Search Results - "Naccarato, Antonio Giuseppe"
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Laser Capture Microdissection and RNA-Seq Analysis: High Sensitivity Approaches to Explain Histopathological Heterogeneity in Human Glioblastoma FFPE Archived Tissues
Published in Frontiers in oncology (07-06-2019)“…Laser capture microdissection (LCM) coupled with RNA-seq is a powerful tool to identify genes that are differentially expressed in specific histological tumor…”
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Metronomic Ceramide Analogs Inhibit Angiogenesis in Pancreatic Cancer through Up-regulation of Caveolin-1 and Thrombospondin-1 and Down-regulation of Cyclin D1
Published in Neoplasia (New York, N.Y.) (01-09-2012)“…Abstract AIMS: To evaluate the antitumor and antiangiogenic activity of metronomic ceramide analogs and their relevant molecular mechanisms. METHODS: Human…”
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Lymphoepitelioma-like hepatocellular carcinoma: A case report and a review of the literature
Published in World journal of gastroenterology : WJG (07-08-2008)“…Lymphoepitelioma is a particular form of undifferentiat-ed carcinoma, characterized by a prominent lymphoid stroma, originally described in the nasopharynx…”
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Recent Advances in Cancer Plasticity: Cellular Mechanisms, Surveillance Strategies, and Therapeutic Optimization
Published in Frontiers in oncology (22-04-2020)“…The processes of recurrence and metastasis, through which cancer relapses locally or spreads to distant sites in the body, accounts for more than 90% of…”
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Angioleiomyoma of the knee: An uncommon cause of leg pain. A systematic review of the literature
Published in Interdisciplinary neurosurgery : Advanced techniques and case management (01-12-2020)“…•Angioleiomyoma is a rare benign painful soft tissue tumor, whose subcutaneous location at the knee joint is rare.•The initial presenting symptom for…”
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Editorial: Metabolic reprogramming in breast cancer
Published in Frontiers in oncology (10-11-2022)Get full text
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Gastric cancer prevention targeted on risk assessment: Gastritis OLGA staging
Published in Helicobacter (Cambridge, Mass.) (01-04-2019)“…Gastric cancer (GC) ranks among the most lethal epithelial malignancies, and its striking mortality rate prompts a global prevention strategy. Helicobacter…”
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Doxycycline, an Inhibitor of Mitochondrial Biogenesis, Effectively Reduces Cancer Stem Cells (CSCs) in Early Breast Cancer Patients: A Clinical Pilot Study
Published in Frontiers in oncology (12-10-2018)“…Cancer stem cells (CSCs) have been implicated in tumor initiation, recurrence, metastatic spread and poor survival in multiple tumor types, breast cancers…”
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IDH1 mutation is detectable in plasma cell-free DNA and is associated with survival outcome in glioma patients
Published in BMC cancer (03-01-2024)“…Circulating cell-free DNA (cfDNA, liquid biopsy) is a powerful tool to detect molecular alterations. However, depending on tumor characteristics, biology and…”
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Endothelial Progenitor Cells: An Appraisal of Relevant Data from Bench to Bedside
Published in International journal of molecular sciences (28-11-2021)“…The mobilization of endothelial progenitor cells (EPCs) into circulation from bone marrow is well known to be present in several clinical settings, including…”
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Molecular characterization of low grade and high grade bladder cancer
Published in PloS one (16-01-2019)“…Bladder cancer (BC) is the 9th most common cancer diagnosis worldwide. Low grade (LG) represents 70% of all BCs, characterized by recurrence and rare ability…”
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Mitochondrial mass, a new metabolic biomarker for stem-like cancer cells: Understanding WNT/FGF-driven anabolic signaling
Published in Oncotarget (13-10-2015)“…Here, we developed an isogenic cell model of "stemness" to facilitate protein biomarker discovery in breast cancer. For this purpose, we used knowledge gained…”
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New insights in the expression of stromal caveolin 1 in breast cancer spread to axillary lymph nodes
Published in Scientific reports (02-02-2021)“…Recent evidence suggests that a loss of expression of caveolin in the stromal compartment (sCav-1) of human invasive breast carcinoma (IBC) may be a predictor…”
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Metabolic-imaging of human glioblastoma live tumors: A new precision-medicine approach to predict tumor treatment response early
Published in Frontiers in oncology (05-09-2022)“…Background Glioblastoma (GB) is the most severe form of brain cancer, with a 12-15 month median survival. Surgical resection, temozolomide (TMZ) treatment, and…”
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Loss of c-KIT expression in thyroid cancer cells
Published in PloS one (16-03-2017)“…Papillary thyroid carcinoma is the most frequent histologic type of thyroid tumor. Few studies investigated the role of c-KIT expression in thyroid tumors,…”
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A Mouse Mammary Tumor Virus env -Like Exogenous Sequence Is Strictly Related to Progression of Human Sporadic Breast Carcinoma
Published in The American journal of pathology (01-10-2011)“…A viral etiology of human breast cancer (HBC) has been postulated for decades since the identification of mouse mammary tumor virus (MMTV). The detection of…”
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Region-dependent effects of flibanserin and buspirone on adenylyl cyclase activity in the human brain
Published in The international journal of neuropsychopharmacology (01-06-2002)“…The mode of action of antidepressant drugs may be related to mechanisms of receptor adaptation, involving overall the serotonin 1A (5-HT1A) receptor subtype…”
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Functional Interaction Between BRCA1 and DNA Repair in Yeast May Uncover a Role of RAD50, RAD51, MRE11A , and MSH6 Somatic Variants in Cancer Development
Published in Frontiers in genetics (19-09-2018)“…In this study, we determined if BRCA1 partners involved in DNA double-strand break (DSB) and mismatch repair (MMR) may contribute to breast and ovarian cancer…”
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Dabrafenib and Trametinib prolong coagulation through the inhibition of tissue factor in BRAFv600e mutated melanoma cells in vitro
Published in Cancer cell international (28-08-2019)“…Background Neoplastic cells promote a hypercoagulable state by the expression of cell surface proteins, such as tissue factor. In BRAFv600 mutated melanoma…”
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Sparc-Like Protein 1 Is a New Marker of Human Glioma Progression
Published in Journal of proteome research (05-10-2012)“…High-grade gliomas (glioblastomas) are the most common and deadly brain tumors in adults, currently with no satisfactory treatment available. Apart from de…”
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