-Nagai, Yurie, Rizk, Mohamed, Nakajima-Takagi, Yaeko, Aoyama, Kazumasa, Wang, Changshan, Saraya, Atsunori, Ito, Ryoji, Seimiya, Masanori, Watanabe, Mariko, Yamasaki, Satoshi, Shibata, Tatsuhiro, Yamaguchi, Kiyoshi, Furukawa, Yoichi, Chiba, Tetsuhiro, Sakaida, Emiko, Nakaseko, Chiaki, Tamaru, Jun-ichi, Tai, Yu-Tzu, Anderson, Kenneth C., Honda, Hiroaki, Iwama, Atsushi

“…UTX/KDM6A, a histone H3K27 demethylase and a key component of the COMPASS complex, is frequently lost or mutated in cancer; however, its tumor suppressor…”
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Exhausted T Cells Characterized By Upregulation of Specific Transcription Factors Are Increased in a Mouse Model of De Novo Mature B Cell Neoplasms by Shibamiya, Asuka, Mimura, Naoya, Miyamoto-Nagai, Yurie, Koide, Shuhei, Oshima, Motohiko, Rizq, Ola, Aoyama, Kazumasa, Nakajima-Takagi, Yaeko, Kayamori, Kensuke, Isshiki, Yusuke, Oshima-Hasegawa, Nagisa, Muto, Tomoya, Tsukamoto, Shokichi, Takeda, Yusuke, Koyama-Nasu, Ryo, Chiba, Tetsuhiro, Honda, Hiroaki, Yokote, Koutaro, Iwama, Atsushi, Sakaida, Emiko

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The pathogenetic significance of exhausted T cells in a mouse model of mature B cell neoplasms by Shibamiya, Asuka, Miyamoto-Nagai, Yurie, Koide, Shuhei, Oshima, Motohiko, Rizq, Ola, Aoyama, Kazumasa, Nakajima-Takagi, Yaeko, Kato, Rei, Kayamori, Kensuke, Isshiki, Yusuke, Oshima-Hasegawa, Nagisa, Muto, Tomoya, Tsukamoto, Shokichi, Takeda, Yusuke, Koyama-Nasu, Ryo, Chiba, Tetsuhiro, Honda, Hiroaki, Yokote, Koutaro, Iwama, Atsushi, Sakaida, Emiko, Mimura, Naoya

“…Dysfunctional anti-tumor immunity has been implicated in the pathogenesis of mature B cell neoplasms, such as multiple myeloma and B cell lymphoma; however,…”
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Detection of Clonal Plasma Cells in POEMS Syndrome Using Multiparameter Flow Cytometry by Ishii, Arata, Tsukamoto, Shokichi, Mimura, Naoya, Nagai, Yurie, Matsui, Shinichiro, Nakao, Sanshiro, Shibamiya, Asuka, Hino, Yutaro, Kayamori, Kensuke, Oshima-Hasegawa, Nagisa, Muto, Tomoya, Mitsukawa, Shio, Takeda, Yusuke, Suichi, Tomoki, Misawa, Sonoko, Ohwada, Chikako, Yokote, Koutaro, Kuwabara, Satoshi, Nakaseko, Chiaki, Takamatsu, Hiroyuki, Sakaida, Emiko

“…Introduction POEMS syndrome is a rare systemic disorder characterized by various symptoms, including polyneuropathy, organomegaly, endocrinopathy, monoclonal…”
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3093 – DHODH INHIBITION SYNERGIZES WITH DNA-DEMETHYLATING AGENTS IN THE TREATMENT OF MYELODYSPLASTIC SYNDROMES by Kayamori, Kensuke, Kaito, Satoshi, Nagai, Yurie, Koide, Shuhei, Shinoda, Daisuke, Ohshima, Motohiko, Nakajima-Takagi, Yaeko, Yamashita, Masayuki, Zhong, Cheng, Mimura, Naoya, Yamazaki, Satoshi, Miyawaki, Atsushi, Ito, Ryoji, Tohyama, Kaoru, Weetall, Marla, Sakaida, Emiko, Iwama, Atsushi

“…Myelodysplastic syndrome (MDS) is a clonal bone marrow disorder characterized by ineffective and clonal hematopoiesis accompanied by morphological dysplasia…”
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Genomic Analysis of Diffuse Large B Cell Lymphoma in a Japanese Cohort Using Targeted DNA Sequencing by Mishina, Tatsuzo, Oshima-Hasegawa, Nagisa, Tsukamoto, Shokichi, Fukuyo, Masaki, Kageyama, Hajime, Rahmutulla, Bahityar, Nagai, Yurie, Kayamori, Kensuke, Hino, Yutaro, Muto, Tomoya, Mitsukawa, Shio, Takeda, Yusuke, Mimura, Naoya, Ohwada, Chikako, Takeuchi, Masahiro, Tsujimura, Hideki, Iseki, Tohru, Nakaseko, Chiaki, Ikeda, Jun-ichiro, Itami, Makiko, Yokote, Koutaro, Ohara, Osamu, Kaneda, Atsushi, Sakaida, Emiko

“…Introduction: Recent studies based on next-generation sequencing revealed the genetic landscape of diffuse large B cell lymphoma (DLBCL). A new genetic…”
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