Search Results - "Nacken, Peter J"

Therapeutic Intervention in Multiple Sclerosis with Alpha B-Crystallin: A Randomized Controlled Phase IIa Trial by van Noort, Johannes M, Bsibsi, Malika, Nacken, Peter J, Verbeek, Richard, Venneker, Edna H G

“…As a molecular chaperone and activator of Toll-like receptor 2-mediated protective responses by microglia and macrophages, the small heat shock protein alpha…”
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Demyelination during multiple sclerosis is associated with combined activation of microglia/macrophages by IFN-γ and alpha B-crystallin by Bsibsi, Malika, Peferoen, Laura A. N., Holtman, Inge R., Nacken, Peter J., Gerritsen, Wouter H., Witte, Maarten E., van Horssen, Jack, Eggen, Bart J. L., van der Valk, Paul, Amor, Sandra, van Noort, Johannes M.

“…Activated microglia and macrophages play a key role in driving demyelination during multiple sclerosis (MS), but the factors responsible for their activation…”
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Activation of an immune-regulatory macrophage response and inhibition of lung inflammation in a mouse model of COPD using heat-shock protein alpha B-crystallin-loaded PLGA microparticles by van Noort, Johannes M, Bsibsi, Malika, Nacken, Peter J, Gerritsen, Wouter H, Amor, Sandra, Holtman, Inge R, Boddeke, Erik, van Ark, Ingrid, Leusink-Muis, Thea, Folkerts, Gert, Hennink, Wim E, Amidi, Maryam

“…Abstract As an extracellular protein, the small heat-shock protein alpha B-crystallin (HSPB5) has anti-inflammatory effects in several mouse models of…”
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Demyelination during multiple sclerosis is associated with combined activation of microglia/macrophages by IFN-[gamma] and alpha B-crystallin by Bsibsi, Malika, Peferoen, Laura A; N, Holtman, Inge R, Nacken, Peter J, Gerritsen, Wouter H, Witte, Maarten E, van Horssen, Jack, Eggen, Bart J; L, van der Valk, Paul, Amor, Sandra, van Noort, Johannes M

“…Activated microglia and macrophages play a key role in driving demyelination during multiple sclerosis (MS), but the factors responsible for their activation…”
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