Search Results - "Nadia Abdel-Wahab"

Connective tissue growth factor and regulation of the mesangial cell cycle: Role in cellular hypertrophy by ABDEL WAHAB, Nadia, WESTON, Benjamin S, ROBERTS, Terry, MASON, Roger M

“…Connective tissue growth factor (CTGF) is now considered to be one of the important driver molecules for the pathogenesis of diabetic nephropathy (DN) and…”
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Extracellular matrix metabolism in diabetic nephropathy by MASON, Roger M, NADIA ABDEL WAHAB

“…Diabetic nephropathy is characterized by excessive deposition of extracellular matrix proteins in the mesangium and basement membrane of the glomerulus and in…”
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Connective tissue growth factor CCN2 interacts with and activates the tyrosine kinase receptor TrkA by NADIA ABDEL WAHAB, WESTON, Benjamin S, MASON, Roger M

“…Connective tissue growth factor (CTGF) is implicated as a factor promoting tissue fibrosis in several disorders, including diabetic nephropathy. However, the…”
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CTGF mediates TGF-β-induced fibronectin matrix deposition by upregulating active α5β1 integrin in human mesangial cells by WESTON, Benjamin S, NADIA ABDEL WAHAB, MASON, Roger M

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Modulation of the TGFβ/Smad signaling pathway in mesangial cells by CTGF/CCN2 by Abdel Wahab, Nadia, Weston, Benjamin S., Mason, Roger M.

“…Transforming growth factor-beta (TGFβ) drives fibrosis in diseases such as diabetic nephropathy (DN). Connective tissue growth factor (CTGF; CCN2) has also…”
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Inactivation of Smad-Transforming Growth Factor β Signaling by Ca2+-Calmodulin-Dependent Protein Kinase II by Stephen J. Wicks, Stephen Lui, Nadia Abdel-Wahab, Roger M. Mason, Andrew Chantry

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Thrombospondin-1 is the key activator of TGF-β1 in human mesangial cells exposed to high glucose by YEVDOKIMOVA, Natalia, ABDEL WAHAB, Nadia, MASON, Roger M

“…Elevated levels of transforming growth factor-β1 (TGF-β1) are synthesized by human mesangial cells that are cultured in medium that contains high…”
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Role of connective tissue growth factor in the pathogenesis of diabetic nephropathy by Wahab, N A, Yevdokimova, N, Weston, B S, Roberts, T, Li, X J, Brinkman, H, Mason, R M

“…We characterized a rabbit polyclonal antibody raised against human recombinant connective tissue growth factor (CTGF). The antibody recognised a higher…”
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Connective tissue growth factor and renal diseases: some answers, more questions by Wahab, Nadia Abdel, Mason, Roger M

“…PURPOSE OF REVIEWConnective tissue growth factor (CCN2) has recently received much attention as a possible key determinant of progressive renal fibrosis…”
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Uptake and intracellular transport of the connective tissue growth factor: a potential mode of action by Wahab, N A, Brinkman, H, Mason, R M

“…Connective tissue growth factor (CTGF) is a secreted cysteine-rich protein now considered as an important effector molecule in both physiological and…”
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Modulation of the TGF[beta]/Smad signaling pathway in mesangial cells by CTGF/CCN2 by Nadia Abdel Wahab, Weston, Benjamin S, Mason, Roger M

“…Transforming growth factor-beta (TGFβ) drives fibrosis in diseases such as diabetic nephropathy (DN). Connective tissue growth factor (CTGF; CCN2) has also…”
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Uptake and intracellular transport of the connective tissue growth factor: a potential mode of action by WAHAB, Nadia Abdel, BRINKMAN, Heike, MASON, Roger M.

“…Connective tissue growth factor (CTGF) is a secreted cysteine-rich protein now considered as an important effector molecule in both physiological and…”
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Bacitracin inhibits fibronectin matrix assembly by mesangial cells in high glucose by Weston, Benjamin S., Wahab, Nadia Abdel, Roberts, Terry, Mason, Roger M.

“…Bacitracin inhibits fibronectin matrix assembly by mesangial cells in high glucose. Accumulation of mesangial extracellular matrix is a major characteristic of…”
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The decorin high glucose response element and mechanism of its activation in human mesangial cells by WAHAB, Nadia Abdel, PARKER, Susan, SRAER, Jean-Daniel, MASON, Roger M

“…The decorin gene encodes a proteoglycan with putative structural and regulatory functions whose expression is markedly increased in human mesangial cells (HMC)…”
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Regulation of gene expression by alternative polyadenylation and mRNA instability in hyperglycaemic mesangial cells by Abdel Wahab, N, Gibbs, J, Mason, R M

“…We have used mRNA differential display to identify a novel high-glucose-regulated gene (HGRG-14) in human mesangial cells cultured for up to 21 days in 30 mM…”
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Role of connective tissue growth factor in the pathogenesis of diabetic nephropathy by WAHAB, Nadia Abdel, YEVDOKIMOVA, Natalia, WESTON, Benjamin S., ROBERTS, Terry, LI, Xin Jun, BRINKMAN, Heike, MASON, Roger M.

“…We characterized a rabbit polyclonal antibody raised against human recombinant connective tissue growth factor (CTGF). The antibody recognised a higher…”
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Expression of connective tissue growth factor in human renal fibroblasts : Regulatory roles of RhoA and cAMP by HEUSINGER-RIBEIRO, Juliane, EBERLEIN, Michael, WAHAB, Nadia Abdel, GOPPELT-STRUEBE, Margarete

“…The induction of connective tissue growth factor (CTGF) was investigated in a human renal fibroblast cell line that exhibited many characteristics of primary…”
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Decorin suppresses transforming growth factor-beta-induced expression of plasminogen activator inhibitor-1 in human mesangial cells through a mechanism that involves Ca2+-dependent phosphorylation of Smad2 at serine-240 by Abdel-Wahab, Nadia, Wicks, Stephen J, Mason, Roger M, Chantry, Andrew

“…Transforming growth factor-beta (TGFbeta) is a key mediator of extracellular matrix (ECM) accumulation in sclerotic kidney diseases such as diabetic…”
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Modulation of the TGFbeta/Smad signaling pathway in mesangial cells by CTGF/CCN2 by Wahab, Nadia Abdel, Weston, Benjamin S, Mason, Roger M

“…Transforming growth factor-beta (TGFbeta) drives fibrosis in diseases such as diabetic nephropathy (DN). Connective tissue growth factor (CTGF; CCN2) has also…”
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CTGF mediates TGF-beta-induced fibronectin matrix deposition by upregulating active alpha5beta1 integrin in human mesangial cells by Weston, Benjamin S, Wahab, Nadia Abdel, Mason, Roger M

“…Excessive deposition of fibronectin in the glomerular mesangium in diabetic nephropathy (DN) is partly due to the induction of transforming growth factor-beta…”
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