Search Results - "Naeve, Gregory S"
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Fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) distribution in spinal cord and dorsal root ganglia under basal and neuropathic pain conditions
Published in The European journal of neuroscience (01-09-2004)“…Fractalkine is a unique chemokine reported to be constitutively expressed by neurons. Its only receptor, CX3CR1, is expressed by microglia. Little is known…”
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Neuritin: A Gene Induced by Neural Activity and Neurotrophins that Promotes Neuritogenesis
Published in Proceedings of the National Academy of Sciences - PNAS (18-03-1997)“…Neural activity and neurotrophins induce synaptic remodeling in part by altering gene expression. A cDNA encoding a glycosylphoshatidylinositol-anchored…”
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Potent imidazole and triazole CB1 receptor antagonists related to SR141716
Published in Bioorganic & medicinal chemistry letters (08-03-2004)“…Diarylimidazolecarboxamides and diaryltriazolecarboxamides related to SR141716 were synthesized and tested for binding to the human CB(1) receptor. Suitably…”
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Identification of differentially expressed genes induced by transient ischemic stroke
Published in Brain research. Molecular brain research. (30-05-2002)“…We have used a rat model of focal cerebral ischemia to investigate changes in gene expression that occur during stroke. To monitor these changes, we employed…”
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Neuroprotective Effects of Insulin-Like Growth Factor-Binding Protein Ligand Inhibitors in Vitro and in Vivo
Published in Journal of cerebral blood flow and metabolism (01-10-2003)“…The role of brain insulin-like growth factors (IGFs) and IGF binding proteins (IGFBPs) in neuroprotection was further investigated using in vitro and in vivo…”
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Potent imidazole and triazole CB 1 receptor antagonists related to SR141716
Published in Bioorganic & medicinal chemistry letters (01-03-2004)Get full text
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Expression of rat insulin-like growth factor binding protein-6 in the brain, spinal cord, and sensory ganglia
Published in Brain research. Molecular brain research. (22-02-2000)“…Insulin-like growth factors (IGFs) are important trophic factors during development as well as in the adult or damaged nervous system. Their trophic actions…”
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Temporal events regulating the early phases of the mammalian cell cycle
Published in Current opinion in cell biology (01-04-1991)“…It is proposed that the regulation of the pathways directing mammalian cell cycle progression involves several oncogenes. A summary of what is known about some…”
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Temporal regulation of cyclin A-p107 and p33(cdk2) complexes binding to a human thymidine kinase promoter element important for G(1)-S phase transcriptional regulation
Published in Proceedings of the National Academy of Sciences - PNAS (15-04-1993)“…The cyclins are an extensive family of proteins whose cell cycle-dependent synthesis is postulated to control multiple events during the cell cycle, and in…”
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Temporal Regulation of Cyclin A-p107 and p33cdk2Complexes Binding to a Human Thymidine Kinase Promoter Element Important for G1-S Phase Transcriptional Regulation
Published in Proceedings of the National Academy of Sciences - PNAS (15-04-1993)“…The cyclins are an extensive family of proteins whose cell cycle-dependent synthesis is postulated to control multiple events during the cell cycle. The…”
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Identification of a 68 kDa protein species as a specific DNA-binding component of the H3abp complex interacting with the histone H3.2 G1/S regulatory domain
Published in Nucleic acids research (11-02-1995)“…The hamster histone H3.2 promoter contains a protein binding site (referred to as site X) required for G1/S transcriptional activation. We report here that…”
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A phase 1a clinical trial of LYM-1 monoclonal antibody serotherapy in patients with refractory B cell malignancies
Published in Hematological oncology (01-03-1989)“…Ten patients with refractory B cell lymphomas were treated with weekly intravenous infusions of escalating doses of murine monoclonal antibody (MoAb) LYM-1…”
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Immunohistochemical Characterization of a 183 KD Myeloid-Specific–DNA-Binding Protein in B5 Fixed, Paraffin-Embedded Tissues, and Bone Marrow Aspirates by Monoclonal Antibody BM-1
Published in Blood (01-10-1987)“…A monoclonal antibody, designated BM-1, which is reactive in B5 formalin-fixed, paraffin-embedded tissues, has been generated against a cytoplasmic and nuclear…”
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Daunomycin and doxorubicin Lym-1-drug conjugates for the treatment of malignant lymphomas
Published in Cancer treatment and research (1989)Get more information
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Immunologic and biochemical analysis of TNT-1 and TNT-2 monoclonal antibody binding to histones
Published in Hybridoma (01-12-1993)“…Two novel murine monoclonal antibodies that bind to intracellular antigens, designated TNT-1 and TNT-2, have been generated by immunizing mice with nuclear…”
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