Search Results - "Nadeem Akhtar, M."

Flavokawain A induces apoptosis in MCF-7 and MDA-MB231 and inhibits the metastatic process in vitro by Abu, Nadiah, Akhtar, M Nadeem, Yeap, Swee Keong, Lim, Kian Lam, Ho, Wan Yong, Zulfadli, Aimi Jamil, Omar, Abdul Rahman, Sulaiman, Mohd Roslan, Abdullah, Mohd Puad, Alitheen, Noorjahan Banu

“…The kava-kava plant (Piper methsyticum) is traditionally known as the pacific elixir by the pacific islanders for its role in a wide range of biological…”
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3-Bromo-1-hydroxy-9,10-anthraquinone (BHAQ) inhibits growth and migration of the human breast cancer cell lines MCF-7 and MDA-MB231 by Abu, Nadiah, Akhtar, M Nadeem, Ho, Wan Yong, Yeap, Swee Keong, Alitheen, Noorjahan Banu

“…Breast cancer is becoming more prominent in women today. As of now, there are no effective treatments in treating metastatic breast cancer. We have tested the…”
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Combinatorial Cytotoxic Effects of Damnacanthal and Doxorubicin against Human Breast Cancer MCF-7 Cells in Vitro by Aziz, Muhammad Yusran Abdul, Abu, Nadiah, Yeap, Swee Keong, Ho, Wan Yong, Omar, Abdul Rahman, Ismail, Nor Hadiani, Ahmad, Syahida, Pirozyan, Mehdi R, Akhtar, Nadeem M, Alitheen, Noorjahan Banu

“…Despite progressive research being done on drug therapy to treat breast cancer, the number of patients succumbing to the disease is still a major issue…”
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The flavokawains: uprising medicinal chalcones by Abu, Nadiah, Ho, Wan Yong, Yeap, Swee Keong, Akhtar, M Nadeem, Abdullah, Mohd Puad, Omar, Abdul Rahman, Alitheen, Noorjahan Banu

“…Plant-based compounds have been in the spotlight in search of new and promising drugs. Flavokawain A, B and C are naturally occurring chalcones that have been…”
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α-Glucosidase Inhibitory Activity of Triterpenoids from Cichorium intybus by Atta-ur-Rahman, Zareen, Seema, Choudhary, M. Iqbal, Akhtar, M. Nadeem, Khan, Shamsun Nahar

“…Two new triterpenoids, 18α,19β-20(30)-taraxasten-3β,21α-diol (cichoridiol) (1) and 17-epi-methyl-6-hydroxyangolensate (intybusoloid) (2), were obtained from…”
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In Vivo Anti-Tumor Effects of Flavokawain A in 4T1 Breast Cancer Cell-Challenged Mice by Abu, Nadiah, Mohamed, Nurul Elyani, Yeap, Swee Keong, Lim, Kian Lam, Akhtar, M Nadeem, Zulfadli, Aimi Jamil, Kee, Beh Boon, Abdullah, Mohd Puad, Omar, Abdul Rahman, Alitheen, Noorjahan Banu

“…Flavokawain A is a chalcone that can be found in the kava-kava plant (Piper methsyticum) extract. The kava-kava plant has been reported to possess anti-cancer,…”
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In vitro Toxicity and in vivo Immunomodulatory Effects of Flavokawain A and Flavokawain B in Balb/C Mice by Abu, Nadiah, Mohameda, Nurul Elyani, Tangarajoo, Nirosha, Yeap, Swee Keong, Akhtar, M Nadeem, Abdullah, Mohd Puad, Omar, Abdul Rahman, Alitheen, Noorjahan Banu

“…Flavokawains are chalcones that can be found in the root extracts of the kava-kava (Piper methysticum) plant. Flavokawain A and flavokawain B are known to…”
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Flavokawain derivative FLS induced G2/M arrest and apoptosis on breast cancer MCF-7 cell line by Ali, Norlaily Mohd, Akhtar, M Nadeem, Ky, Huynh, Lim, Kian Lam, Abu, Nadiah, Zareen, Seema, Ho, Wan Yong, Alan-Ong, Han Kiat, Tan, Sheau Wei, Alitheen, Noorjahan Banu, Ismail, Jamil Bin, Yeap, Swee Keong, Kamarul, Tunku

“…Known as naturally occurring biologically active compounds, flavokawain A and B are the leading chalcones that possess anticancer properties. Another…”
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A triterpenoidal saponin and sphingolipids from Pteleopsis hylodendron by Atta-ur-Rahman, Zareen, Seema, Choudhary, M. Iqbal, Akhtar, M. Nadeem, Ngounou, F.N.

“…A triterpenoidal saponin bellericagenin {B 3- O-[β- d-glucopyranosyl-(1 → 2)-α- d-glucopyranoside] ( 1) (Pteleopsoside)}, and two sphingolipids,…”
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Cardamonin from Alpinia rafflesiana inhibits inflammatory responses in IFN-γ/LPS-stimulated BV2 microglia via NF-κB signalling pathway by Chow, Yuh-Lit, Lee, Ka-Heng, Vidyadaran, Sharmili, Lajis, Nordin Haji, Akhtar, M. Nadeem, Israf, Daud Ahmad, Syahida, Ahmad

“…The increasing prevalence of neurodegenerative diseases has prompted investigation into innovative therapeutics over the last two decades. Non-steroidal…”
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Synthetic curcumin derivative DK1 possessed G2/M arrest and induced apoptosis through accumulation of intracellular ROS in MCF-7 breast cancer cells by Ali, Norlaily Mohd, Yeap, Swee Keong, Abu, Nadiah, Lim, Kian Lam, Ky, Huynh, Pauzi, Ahmad Zaim Mat, Ho, Wan Yong, Tan, Sheau Wei, Alan-Ong, Han Kiat, Zareen, Seema, Alitheen, Noorjahan Banu, Akhtar, M Nadeem

“…Curcumin is a lead compound of the rhizomes of and possess a broad range of pharmacological activities. Chemically, curcumin is 1,3-dicarbonyl class of…”
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Synthesis, antimicrobial evaluation and hemolytic activity of 2-[[5-alkyl/aralkyl substituted-1,3,4-oxadiazol-2-yl]thio]-N-[4-(4-morpholinyl)phenyl]acetamide derivatives by Gul, Samreen, Aziz-ur-Rehman, Abbasi, M. Athar, Khan, Khalid Mohammed, Nafeesa, Khadija, Siddiqa, Asia, Akhtar, M. Nadeem, Shahid, Muhammad, Subhani, Zinayyera

“…2,5-Disubstituted 1,3,4-oxadiazole compounds are one of the most attractive classes for researchers due to their pharmacological activities. In the current…”
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New class of steroidal alkaloids from Fritillaria imperialis by Akhtar, M.Nadeem, Atta-ur-Rahman, Choudhary, M.Iqbal, Sener, Bilge, Erdogan, Ilkay, Tsuda, Yoshisuke

“…Two members of a new class of C-nor- d-homo steroidal alkaloids, impranine ( 1) and dihydroimpranine ( 2) along with a new pyridyl-pregnane-type steroidal…”
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The in vivo anti-tumor effect of curcumin derivative (2E,6E)-2,6-bis(4-hydroxy-3-methoxybenzylidene)cyclohexanone (BHMC) on 4T1 breast cancer cells by Razak, Nursyamirah Abd, Akhtar, M. Nadeem, Abu, Nadiah, Ho, Wan Yong, Tan, Sheau Wei, Zareen, Seema, Taj-ud-din, Saiful Nizam bin, Long, Kamariah, Alitheen, Noorjahan Banu, Yeap, Swee Keong

“…Curcumin is one of the promising natural products extracted from the rhizomes of curcuma longa and has been extensively investigated by researchers to explore…”
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Revision of the Absolute Configuration of Plumericin and Isoplumericin from Plumeria rubra by Elsässer, Brigitta, Krohn, Karsten, Nadeem Akhtar, M., Flörke, Ulrich, Kouam, Simeon F., Kuigoua, Merlin Guy, Ngadjui, Bonaventure T., Abegaz, Berhanu M., Antus, Sándor, Kurtán, Tibor

“…The absolute configurations of plumericin (1) and isoplumericin (2), isolated from Plumeria rubra, were re‐assigned based on a combination of X‐ray…”
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In vivo antitumor and antimetastatic effects of flavokawain B in 4T1 breast cancer cell-challenged mice by Abu, Nadiah, Mohamed, Nurul Elyani, Yeap, Swee Keong, Lim, Kian Lam, Akhtar, M Nadeem, Zulfadli, Aimi Jamil, Kee, Beh Boon, Abdullah, Mohd Puad, Omar, Abdul Rahman, Alitheen, Noorjahan Banu

“…Flavokawain B (FKB) is a naturally occurring chalcone that can be isolated through the root extracts of the kava-kava plant (Piper methysticum). It can also be…”
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Dual Regulation of Cell Death and Cell Survival upon Induction of Cellular Stress by Isopimara-7,15-Dien-19-Oic Acid in Cervical Cancer, HeLa Cells In vitro by Abu, Nadiah, Yeap, Swee K, Pauzi, Ahmad Z Mat, Akhtar, M Nadeem, Zamberi, Nur R, Ismail, Jamil, Zareen, Seema, Alitheen, Noorjahan B

“…The Fritillaria imperialis is an ornamental flower that can be found in various parts of the world including Iraq, Afghanistan, Pakistan, and the Himalayas…”
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Flavokawain B induced cytotoxicity in two breast cancer cell lines, MCF-7 and MDA-MB231 and inhibited the metastatic potential of MDA-MB231 via the regulation of several tyrosine kinases In vitro by Abu, Nadiah, Akhtar, M Nadeem, Yeap, Swee Keong, Lim, Kian Lam, Ho, Wan Yong, Abdullah, Mohd Puad, Ho, Chai Ling, Omar, Abdul Rahman, Ismail, Jamil, Alitheen, Noorjahan Banu

“…The kava-kava plant (Piper methysticum) is traditionally consumed by the pacific islanders and has been linked to be involved in several biological activities…”
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Revision of the Absolute Configuration of Plumericin and Isoplumericin fromPlumeria rubra by Elsässer, Brigitta, Krohn, Karsten, Nadeem Akhtar, M., Flörke, Ulrich, Kouam, Simeon F., Kuigoua, Merlin Guy, Ngadjui, Bonaventure T., Abegaz, Berhanu M., Antus, Sándor, Kurtán, Tibor

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Synthesis of an anthraquinone derivative (DHAQC) and its effect on induction of G2/M arrest and apoptosis in breast cancer MCF-7 cell line by Yeap, SweeKeong, Akhtar, Muhammad Nadeem, Lim, Kian Lam, Abu, Nadiah, Ho, Wan Yong, Zareen, Seema, Roohani, Kiarash, Ky, Huynh, Tan, Sheau Wei, Lajis, Nordin, Alitheen, Noorjahan Banu

“…Anthraquinones are an important class of naturally occurring biologically active compounds. In this study, anthraquinone derivative…”
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