Search Results - "Nagai, Toshihiro"
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Disease-Modifying Effects of Lenvatinib, a Multiple Receptor Tyrosine Kinase Inhibitor, on Posttraumatic Osteoarthritis of the Knee
Published in International journal of molecular sciences (01-06-2024)“…Angiogenesis and vascular endothelial growth factor (VEGF) are involved in osteoarthritis (OA). We previously reported the inhibitory effect of bevacizumab in…”
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Therapeutic potential of appropriately evaluated safe-induced pluripotent stem cells for spinal cord injury
Published in Proceedings of the National Academy of Sciences - PNAS (13-07-2010)“…Various types of induced pluripotent stem (iPS) cells have been established by different methods, and each type exhibits different biological properties…”
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3
The orientation of a decellularized uterine scaffold determines the tissue topology and architecture of the regenerated uterus in rats
Published in Biology of reproduction (01-05-2019)“…A decellularized uterine scaffold (DUS) prepared from rats permits recellularization and regeneration of uterine tissues when placed onto a partially excised…”
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Cartilage repair in transplanted scaffold-free chondrocyte sheets using a minipig model
Published in Biomaterials (01-05-2012)“…Abstract Lacking a blood supply and having a low cellular density, articular cartilage has a minimal ability for self-repair. Therefore, wide-ranging cartilage…”
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5
Holocrine Secretion Occurs outside the Tight Junction Barrier in Multicellular Glands: Lessons from Claudin-1–Deficient Mice
Published in Journal of investigative dermatology (01-02-2020)“…Holocrine secretion is a specific mode of secretion involving secretion of entire cytoplasmic materials with remnants of dead cells, as observed in…”
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Isoform-specific mutation in Dystonin-b gene causes late-onset protein aggregate myopathy and cardiomyopathy
Published in eLife (09-08-2022)“…Dystonin ( DST ), which encodes cytoskeletal linker proteins, expresses three tissue-selective isoforms: neural DST-a, muscular DST-b, and epithelial DST-e…”
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The histone 3 lysine 9 methyltransferase inhibitor chaetocin improves prognosis in a rat model of high salt diet-induced heart failure
Published in Scientific reports (04-01-2017)“…Histone acetylation has been linked to cardiac hypertrophy and heart failure. However, the pathological implications of changes in histone methylation and the…”
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Large-Area Fluorescence and Electron Microscopic Correlative Imaging With Multibeam Scanning Electron Microscopy
Published in Frontiers in neural circuits (08-05-2019)“…Recent improvements in correlative light and electron microscopy (CLEM) technology have led to dramatic improvements in the ability to observe tissues and…”
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Evaluation of allowable time and histopathological changes in warm ischemia of the uterus in cynomolgus monkey as a model for uterus transplantation
Published in Acta obstetricia et gynecologica Scandinavica (01-09-2016)“…The objective of this study was to examine the allowable warm ischemic time and pathological changes due to ischemia and reperfusion injury in the uterus of…”
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10
Subclinical hypopigmentation of the skin and hair in a Japanese patient with Hermansky–Pudlak syndrome type 3
Published in Journal of dermatology (01-01-2020)Get full text
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11
Intravenous administration of anti-vascular endothelial growth factor humanized monoclonal antibody bevacizumab improves articular cartilage repair
Published in Arthritis research & therapy (01-01-2010)“…In this study, we investigate the efficacy of repairing an osteochondral defect in rabbit knee joints by administering bevacizumab, a humanized monoclonal…”
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12
Connectomics: comprehensive approaches for whole-brain mapping
Published in Microscopy (01-02-2015)“…The aim of connectomics analysis is to understand whole-brain neural connections. This is accomplished using new biotechnologies. Here, we provide an overview…”
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Somnolence and Dizziness During Mirogabalin Treatment in Patients With Neuropathic Pain Related to Lumbar Disease Who Switched From Pregabalin: A Retrospective Study
Published in Global spine journal (01-06-2023)“…Study Design: Multicenter retrospective study. Objectives: To investigate adverse events (AEs) in patients with neuropathic pain related to lumbar disease who…”
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14
H1foo Has a Pivotal Role in Qualifying Induced Pluripotent Stem Cells
Published in Stem cell reports (14-06-2016)“…Embryonic stem cells (ESCs) are a hallmark of ideal pluripotent stem cells. Epigenetic reprogramming of induced pluripotent stem cells (iPSCs) has not been…”
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Accumulation of secretory vesicles in the lacrimal gland epithelia is related to non-Sjögren's type dry eye in visual display terminal users
Published in PloS one (04-09-2012)“…Previous observations in a rat model of a non-Sjögren's syndrome (non-SS) type of dry eye seen in users of visual display terminals (VDT) indicated that…”
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Analysis of predisposing factors in elderly people with Type II odontoid fracture
Published in The spine journal (01-06-2014)“…Abstract Background context Type II odontoid fracture is the most frequent individual fracture in elderly people. An older person usually sustains a Type II…”
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Human telomerase reverse transcriptase and glucose-regulated protein 78 increase the life span of articular chondrocytes and their repair potential
Published in BMC musculoskeletal disorders (02-04-2012)“…Like all mammalian cells, normal adult chondrocytes have a limited replicative life span, which decreases with age. To facilitate the therapeutic use of…”
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18
In situ electric fields causing electro-stimulation from conductor contact of charged human
Published in Radiation protection dosimetry (01-08-2010)“…Contact currents flow from/into a human body when touching an object such as a metal structure with a different electric potential. These currents can…”
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Characteristics of a scaffold-free articular chondrocyte plate grown in rotational culture
Published in Tissue engineering. Part A (01-07-2008)“…We investigated whether articular chondrocytes could form three-dimensional tissue-engineered cartilage in a rotational culture system without a scaffold. A…”
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Vascular endothelial growth factor increases fenestral permeability in hepatic sinusoidal endothelial cells
Published in Liver international (01-12-2003)“…: Vascular endothelial growth factor (VEGF) is an important regulator of vasculogenesis and vascular permeability. Hepatic sinusoidal endothelial cells (SECs)…”
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