Search Results - "Nader Bagheri"
-
1
Design of a multi-epitope vaccine against cervical cancer using immunoinformatics approaches
Published in Scientific reports (11-06-2021)“…Cervical cancer, caused by human papillomavirus (HPV), is the fourth most common type of cancer among women worldwide. While HPV prophylactic vaccines are…”
Get full text
Journal Article -
2
Antibody–drug conjugates (ADCs) for cancer therapy: Strategies, challenges, and successes
Published in Journal of cellular physiology (01-05-2019)“…Targeted delivery of therapeutic molecules into cancer cells is considered as a promising strategy to tackle cancer. Antibody–drug conjugates (ADCs), in which…”
Get full text
Journal Article -
3
Potential drugs used in the antibody–drug conjugate (ADC) architecture for cancer therapy
Published in Journal of cellular physiology (01-01-2020)“…Cytotoxic small‐molecule drugs have a major influence on the fate of antibody–drug conjugates (ADCs). An ideal cytotoxic agent should be highly potent, remain…”
Get full text
Journal Article -
4
Designing a novel multi‑epitope vaccine against Ebola virus using reverse vaccinology approach
Published in Scientific reports (11-05-2022)“…Ebola virus (EBOV) is a dangerous zoonotic infectious disease. To date, more than 25 EBOV outbreaks have been documented, the majority of which have occurred…”
Get full text
Journal Article -
5
Chimeric Antigen Receptor Based Therapy as a Potential Approach in Autoimmune Diseases: How Close Are We to the Treatment?
Published in Frontiers in immunology (26-11-2020)“…Despite significant breakthroughs in understanding of immunological and physiological features of autoimmune diseases, there is currently no specific…”
Get full text
Journal Article -
6
In silico design of a multi-epitope vaccine against HPV16/18
Published in BMC bioinformatics (02-08-2022)“…Abstract Background Cervical cancer is the fourth most common cancer affecting women and is caused by human Papillomavirus (HPV) infections that are sexually…”
Get full text
Journal Article -
7
The biological functions of IL-17 in different clinical expressions of Helicobacter pylori-infection
Published in Microbial pathogenesis (01-04-2015)“…Helicobacter pylori (H. pylori) infection is regarded as the major cause of various gastric diseases (gastritis, peptic ulcers and gastric cancer) and induces…”
Get full text
Journal Article -
8
Crosstalk between myeloid‐derived suppressor cells and the immune system in prostate cancer
Published in Journal of leukocyte biology (01-01-2020)“…Prostate cancer is the second most common cancer and the fifth leading cause of cancer‐associated death in men. Previous studies have revealed a surprising…”
Get full text
Journal Article -
9
The protective effects of resveratrol on ulcerative colitis via changing the profile of Nrf2 and IL-1β protein
Published in Molecular biology reports (01-09-2020)“…Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) with increasing incidence and prevalence in developed countries. The presence of inflammatory…”
Get full text
Journal Article -
10
Serum levels of IL-32 in patients with coronary artery disease and its relationship with the serum levels of IL-6 and TNF-α
Published in Molecular biology reports (01-05-2021)“…The coronary artery disease (CAD) is a chronic inflammatory disease caused by atherosclerosis, in which arteries become clogged due to plaque formation, fat…”
Get full text
Journal Article -
11
Role of Th22 cells in Helicobacter pylori-related gastritis and peptic ulcer diseases
Published in Molecular biology reports (01-12-2019)“…Helicobacter pylori ( H. pylori ) has been shown to be one of the leading causes of peptic ulcer diseases (PUDs) and gastritis. T helper-22 (Th22) cells and…”
Get full text
Journal Article -
12
Comparative Immune Response in Children and Adults with H. pylori Infection
Published in Journal of immunology research (01-01-2015)“…Helicobacter pylori (H. pylori) infection is generally acquired during early childhood; therefore, the immune response which usually takes place at this age…”
Get full text
Journal Article -
13
Virulence factors of Helicobacter pylori vacA increase markedly gastric mucosal TGF-β1 mRNA expression in gastritis patients
Published in Microbial pathogenesis (01-02-2014)“…Helicobacter pylori (H. pylori) infection is the main cause of gastric inflammation. Regulatory T cells (Treg cells) suppress the activation and proliferation…”
Get full text
Journal Article -
14
Possible involvement of PI3K/AKT/mTOR signaling pathway in the protective effect of selegiline (deprenyl) against memory impairment following ischemia reperfusion in rat
Published in Neuropeptides (Edinburgh) (01-10-2019)“…Short-term cerebral ischemia led to memory dysfunction. There is a pressing need to introduce effective agents to reduce complications of the ischemia…”
Get full text
Journal Article -
15
Development and biological assessment of MMAE-trastuzumab antibody–drug conjugates (ADCs)
Published in Breast cancer (Tokyo, Japan) (2021)“…Background Trastuzumab, a humanized monoclonal antibody targeting Human Epidermal growth factor Receptor 2 (HER2), is a therapeutic option used for the…”
Get full text
Journal Article -
16
Evaluating the MicroRNA Expression of IL-35 and IL-37 in Helicobacter Pylori-infected Patients with Gastritis and Gastric Ulcer
Published in Iranian journal of allergy, asthma, and immunology (01-02-2022)“…Interleukin (IL)-35 and IL-37 are two anti-inflammatory cytokines. IL-35 inhibits the development of T-effector cells such as Th1, and Th17; while increasing…”
Get full text
Journal Article -
17
Determination of CagA EPIYA motif in Helicobacter pylori strains isolated from patients with digestive disorder
Published in Heliyon (01-09-2020)“…This study was conducted to identify patterns of cagA EPIYA motifs in H. pylori strains isolated from patients with gastrointestinal diseases in Hospitals of…”
Get full text
Journal Article -
18
A Study of Autoantibodies Against some Central Nervous System Antigens and the IL-35 Serum Level in Schizophrenia
Published in Iranian journal of allergy, asthma, and immunology (01-08-2022)“…Schizophrenia (SCZ) is a debilitating mental disorder with various causes involving complex interactions between genetic factors and environmental agents. The…”
Get full text
Journal Article -
19
The expression analysis of Fra-1 gene and IL-11 protein in Iranian patients with ulcerative colitis
Published in BMC immunology (18-06-2018)“…Fra-1 (fosl1) belongs to the activator protein1 (AP-1) family inducing IL-11 expression in oxidative stress condition. IL-11 plays a pivotal role in protecting…”
Get full text
Journal Article -
20
COVID-19 and the potential of Janus family kinase (JAK) pathway inhibition: A novel treatment strategy
Published in Frontiers in medicine (30-08-2022)“…Recent evidence proposed that the severity of the coronavirus disease 2019 (COVID-19) in patients is a consequence of cytokine storm, characterized by…”
Get full text
Journal Article