Search Results - "Nadel, Brian B."
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Amnion responses to intrauterine inflammation and effects of inhibition of TNF signaling in preterm Rhesus macaque
Published in iScience (17-11-2023)“…Intrauterine infection/inflammation (IUI) is a frequent complication of pregnancy leading to preterm labor and fetal inflammation. How inflammation is…”
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Analysis of gene expression from human breastmilk cells: A comparison between low and high producers, and the influence of anxiety and depression on milk production, gene expression and bacterial production
Published in Heliyon (01-11-2021)“…Breastmilk is considered the gold standard of infant nutrition. Many mothers have difficulty with breastfeeding and over 50% of women stop due to perceived low…”
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Systematic evaluation of transcriptomics-based deconvolution methods and references using thousands of clinical samples
Published in Briefings in bioinformatics (05-11-2021)“…Estimating cell type composition of blood and tissue samples is a biological challenge relevant in both laboratory studies and clinical care. In recent years,…”
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The Gene Expression Deconvolution Interactive Tool (GEDIT): accurate cell type quantification from gene expression data
Published in Gigascience (16-02-2021)“…The cell type composition of heterogeneous tissue samples can be a critical variable in both clinical and laboratory settings. However, current experimental…”
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Cell type-specific genetic regulation of gene expression across human tissues
Published in Science (American Association for the Advancement of Science) (11-09-2020)“…The Genotype-Tissue Expression (GTEx) project has identified expression and splicing quantitative trait loci in cis (QTLs) for the majority of genes across a…”
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Genetic Mechanisms of Immune Evasion in Colorectal Cancer
Published in Cancer discovery (01-06-2018)“…To understand the genetic drivers of immune recognition and evasion in colorectal cancer, we analyzed 1,211 colorectal cancer primary tumor samples, including…”
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