Search Results - "Nagai, Takako"

Linagliptin-Mediated DPP-4 Inhibition Ameliorates Kidney Fibrosis in Streptozotocin-Induced Diabetic Mice by Inhibiting Endothelial-to-Mesenchymal Transition in a Therapeutic Regimen by KANASAKI, Keizo, SEN SHI, KANASAKI, Megumi, JIANHUA HE, NAGAI, Takako, NAKAMURA, Yuka, ISHIGAKI, Yasuhito, KITADA, Munehiro, SWAYAM PRAKASH SRIVASTAVA, KOYA, Daisuke

“…Kidney fibrosis is the final common pathway of all progressive chronic kidney diseases, of which diabetic nephropathy is the leading cause…”
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Changes in Health-Related Quality of Life by Patient Education and Rehabilitation Based on a Behavior Change Program in Knee Osteoarthritis by Nagai, Takako, Uei, Hiroshi, Nakanishi, Kazuyoshi

“…The purpose of this study was to examine how rehabilitation and patient education for knee osteoarthritis improves health-related quality of life (HRQOL) and…”
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Functional prognosis in patients with sarcopenic dysphagia: An observational cohort study from the Japanese sarcopenic dysphagia database by Nagai, Takako, Wakabayashi, Hidetaka, Nishioka, Shinta, Momosaki, Ryo

“…Aim In sarcopenic dysphagia, confirmation of recovery of the swallowing function and activity of daily living is insufficient. The aim of this study was to…”
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Interactions of DPP-4 and integrin β1 influences endothelial-to-mesenchymal transition by Shi, Sen, Srivastava, Swayam Prakash, Kanasaki, Megumi, He, Jianhua, Kitada, Munehiro, Nagai, Takako, Nitta, Kyoko, Takagi, Susumu, Kanasaki, Keizo, Koya, Daisuke

“…Integrin β1 and dipeptidyl peptidase (DPP)-4 play roles in endothelial cell biology. Vascular endothelial growth factor (VEGF)-A inhibits…”
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Importance of early assessment and multioccupational interventions in sarcopenic dysphagia and aspiration pneumonia by Nagai, Takako, Wakabayashi, Hidetaka, Nishioka, Shinta, Momosaki, Ryo

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Association between board-certified physiatrist involvement and functional outcomes in sarcopenic dysphagia patients: a retrospective cohort study of the Japanese Sarcopenic Dysphagia Database by Nagai, Takako, Wakabayashi, Hidetaka, Nishioka, Shinta, Momosaki, Ryo

“…Objective: Dysphagia rehabilitation is an important area in geriatric nutrition due to the commonality of sarcopenic dysphagia in older adults. However, there…”
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FGFR1 is critical for the anti-endothelial mesenchymal transition effect of N-acetyl-seryl-aspartyl-lysyl-proline via induction of the MAP4K4 pathway by Li, Jinpeng, Shi, Sen, Srivastava, Swayam Prakash, Kitada, Munehiro, Nagai, Takako, Nitta, Kyoko, Kohno, Miyuki, Kanasaki, Keizo, Koya, Daisuke

“…Endothelial-to-mesenchymal transition (EndMT) has been shown to contribute to organ fibrogenesis, and we have reported that the anti-EndMT effect of N…”
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The Prevalence and Prognosis of Cachexia in Patients with Non-Sarcopenic Dysphagia: A Retrospective Cohort Study by Kakehi, Shingo, Wakabayashi, Hidetaka, Nagai, Takako, Nishioka, Shinta, Isono, Eri, Otsuka, Yukiko, Ninomiya, Junki, Momosaki, Ryo

“…The purpose of this study was to assess the prevalence and prognosis of cachexia in patients with non-sarcopenic dysphagia. A retrospective cohort study was…”
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Verification of phycological factors related to health-related quality of life in elderly knee osteoarthritis: A prospective cohort study by Nagai, Takako, Tsurusaki, Midori, Horaguchi, Takashi, Uei, Hiroshi, Nagaoka, Masahiro

“…In recent years, locomotive syndrome, which is a condition requiring nursing care due to musculoskeletal disease, has been reported, and interest in knee…”
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Effect of Antifibrotic MicroRNAs Crosstalk on the Action of N-acetyl-seryl-aspartyl-lysyl-proline in Diabetes-related Kidney Fibrosis by Srivastava, Swayam Prakash, Shi, Sen, Kanasaki, Megumi, Nagai, Takako, Kitada, Munehiro, He, Jianhua, Nakamura, Yuka, Ishigaki, Yasuhito, Kanasaki, Keizo, Koya, Daisuke

“…N-acetyl-seryl-aspartyl-lysyl-proline (AcSDKP) is an endogenous antifibrotic peptide. We found that suppression of AcSDKP and induction of dipeptidyl…”
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Influence of potentially inappropriate medications on activities of daily living for patients with osteoporotic vertebral compression fractures: A retrospective cohort study by Nagai, Takako, Wakabayashi, Hidetaka, Maeda, Keisuke, Momosaki, Ryo, Nishiyama, Ai, Murata, Hiroyasu, Uei, Hiroshi

“…Potentially inappropriate medications (PIMs) are a major concern in geriatric care. Osteoporotic vertebral compression fractures (OVCFs) are more common among…”
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Relationship Between Start of Feeding and Functional Outcome in Aspiration Pneumonia: A Retrospective Cohort Study by Nagai, Takako, Uei, Hiroshi, Nakanishi, Kazuyoshi

“…Introduction Aspiration pneumonia is the predominant form of pneumonia in the elderly. Low oral intake levels and malnutrition have been reported to be…”
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N-acetyl-seryl-aspartyl-lysyl-proline Inhibits Diabetes-Associated Kidney Fibrosis and Endothelial-Mesenchymal Transition by Nagai, Takako, Kanasaki, Megumi, Srivastava, Swayam Prakash, Nakamura, Yuka, Ishigaki, Yasuhito, Kitada, Munehiro, Shi, Sen, Kanasaki, Keizo, Koya, Daisuke

“…Endothelial-to-mesenchymal transition (EndMT) emerges as an important source of fibroblasts. MicroRNA let-7 exhibits anti-EndMT effects and fibroblast growth…”
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Nutrition status and functional prognosis among elderly patients with distal radius fracture: a retrospective cohort study by Nagai, Takako, Tanimoto, Koji, Tomizuka, Yoshiaki, Uei, Hiroshi, Nagaoka, Masahiro

“…Distal radius fractures (DRF) are common in the elderly and are typically caused falls. Malnutrition has also been identified as a poor prognostic factor in…”
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Relationship between potentially inappropriate medications and functional prognosis in elderly patients with distal radius fracture: a retrospective cohort study by Nagai, Takako, Nagaoka, Masahiro, Tanimoto, Koji, Tomizuka, Yoshiaki, Uei, Hiroshi, Nakanishi, Kazuyoshi

“…Potentially inappropriate medications (PIMs) are a major concern in geriatric care. PIMs increase the risk of falls in elderly patients. However, the…”
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Oral Administration of N-Acetyl-seryl-aspartyl-lysyl-proline Ameliorates Kidney Disease in Both Type 1 and Type 2 Diabetic Mice via a Therapeutic Regimen by Koya, Daisuke, Kanasaki, Keizo, Srivastava, Swayam Prakash, Kitada, Munehiro, Kanasaki, Megumi, Nagai, Takako, Shi, Sen, Nitta, Kyoko, Haneda, Masakazu

“…Kidney fibrosis is the final common pathway of progressive kidney diseases including diabetic nephropathy. Here, we report that the endogenous antifibrotic…”
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N-Acetyl-seryl-aspartyl-lysyl-proline is a potential biomarker of renal function in normoalbuminuric diabetic patients with eGFR ≥ 30 ml/min/1.73 m2 by Nitta, Kyoko, Nagai, Takako, Mizunuma, Yuiko, Kitada, Munehiro, Nakagawa, Atsushi, Sakurai, Masaru, Toyoda, Masao, Haneda, Masakazu, Kanasaki, Keizo, Koya, Daisuke

“…Background A biomarker, by which we can predict alterations of renal function in normoalbuminuric diabetic patients, is not available. Here, we report that…”
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The biological significance of angiotensin-converting enzyme inhibition to combat kidney fibrosis by Nagai, Takako, Nitta, Kyoko, Kanasaki, Megumi, Koya, Daisuke, Kanasaki, Keizo

“…Both angiotensin-converting enzyme inhibitor (ACE-I) and angiotensin II receptor blocker have been recognized as renin–angiotensin system (RAS) inhibitors…”
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Restoration of the Hypothalamic-pituitary-adrenal Response to Hypoglycemia in Type 2 Diabetes by Avoiding Chronic Hypoglycemia by Tsuda, Shin-ichi, Konishi, Kazunori, Otoda, Toshiki, Nagai, Takako, Takeda-Watanabe, Ai, Kanasaki, Megumi, Kitada, Munehiro, Nakagawa, Atsushi, Nishizawa, Makoto, Kanasaki, Keizo, Koya, Daisuke

“…An impaired ability to sense and respond to drug-induced hypoglycemia is a common and serious complication in diabetic patients. The…”
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Elevation of the antifibrotic peptide N-acetyl-seryl-aspartyl-lysyl-proline: a blood pressure-independent beneficial effect of angiotensin I-converting enzyme inhibitors by Kanasaki, Megumi, Nagai, Takako, Kitada, Munehiro, Koya, Daisuke, Kanasaki, Keizo

“…Blockade of the renin-angiotensin system (RAS) is well recognized as an essential therapy in hypertensive, heart, and kidney diseases. There are several…”
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