Search Results - "Nadir, Yona"

Augmented Degradation of Factors VIII and IX in the Intermittent Movement State by Cohen, Haim, Keren-Politansky, Anat, Crispel, Yonatan, Yanovich, Chen, Asayag, Keren, Nadir, Yona

“…The most common clinical presentation of hemophilia A and hemophilia B is bleeding in large joints and striated muscles. It is unclear why bleeding has a…”
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Dehydration as a Possible Cause of Monthly Variation in the Incidence of Venous Thromboembolism by Elias, Saad, Hoffman, Ron, Saharov, Gleb, Brenner, Benjamin, Nadir, Yona

“…Monthly or seasonal changes in the incidence of venous thromboembolism (VTE) were previously reported; however, the mechanism of such variability is not…”
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Heparanase and coagulation-new insights by Nadir, Yona

“…Heparanase, a β-D-endoglucuronidase abundant in platelets that was discovered 30 years ago, is an enzyme that cleaves heparan sulfate side chains on the cell…”
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Calcium Prevents Enhanced Degradation of Factor VIII in the Condition of Motion by Cohen, Haim, Keren-Politansky, Anat, Crispel, Yonatan, Yanovich, Chen, Asayag, Keren, Nadir, Yona

“…Background: Hemophilia A and B induce recurrent bleeding episodes, mainly in skeletal muscles and joints that are in intermittent motion. We have previously…”
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Circulating heparan sulfate chains and body weight contribute to anti-Xa levels in cancer patients using the prophylactic dose of enoxaparin by Maurice-Dror, Corinne, Litvak, Michael, Keren-Politansky, Anat, Ackerman, Shanny, Haim, Nissim, Nadir, Yona

“…Hospitalized cancer patients are at increased risk of thrombosis and prophylaxis with heparin is recommended. Heparanase is a protein capable of degrading…”
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Cancer and Thrombosis-New Insights by Nadir, Yona, Brenner, Benjamin

“…Cancer patients have a pro-thrombotic state attributed to the ability of cancer cells to activate the coagulation system and interact with hemostatic cells,…”
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Heparanase enhances the generation of activated factor X in the presence of tissue factor and activated factor VII by NADIR, Yona, BRENNER, Benjamin, FUX, Liat, SHAFAT, Itay, ATTIAS, Judith, VLODAVSKY, Israel

“…Heparanase is an endo-β-D-glucuronidase dominantly involved in tumor metastasis and angiogenesis. Recently, we demonstrated that heparanase is involved in the…”
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Pregnancy and non-pregnancy related immune thrombotic thrombocytopenic purpura in women of reproductive age by Rottenstreich, Amihai, Dor, Shira, Keren-Politansky, Anat, Sarig, Galit, Nadir, Yona, Ellis, Martin, Spectre, Galia, Kirgner, Ilya, Pikovsky, Oleg, Arad, Ariela, Dann, Eldad J., Kalish, Yosef

“…Pregnancy is a precipitating factor for immune thrombotic thrombocytopenic purpura (iTTP). We compared the clinical course and outcomes of iTTP in women of…”
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Heparanase induces tissue factor pathway inhibitor expression and extracellular accumulation in endothelial and tumor cells by Nadir, Yona, Brenner, Benjamin, Gingis-Velitski, Sveta, Levy-Adam, Flonia, Ilan, Neta, Zcharia, Eyal, Nadir, Erez, Vlodavsky, Israel

“…Heparanase activity is implicated in cell invasion, tumor metastasis and angiogenesis. Recently, we have reported that heparanase stimulates tissue factor (TF)…”
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An ELISA method for the detection and quantification of human heparanase by Shafat, Itay, Zcharia, Eyal, Nisman, Benjamin, Nadir, Yona, Nakhoul, Farid, Vlodavsky, Israel, Ilan, Neta

“…Heparanase is a mammalian endo-β- d-glucuronidase that cleaves heparan sulfate side chains at a limited number of sites. Heparanase enzymatic activity is…”
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The endothelial tumor suppressor p53 is essential for venous thrombus formation in aged mice by Bochenek, Magdalena L., Bauer, Tobias, Gogiraju, Rajinikanth, Nadir, Yona, Mann, Amrit, Schönfelder, Tanja, Hünig, Leonie, Brenner, Benjamin, Münzel, Thomas, Wenzel, Philip, Konstantinides, Stavros, Schäfer, Katrin

“…Venous thromboembolism (VTE) is a leading cause of morbidity and mortality in elderly people. Increased expression of tumor suppressor protein 53 (p53) has…”
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Decreasing Tumor Growth and Angiogenesis by Inhibition of Coagulation by Nadir, Yona

“…Data regarding the effect of coagulation proteins on enhancing angiogenesis and tumor growth are ample. Thus, inhibition of the coagulation system in an…”
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Heparanase coagulation and cancer progression by Nadir, Yona, MD, PhD, Brenner, Benjamin, MD

“…Heparanase is an endo-β-D-glucuronidase capable of cleaving heparan sulphate (HS) side chains of heparan sulphate proteoglycans on cell surfaces and the…”
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Heparanase, heparin and the coagulation system in cancer progression by Vlodavsky, Israel, Ilan, Neta, Nadir, Yona, Brenner, Benjamin, Katz, Ben-Zion, Naggi, Annamaria, Torri, Giangiacomo, Casu, Benito, Sasisekharan, Ram

“…Abstract Heparanase is an endoglycosidase which cleaves heparan sulfate (HS) and hence participates in degradation and remodeling of the extracellular matrix…”
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Heparanase-A Link between Coagulation, Angiogenesis, and Cancer by Nadir, Yona, Brenner, Benjamin

“…Heparanase that was cloned from and is abundant in the placenta is implicated in cell invasion, tumor metastasis, and angiogenesis. Recently we have…”
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Hemostatic and Nonhemostatic Effects of Heparan Sulfate Proteoglycans by Nadir, Yona, Lisman, Ton

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Heparanase multiple effects in cancer by Nadir, Yona, Brenner, Benjamin

“…ABSTRACT Heparanase is an endo-β-D-glucuronidase that is capable of cleaving heparan sulfate side chains of heparan sulfate proteoglycans on cell surfaces and…”
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Heparanase procoagulant activity in cancer progression by Nadir, Yona, Brenner, Benjamin

“…ABSTRACT Heparanase is an endo-β-D-glucuronidase that is capable of cleaving heparan sulfate side chains of heparan sulfate proteoglycans on cell surfaces and…”
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Novel strategies of coagulation inhibition for reducing tumor growth and angiogenesis by Nadir, Yona, Brenner, Benjamin

“…Activated proteins of the coagulation system are known to enhance angiogenesis and tumor growth. Notably, the main coagulation proteins involved are those of…”
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Progestin type affects the increase of heparanase level and procoagulant activity mediated by the estrogen receptor by Treger, Sharon, Ackerman, Shanny, Kaplan, Victoria, Ghanem, Shourouk, Nadir, Yona

“…Abstract STUDY QUESTION Does progestin have an effect on heparanase level and procoagulant activity? SUMMARY ANSWER Progestin increases the heparanase level…”
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