Search Results - "Nadal, Eulàlia"

The HOG pathway and the regulation of osmoadaptive responses in yeast by de Nadal, Eulàlia, Posas, Francesc

“…Abstract Cells coordinate intracellular activities in response to changes in the extracellular environment to maximize their probability of survival and…”
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The p38 Pathway: From Biology to Cancer Therapy by Martínez-Limón, Adrián, Joaquin, Manel, Caballero, María, Posas, Francesc, de Nadal, Eulàlia

“…The p38 MAPK pathway is well known for its role in transducing stress signals from the environment. Many key players and regulatory mechanisms of this…”
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Controlling gene expression in response to stress by de Nadal, Eulàlia, Ammerer, Gustav, Posas, Francesc

“…Key Points Exposure of cells to suboptimal growth conditions or to any environment that reduces cell viability or fitness can be considered a stress. Adaptive…”
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Osmostress‐induced gene expression – a model to understand how stress‐activated protein kinases (SAPKs) regulate transcription by Nadal, Eulàlia, Posas, Francesc

“…Adaptation is essential for maximizing cell survival and for cell fitness in response to sudden changes in the environment. Several aspects of cell physiology…”
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Distributed biological computation with multicellular engineered networks by Regot, Sergi, Macia, Javier, Conde, Núria, Furukawa, Kentaro, Kjellén, Jimmy, Peeters, Tom, Hohmann, Stefan, de Nadal, Eulàlia, Posas, Francesc, Solé, Ricard

“…Circuit training for bioengineers For the creativity of synthetic biologists to be unleashed, basic circuits must become truly interchangeable — that is,…”
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Control of Cdc28 CDK1 by a Stress-Induced lncRNA by Nadal-Ribelles, Mariona, Solé, Carme, Xu, Zhenyu, Steinmetz, Lars M., de Nadal, Eulàlia, Posas, Francesc

“…Genomic analysis has revealed the existence of a large number of long noncoding RNAs (lncRNAs) with different functions in a variety of organisms, including…”
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Multilayered control of gene expression by stress-activated protein kinases by de Nadal, Eulàlia, Posas, Francesc

“…Stress‐activated protein kinases (SAPKs) are key elements for intracellular signalling networks that serve to respond and adapt to extracellular changes…”
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Implementation of Complex Biological Logic Circuits Using Spatially Distributed Multicellular Consortia by Macia, Javier, Manzoni, Romilde, Conde, Núria, Urrios, Arturo, de Nadal, Eulàlia, Solé, Ricard, Posas, Francesc

“…Engineered synthetic biological devices have been designed to perform a variety of functions from sensing molecules and bioremediation to energy production and…”
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LRRC8A-containing chloride channel is crucial for cell volume recovery and survival under hypertonic conditions by Serra, Selma A., Stojakovic, Predrag, Amat, Ramon, Rubio-Moscardo, Fanny, Latorre, Pablo, Seisenbacher, Gerhard, Canadell, David, Böttcher, René, Aregger, Michael, Moffat, Jason, de Nadal, Eulàlia, Valverde, Miguel A., Posas, Francesc

“…Regulation of cell volume is essential for tissue homeostasis and cell viability. In response to hypertonic stress, cells need rapid electrolyte influx to…”
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Rapid reversible changes in compartments and local chromatin organization revealed by hyperosmotic shock by Amat, Ramon, Böttcher, René, Le Dily, François, Vidal, Enrique, Quilez, Javier, Cuartero, Yasmina, Beato, Miguel, de Nadal, Eulàlia, Posas, Francesc

“…Nuclear architecture is decisive for the assembly of transcriptional responses. However, how chromosome organization is dynamically modulated to permit rapid…”
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The regulation of Net1/Cdc14 by the Hog1 MAPK upon osmostress unravels a new mechanism regulating mitosis by Jiménez, Javier, Queralt, Ethel, Posas, Francesc, de Nadal, Eulàlia

“…During evolution, cells have developed a plethora of mechanisms to optimize survival in a changing and unpredictable environment. In this regard, they have…”
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Hog1 Targets Whi5 and Msa1 Transcription Factors To Downregulate Cyclin Expression upon Stress by González-Novo, Alberto, Jiménez, Javier, Clotet, Josep, Nadal-Ribelles, Mariona, Cavero, Santiago, de Nadal, Eulàlia, Posas, Francesc

“…Yeast cells have developed complex mechanisms to cope with extracellular insults. An increase in external osmolarity leads to activation of the…”
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Evolution of protein phosphorylation across 18 fungal species by Studer, Romain A., Rodriguez-Mias, Ricard A., Haas, Kelsey M., Hsu, Joanne I., Viéitez, Cristina, Solé, Carme, Swaney, Danielle L., Stanford, Lindsay B., Liachko, Ivan, Böttcher, René, Dunham, Maitreya J., de Nadal, Eulàlia, Posas, Francesc, Beltrao, Pedro, Villén, Judit

“…Living organisms have evolved protein phosphorylation, a rapid and versatile mechanism that drives signaling and regulates protein function. We report the…”
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Multiple signaling kinases target Mrc1 to prevent genomic instability triggered by transcription-replication conflicts by Duch, Alba, Canal, Berta, Barroso, Sonia I., García-Rubio, María, Seisenbacher, Gerhard, Aguilera, Andrés, de Nadal, Eulàlia, Posas, Francesc

“…Conflicts between replication and transcription machineries represent a major source of genomic instability and cells have evolved strategies to prevent such…”
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The p38 and Hog1 SAPKs control cell cycle progression in response to environmental stresses by Duch, Alba, de Nadal, Eulàlia, Posas, Francesc

“…In response to environmental stresses, cells need to activate an adaptive program to maximize cell progression and survival. Stress-activated protein kinases…”
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A genetic analysis reveals novel histone residues required for transcriptional reprogramming upon stress by Viéitez, Cristina, Martínez-Cebrián, Gerard, Solé, Carme, Böttcher, René, Potel, Clement M, Savitski, Mikhail M, Onnebo, Sara, Fabregat, Marc, Shilatifard, Ali, Posas, Francesc, de Nadal, Eulàlia

“…Abstract Cells have the ability to sense, respond and adapt to environmental fluctuations. Stress causes a massive reorganization of the transcriptional…”
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Timing of gene expression in a cell‐fate decision system by Aymoz, Delphine, Solé, Carme, Pierre, Jean‐Jerrold, Schmitt, Marta, de Nadal, Eulàlia, Posas, Francesc, Pelet, Serge

“…During development, morphogens provide extracellular cues allowing cells to select a specific fate by inducing complex transcriptional programs. The mating…”
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Understanding Retinoblastoma Post-Translational Regulation for the Design of Targeted Cancer Therapies by Janostiak, Radoslav, Torres-Sanchez, Ariadna, Posas, Francesc, de Nadal, Eulàlia

“…The retinoblastoma protein (Rb1) is a prototypical tumor suppressor protein whose role was described more than 40 years ago. Together with p107 (also known as…”
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Transient Activation of the HOG MAPK Pathway Regulates Bimodal Gene Expression by Pelet, Serge, Rudolf, Fabian, Nadal-Ribelles, Mariona, de Nadal, Eulàlia, Posas, Francesc, Peter, Matthias

“…Mitogen-activated protein kinase (MAPK) cascades are conserved signaling modules that control many cellular processes by integrating intra- and extracellular…”
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Positive feedback induces switch between distributive and processive phosphorylation of Hog1 by Mosbacher, Maximilian, Lee, Sung Sik, Yaakov, Gilad, Nadal-Ribelles, Mariona, de Nadal, Eulàlia, van Drogen, Frank, Posas, Francesc, Peter, Matthias, Claassen, Manfred

“…Cellular decision making often builds on ultrasensitive MAPK pathways. The phosphorylation mechanism of MAP kinase has so far been described as either…”
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