Search Results - "Nachman, Patrick"

ANCA Glomerulonephritis and Vasculitis by Jennette, J Charles, Nachman, Patrick H

“…ANCA vasculitis has an associated autoimmune response that produces ANCAs that induce distinct pathologic lesions. Pauci-immune necrotizing and crescentic GN…”
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Two for one? CAR-T therapy for lymphoma benefits concurrent autoimmune disorders by Bachanova, Veronika, Nachman, Patrick H.

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Repeat kidney biopsy for lupus nephritis: an important step forward by Nachman, Patrick H

“…There is scant controlled data to guide the use of repeat kidney biopsies to guide therapy in glomerular disease. De Rosa et al. assessed the value of a repeat…”
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What Is the Best Maintenance Therapy for ANCA Vasculitis? by Woerner, Katti, Nachman, Patrick H

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Complete and Partial Remission as Surrogate End Points in Membranous Nephropathy by Thompson, Aliza, Cattran, Daniel C, Blank, Melanie, Nachman, Patrick H

“…Absent a remission of proteinuria, primary membranous nephropathy (MN) can lead to ESRD over many years. Therefore, use of an earlier end point could…”
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Sparsentan and the Expanding Landscape of IgA Nephropathy Treatment by Derebail, Vimal K, Nachman, Patrick H

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Classification of antineutrophil cytoplasmic autoantibody vasculitides: The role of antineutrophil cytoplasmic autoantibody specificity for myeloperoxidase or proteinase 3 in disease recognition and prognosis by Lionaki, Sophia, Blyth, Elizabeth R., Hogan, Susan L., Hu, Yichun, Senior, Brent A., Jennette, Caroline E., Nachman, Patrick H., Jennette, J. Charles, Falk, Ronald J.

“…Objective To compare the usefulness of 3 currently used classification systems in predicting the outcomes of treatment resistance, disease relapse, end‐stage…”
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Advances in ANCA-associated vasculitis and lupus nephritis by Ayoub, Isabelle, Nachman, Patrick H.

“…In 2020 a number of clinical trials have provided insights into therapeutic approaches for the treatment of anti-neutrophil cytoplasmic autoantibody…”
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S3322 Kidney Biopsy Indications and Findings in U.S. Veterans With Inflammatory Bowel Disease by Bren, Alyssa, Reule, Scott, Ravipati, Prasanth, Nachman, Patrick H.

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Proteinuria Reduction as a Surrogate End Point in Trials of IgA Nephropathy by Thompson, Aliza, Carroll, Kevin, A Inker, Lesley, Floege, Jürgen, Perkovic, Vlado, Boyer-Suavet, Sonia, W Major, Rupert, I Schimpf, Judith, Barratt, Jonathan, Cattran, Daniel C, S Gillespie, Barbara, Kausz, Annamaria, W Mercer, Alex, Reich, Heather N, H Rovin, Brad, West, Melissa, Nachman, Patrick H

“…IgA nephropathy (IgAN) is an important cause of ESKD for which there are no approved therapies. A challenge for evaluating treatments for IgAN is the usual…”
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Neutralizing Anti-Rituximab Antibodies and Relapse in Membranous Nephropathy Treated With Rituximab by Boyer-Suavet, Sonia, Andreani, Marine, Lateb, Maël, Savenkoff, Benjamin, Brglez, Vesna, Benzaken, Sylvia, Bernard, Ghislaine, Nachman, Patrick H, Esnault, Vincent, Seitz-Polski, Barbara

“…Membranous Nephropathy (MN) is an autoimmune disease associated with antibodies against podocyte proteins: M-type phospholipase A2 receptor (PLA2R1) or…”
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Disease-specific risk of venous thromboembolic events is increased in idiopathic glomerulonephritis by Barbour, Sean J, Greenwald, Allen, Djurdjev, Ognjenka, Levin, Adeera, Hladunewich, Michelle A, Nachman, Patrick H, Hogan, Susan L, Cattran, Daniel C, Reich, Heather N

“…The risk of venous thromboembolic events is thought to be highest in patients with membranous nephropathy. This association has been recently questioned, and…”
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Interstital lung disease in ANCA vasculitis by Alba, Marco A, Flores-Suárez, Luis Felipe, Henderson, Ashley G, Xiao, Hong, Hu, Peiqi, Nachman, Patrick H, Falk, Ronald J, Charles Jennette, J

“…Abstract Anti-neutrophil cytoplasmic antibodies (ANCA) vasculitides are immune-mediated disorders that primarily affect small blood vessels of the airway and…”
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Epitope specificity determines pathogenicity and detectability in ANCA-associated vasculitis by Roth, Aleeza J, Ooi, Joshua D, Hess, Jacob J, van Timmeren, Mirjan M, Berg, Elisabeth A, Poulton, Caroline E, McGregor, JulieAnne, Burkart, Madelyn, Hogan, Susan L, Hu, Yichun, Winnik, Witold, Nachman, Patrick H, Stegeman, Coen A, Niles, John, Heeringa, Peter, Kitching, A Richard, Holdsworth, Stephen, Jennette, J Charles, Preston, Gloria A, Falk, Ronald J

“…Anti-neutrophil cytoplasmic antibody-associated (ANCA-associated) small vessel necrotizing vasculitis is caused by immune-mediated inflammation of the vessel…”
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Living Donor Kidney Transplant in Recipients With Glomerulonephritis: Donor Recipient Biologic Relationship and Allograft Outcomes by El-Rifai, Rasha, Bregman, Adam, Klomjit, Nattawat, Spong, Richard, Jackson, Scott, Nachman, Patrick H, Riad, Samy

“…Using the Scientific Registry of Transplant Recipients, we examined the association between donor-recipient biologic relationship and long-term recipient and…”
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Immunoglobulins G from patients with ANCA-associated vasculitis are atypically glycosylated in both the Fc and Fab regions and the relation to disease activity by Lardinois, Olivier M, Deterding, Leesa J, Hess, Jacob J, Poulton, Caroline J, Henderson, Candace D, Jennette, J Charles, Nachman, Patrick H, Falk, Ronald J

“…Anti-neutrophil cytoplasmic autoantibodies (ANCA) directed against myeloperoxidase (MPO) and proteinase 3 (PR3) are pathogenic in ANCA-associated vasculitis…”
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An Outcomes-Based Definition of Proteinuria Remission in Focal Segmental Glomerulosclerosis by Troost, Jonathan P, Trachtman, Howard, Nachman, Patrick H, Kretzler, Matthias, Spino, Cathie, Komers, Radko, Tuller, Sarah, Perumal, Kalyani, Massengill, Susan F, Kamil, Elaine S, Oh, Gia, Selewski, David T, Gipson, Patrick, Gipson, Debbie S

“…Proteinuria is used as an indicator of FSGS disease activity, but its use as a clinical trial end point is not universally accepted. The goal of this study was…”
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Predictors of treatment outcomes in ANCA-associated vasculitis with severe kidney failure by Lee, Taewoo, Gasim, Adil, Derebail, Vimal K, Chung, Yunro, McGregor, JulieAnne G, Lionaki, Sophia, Poulton, Caroline J, Hogan, Susan L, Jennette, J Charles, Falk, Ronald J, Nachman, Patrick H

“…In ANCA-associated GN, severe renal dysfunction portends a poor prognosis for renal recovery and patient survival. This study evaluated the prognostic factors…”
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Predictors of relapse and treatment resistance in antineutrophil cytoplasmic antibody-associated small-vessel vasculitis by HOGAN, Susan L, FALK, Ronald J, CHIN, Hyunsook, JIANWEN CAI, JENNETTE, Caroline E, JENNETTE, J. Charles, NACHMAN, Patrick H

“…Predictors of treatment resistance and relapse have not been well described in antineutrophil cytoplasmic antibody (ANCA)-associated small-vessel vasculitis…”
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Venous Thromboembolism in Patients with Membranous Nephropathy by Lionaki, Sophia, Derebail, Vimal K, Hogan, Susan L, Barbour, Sean, Lee, Taewoo, Hladunewich, Michelle, Greenwald, Allen, Hu, Yichun, Jennette, Caroline E, Jennette, J Charles, Falk, Ronald J, Cattran, Daniel C, Nachman, Patrick H, Reich, Heather N

“…The aims of this study were to determine the frequency of venous thromboembolic events in a large cohort of patients with idiopathic membranous nephropathy and…”
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