Search Results - "Nadin, Silvina B"
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Heat shock proteins and DNA repair mechanisms: an updated overview
Published in Cell stress & chaperones (01-05-2018)“…Heat shock proteins (HSPs), also known as molecular chaperones, participate in important cellular processes, such as protein aggregation, disaggregation,…”
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Genomic effects of a nanostructured alumina insecticide in human peripheral blood lymphocytes in vitro
Published in Heliyon (01-06-2020)“…Nanotechnology is providing new tools for precision agriculture, such as agrochemical agents and innovative delivery mechanisms to improve cropping efficiency…”
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A Silver Staining Method for Single-cell Gel Assay
Published in The journal of histochemistry and cytochemistry (01-09-2001)“…The single-cell gel assay (comet assay) is a very useful microelectrophoretic technique for evaluation of DNA damage and repair in individual cells. Usually,…”
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Relevance of Comet Assay and Phosphorylated-Hsp90α in Cancer Patients’ Peripheral Blood Leukocytes as Tools to Assess Cisplatin-based Chemotherapy Clinical Response and Disease Outcome
Published in The journal of histochemistry and cytochemistry (01-03-2024)“…Cisplatin (cPt) is a commonly used treatment for solid tumors. The main target of its cytotoxicity is the DNA molecule, which makes the DNA damage response…”
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Circulating heat shock protein 27 (HSPB1) levels in prediction of pre‐eclampsia: A pilot study
Published in International journal of gynecology and obstetrics (01-07-2022)“…Objective To determine whether circulating heat shock proteins HSP27/HSPB1 and HSP90α/HSPC1 may be useful for early prediction of the occurrence of…”
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DNA Damage Repair Proteins, HSP27, and Phosphorylated-HSP90α as Predictive/Prognostic Biomarkers of Platinum-based Cancer Chemotherapy: An Exploratory Study
Published in Applied immunohistochemistry & molecular morphology (01-07-2022)“…Platinum analogs are commonly used for cancer treatment. There is increasing interest in finding biomarkers which could predict and overcome resistance,…”
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TP73 DNA methylation and upregulation of ΔNp73 are associated with an adverse prognosis in breast cancer
Published in Journal of clinical pathology (01-01-2018)“…Accumulated evidence suggests that aberrant methylation of the gene and increased levels of ΔNp73 in primary tumours correlate with poor prognosis. However,…”
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Hyperthermia effects on Hsp27 and Hsp72 associations with mismatch repair (MMR) proteins and cisplatin toxicity in MMR-deficient/proficient colon cancer cell lines
Published in International journal of hyperthermia (04-07-2015)“…Hyperthermia is used in combination with conventional anticancer agents to potentiate their cytotoxicity. One of its key events is the synthesis of heat shock…”
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Prognostic implication of HSPA (HSP70) in breast cancer patients treated with neoadjuvant anthracycline-based chemotherapy
Published in Cell stress & chaperones (01-07-2014)“…Neoadjuvant chemotherapy is used in patients with locally advanced breast cancer to reduce tumor size before surgery. Unfortunately, resistance to chemotherapy…”
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Effects of hyperthermia on Hsp27 (HSPB1), Hsp72 (HSPA1A) and DNA repair proteins hMLH1 and hMSH2 in human colorectal cancer hMLH1-deficient and hMLH1-proficient cell lines
Published in International journal of hyperthermia (01-05-2012)“…The objective of the present study was to examine the consequences of a mild hyperthermia in human tumour cell lines deficient and proficient in the DNA…”
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Prognostic value of Bcl-2 in breast cancer patients treated with neoadjuvant anthracycline based chemotherapy
Published in Molecular oncology (01-06-2008)“…We have analyzed the predictive/prognostic value of Bcl-2 protein in breast cancer patients treated with neoadjuvant chemotherapy. One hundred and ten patients…”
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Deoxyribonucleic acid damage induced by doxorubicin in peripheral blood mononuclear cells: possible roles for the stress response and the deoxyribonucleic acid repair process
Published in Cell stress & chaperones (01-12-2003)“…Doxorubicin is an antineoplastic drug widely used in cancer treatment. However, many tumors are intrinsically resistant to the drug or show drug resistance…”
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13
DNA Damage Repair Proteins, HSP27, and Phosphorylated-HSP90α as Predictive/Prognostic Biomarkers of Platinum-based Cancer Chemotherapy: An Exploratory Study
Published in Applied immunohistochemistry & molecular morphology (01-06-2022)“…Platinum analogs are commonly used for cancer treatment. There is increasing interest in finding biomarkers which could predict and overcome resistance,…”
Get full text
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