Search Results - "Naga, Osama S."
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A Quantitative Increase in Regulatory T Cells Controls Development of Vitiligo
Published in Journal of investigative dermatology (01-05-2014)“…T-cell cytolytic activity targeting epidermal melanocytes is shown to cause progressive depigmentation and autoimmune vitiligo. By using the recently developed…”
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Promoting thiol expression increases the durability of antitumor T-cell functions
Published in Cancer research (Chicago, Ill.) (01-11-2014)“…Ex vivo-expanded CD8(+) T cells used for adoptive immunotherapy generally acquire an effector memory-like phenotype (TEM cells). With regard to therapeutic…”
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Estrogen Receptor α Deficiency Modulates TLR Ligand-Mediated PDC-TREM Expression in Plasmacytoid Dendritic Cells in Lupus-Prone Mice
Published in The Journal of immunology (1950) (15-12-2015)“…Female lupus-prone NZM2410 estrogen receptor α (ERα)-deficient mice are protected from renal disease and have prolonged survival compared with wild-type…”
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Estrogen receptor alpha modulates toll-like receptor signaling in murine lupus
Published in Clinical immunology (Orlando, Fla.) (01-07-2012)“…Abstract Systemic lupus erythematosus (SLE) is a disease that disproportionately affects females. Despite significant research effort, the mechanisms…”
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T cells expanded in presence of IL-15 exhibit increased antioxidant capacity and innate effector molecules
Published in Cytokine (Philadelphia, Pa.) (01-08-2011)“…► IL-15 treated T cells have increased cell-surface thiols, intracellular glutathione, and thioredoxins. ►IL-15 treated T cells have upregulated anti-oxidants…”
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Inhibition of superoxide generation upon T-cell receptor engagement rescues Mart-1(27-35)-reactive T cells from activation-induced cell death
Published in Cancer research (Chicago, Ill.) (01-08-2009)“…Cytotoxic T lymphocytes (CTL) may undergo massive expansion upon appropriate antigenic stimulation. Homeostasis is maintained by a subsequent "contraction" of…”
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Inhibition of Superoxide Generation upon T-Cell Receptor Engagement Rescues Mart-127-35-Reactive T Cells from Activation-Induced Cell Death
Published in Cancer research (Chicago, Ill.) (01-08-2009)“…Cytotoxic T lymphocytes (CTL) may undergo massive expansion upon appropriate antigenic stimulation. Homeostasis is maintained by a subsequent “contraction” of…”
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Inhibition of Superoxide Generation upon TCR Engagement Rescues Mart-127-35 reactive T cells from Activation Induced Cell Death
Published in Cancer research (Chicago, Ill.) (28-07-2009)“…Cytolytic T lymphocytes (CTL) undergo massive expansion upon appropriate antigenic stimulation. Homeostasis is maintained by a subsequent “contraction” of…”
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Development of a transgenic mouse with high affinity TCR reactive to human tyrosinase epitope (41.39)
Published in The Journal of immunology (1950) (01-04-2009)“…Most tumor-associated antigen epitopes recognized on human melanomas by autologous T lymphocytes are derived from nonmutated self-proteins. Given the belief…”
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