Search Results - "Nagahama, Kenji"

Animal Model of Acid-Reflux Esophagitis : Pathogenic Roles of Acid/Pepsin, Prostaglandins, and Amino Acids by Takeuchi, Koji, Nagahama, Kenji

“…Esophagitis was induced in rats within 3 h by ligating both the pylorus and transitional region between the forestomach and glandular portion under ether…”
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Orally administered L-arginine and glycine are highly effective against acid reflux esophagitis in rats by Nagahama, Kenji, Nishio, Hikaru, Yamato, Masanori, Takeuchi, Koji

“…Reflux esophagitis is caused mainly by excessive exposure of the mucosa to gastric contents. In the present study, we examined the effect of several amino…”
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Protective Effect of Lafutidine, a Novel H2-Receptor Antagonist, on Reflux Esophagitis in Rats Through Capsaicin-Sensitive Afferent Neurons by Nagahama, Kenji, Yamato, Masanori, Kato, Shinichi, Takeuchi, Koji

“…We examined the effect of lafutidine, a novel histamine H2-receptor antagonist, on acid reflux esophagitis in rats in relation to capsaicin-sensitive afferent…”
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Biphasic effect of prostaglandin E2 in a rat model of esophagitis mediated by EP1 receptors: relation to pepsin secretion by Yamato, Masanori, Nagahama, Kenji, Kotani, Tohru, Kato, Shinichi, Takeuchi, Koji

“…We investigated the roles of prostaglandin (PG) E2 and cyclooxygenase (COX) isoenzymes in the mucosal defense of the esophagus, using subtype-selective EP…”
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Z-505, an Oral Ghrelin Receptor Agonist, Attenuates Anorexia After Total Gastrectomy in Rats by Shiomi, Yoshihiro, Yoshimura, Makoto, Hori, Yuko, Ohira, Yuta, Nagahama, Kenji, Ozaki, Tomoko, Takei, Mineo, Tanaka, Takao, Uno, Tomohide

“…Anorexia is a serious problem in patients with gastric cancer who have undergone gastrectomy. Ghrelin, an orexigenic hormone primarily secreted from the…”
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Acotiamide (Z-338), a Novel Gastroprokinetic Agent for the Treatment of Functional Dyspepsia, Enhances Gastric Motility Without Prolonging QT Interval in Dogs and Rats by Matsunaga, Yugo, Tanaka, Takao, Kawachi, Masanao, Nagahama, Kenji, Ito, Katsunori, Hori, Yuko, Eta, Runa, Takei, Mineo

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Essential role of pepsin in pathogenesis of acid reflux esophagitis in rats by NAGAHAMA, Kenji, YAMATO, Masanori, NISHIO, Hikaru, TAKEUCHI, Koji

“…Pepsin, a protease activated by gastric acid, is a component of the refluxate, yet the role of pepsin in the pathogenesis of reflux esophagitis has not been…”
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Acotiamide hydrochloride (Z-338) enhances gastric motility and emptying by inhibiting acetylcholinesterase activity in rats by Kawachi, Masanao, Matsunaga, Yugo, Tanaka, Takao, Hori, Yuko, Ito, Katsunori, Nagahama, Kenji, Ozaki, Tomoko, Inoue, Naonori, Toda, Ryoko, Yoshii, Kazuyoshi, Hirayama, Masamichi, Kawabata, Yoshihiro, Takei, Mineo

“…In clinical trials, acotiamide hydrochloride (acotiamide: Z-338) has been reported to be useful in the treatment of functional dyspepsia. Here, we investigated…”
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Protective effect of lafutidine, a novel histamine H2-receptor antagonist, on acid reflux esophagitis in rats through capsaicin-sensitive afferent neurons by Nagahama, Kenji, Kato, Shinichi, Yamato, Masanori, Takeuchi, Koji

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Dual action of prostaglandin E2 on gastric acid secretion through different EP receptor subtypes in rats by Shinichi Kato, Masanori Yamato, Kenji Nagahama, Koji Takeuchi

“…We examined the role of prostaglandin (PG) EP receptor subtypes in regulation of gastric acid secretion in rats. Acid secretion was measured by pH-stat method…”
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Importance of pepsin in the pathogenesis of acid reflux esophagitis by Masanori Yamato, Kenji Nagahama, Shinichi Kato, Koji Takeuchi

“…The role of pepsin in the pathogenesis of acid reflux esophagitis was investigated in rats. The reflux esophagitis was induced by ligating both the pylorus and…”
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Protective Effect of Lafutidine, a Novel H2-Receptor Antagonist, on Reflux Esophagitis in Rats Through Capsaicin-Sensitive Afferent Neurons by Nagahama, Kenji, Yamato, Masanori, Kato, Shinichi, Takeuchi, Koji

“…We examined the effect of lafutidine, a novel histamine H2-receptor antagonist, on acid reflux esophagitis in rats in relation to capsaicin-sensitive afferent…”
Get full text

Protective Effect of Lafutidine, a Novel H sub(2)-Receptor Antagonist, on Reflux Esophagitis in Rats Through Capsaicin-Sensitive Afferent Neurons by Nagahama, Kenji, Yamato, Masanori, Kato, Shinichi, Takeuchi, Koji

“…We examined the effect of lafutidine, a novel histamine H sub(2)-receptor antagonist, on acid reflux esophagitis in rats in relation to capsaicin- sensitive…”
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Measurement and correlation of the swelling pressure of N-isopropylacrylamide gel by Inomata, Hiroshi, Nagahama, Kenji, Saito, Shozaburo

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