Search Results - "Nagai, Maria A."

In silico analyses identify lncRNAs: WDFY3-AS2, BDNF-AS and AFAP1-AS1 as potential prognostic factors for patients with triple-negative breast tumors by Rodrigues de Bastos, Daniel, Nagai, Maria A

“…Long non-coding RNAs (lncRNAs) are characterized as having 200 nucleotides or more and not coding any protein, and several been identified as differentially…”
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PIK3CA exon 20 mutations are associated with poor prognosis in breast cancer patients by Mangone, Flavia R., Bobrovnitchaia, Irina G., Salaorni, Sibeli, Manuli, Erika, Nagai, Maria A.

“…The phosphatidylinositol 3-kinase/AKT axis is an important cell-signaling pathway that mediates cell proliferation and survival, two biological processes that…”
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Decreased expression of ADAMTS-1 in human breast tumors stimulates migration and invasion by Freitas, Vanessa M, do Amaral, Jônatas Bussador, Silva, Thaiomara A, Santos, Emerson S, Mangone, Flávia R, Pinheiro, João de Jesus, Jaeger, Ruy G, Nagai, Maria A, Machado-Santelli, Gláucia Maria

“…ADAMTS-1 (a disintegrin and metalloprotease with thrombospondin motifs) is a member of the ADAMTS family of metalloproteases. Here, we investigated mRNA and…”
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Prognostic and predictive value of Pleckstrin homology-like domain, family A family members in breast cancer by R Mangone, Flavia, Av Valoyes, Maira, G do Nascimento, Renan, Pf Conceição, Mércia, R Bastos, Daniel, C Pavanelli, Ana, C Soares, Iberê, S de Mello, Evandro, Nonogaki, Suely, Ab de T Osório, Cynthia, A Nagai, Maria

“…The (pleckstrin homology like domain, family A) gene family encodes proteins capable of inhibiting AKT (serine/threonine kinase) signaling through…”
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Abnormal Long Non-Coding RNAs Expression Patterns Have the Potential Ability for Predicting Survival and Treatment Response in Breast Cancer by Pavanelli, Ana Carolina, Mangone, Flavia Rotea, Barros, Luciana R C, Machado-Rugolo, Juliana, Capelozzi, Vera L, Nagai, Maria A

“…Abnormal long non-coding RNAs (lncRNAs) expression has been documented to have oncogene or tumor suppressor functions in the development and progression of…”
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Apoptotic signaling in salivary mucoepidermoid carcinoma by Silva, Gabriela M., Saavedra, Victoria, Ianez, Renata C. F., Sousa, Elen A., Gomes, Ágatha N., Kelner, Natalie, Nagai, Maria A., Kowalski, Luiz P., Soares, Fernando A., Lourenço, Silvia V., Coutinho‐Camillo, Cláudia M.

“…Background Mucoepidermoid carcinoma is the most common malignant tumor of salivary glands. Apoptosis plays an important role in organogenesis of glandular…”
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Prostate apoptosis response-4 is involved in the apoptosis response to docetaxel in MCF-7 breast cancer cells by PEREIRA, MICHELLY C, DE BESSA-GARCIA, SIMONE A, BURIKHANOV, RAVSHAN, PAVANELLI, ANA CAROLINA, ANTUNES, LOURIVAL, RANGNEKAR, VIVEK M, NAGAI, MARIA A

“…Experimental evidence indicates that prostate apoptosis response-4 (Par-4, also known as PAWR) is a key regulator of cancer cell survival and may be a target…”
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Genetic alterations in juvenile nasopharyngeal angiofibromas by Coutinho-Camillo, Cláudia M., Brentani, M. Mitzi, Nagai, Maria A.

“…Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign neoplasm of the nasopharynx that accounts for 0.5% of all head and neck tumors. Although…”
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Relaxation of imprinting of IGFII gene in juvenile nasopharyngeal angiofibromas by Coutinho-Camillo, Cláudia M, Brentani, M Mitzi, Butugan, Ossamu, Torloni, Humberto, Nagai, Maria A

“…IGFII and H19 genes are expressed only from one allele due to genomic imprinting, biallelic expression (loss of imprinting) being associated with the…”
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Insulin-like growth factor-1 and 17β-estradiol down-regulate prostate apoptosis response-4 expression in MCF-7 breast cancer cells by Casolari, Debora, Pereira, Michelly, de Bessa Garcia, Simone, Nagai, Maria

“…The PKC apoptosis WT1 regulator gene, also named prostate apoptosis response-4 (PAR-4), encodes a pro-apoptotic protein that sensitizes cells to numerous…”
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Silencing of LRRC49 and THAP10 genes by bidirectional promoter hypermethylation is a frequent event in breast cancer by DE SOUZA SANTOS, Emerson, DE BESSA, Simone A, NETTO, Mario M, NAGAI, Maria A

“…Previously we found that levels of LRRC49 (leucine rich repeat containing 49; FLJ20156) transcripts were elevated in ER-positive breast tumors compared with…”
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Analysis of PTEN and the 10q23 region in primary prostate carcinomas by FEILOTTER, H. E, NAGAI, M. A, BOAG, A. H, ENG, C, MULLIGAN, L. M

“…Deletions involving chromosome 10q23 occur frequently in prostatic carcinomas. Recently, a novel tumour suppressor gene, PTEN, mapping to this interval, has…”
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Expression Pattern of the Pro-apoptotic Gene PAR-4 During the Morphogenesis of MCF-10A Human Mammary Epithelial Cells by de Bessa Garcia, Simone A., Pereira, Michelly C., Nagai, Maria A.

“…The histological organization of the mammary gland involves a spatial interaction of epithelial and myoepithelial cells with the specialized basement membrane…”
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Differentially expressed genes in the prostate cancer cell line LNCaP after exposure to androgen and anti-androgen by Coutinho-Camillo, Cláudia M., Salaorni, Sibeli, Sarkis, Álvaro S., Nagai, Maria A.

“…Androgens play an important role in growth and maintenance of prostate cells. The actions of androgens are mediated by the androgen receptor (AR), a…”
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Abstract P2-17-02: SMC6 down-regulation: marker of genetic instability and poor outcome in breast cancer by Mangone, Flavia R. Rotea, Krepischi, Ana Cristina V., Carraro, Dirce M., Nagai, Maria A.

“…Genetic instability commonly found in tumors may be a consequence of imbalance in homologous recombination (HR), a mechanism of DNA double-strand break (DSB)…”
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Abstract 3803: Transcriptome analysis of MCF7 breast cancer cells with different expression profile of PAR-4 (prostate apoptosis response-4) in the presence and absence of docetaxel by de Bessa Garcia, Simone A., Pavanelli, Ana C., Melo, Natalia C., Nagai, Maria A.

“…The ability of cancer cells to evade apoptosis is one of the essential alterations in cell physiology that dictate tumor growth and impact chemo- and…”
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Androgen receptor CAG repeat polymorphism in prostate cancer from a Brazilian population by Santos, Mariana L.dos, Sarkis, Álvaro S, Nishimoto, Inês N, Nagai, Maria A

“…Shorter CAG repeats in the androgen receptor ( AR) gene have been associated with increased prostate cancer risk. Aiming to investigate whether the AR CAG…”
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Abstract 242: Evaluation of apoptosis-related microRNAs in salivary gland tumors by Flores, Bianca T., Lourenço, Silvia V., Nagai, Maria A., Kowalski, Luiz Paulo, Soares, Fernando A., Coutinho-Camillo, Cláudia

“…MicroRNAs (miRNAs) are a class of short non-coding RNAs that regulates gene expression post-transcriptionally, being important modulators of several cellular…”
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Abstract 2887: Regulation of PAR-4 and PHLDA1 expression by estrogen and epidermal growth factor in MCF-7 breast cancer cells by de Bessa-Garcia, Simone A., Pereira, Michelly C., Nagai, Maria A.

“…Crosstalk between the estrogens and growth factor signaling pathways has been associated with proliferation and survival of breast cancer cells and resistance…”
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Abstract A50: PAR-4 (prostate apoptosis response-4) modulates cell survival and chemosensitivity to docetaxel in MCF-7 breast cancer cells by Pereira, Michelly C., Bessa-Garcia, Simone A. de, Nagai, Maria A.

“…PAWR (PKC apoptosis WT1 regulator) also known as prostate apoptosis response-4 (PAR-4) was first identified in prostate cancer cells undergoing apoptosis. It…”
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