Search Results - "Nabors, L B"

Adoptive cell therapy for high grade gliomas using simultaneous temozolomide and intracranial mgmt-modified γδ t cells following standard post-resection chemotherapy and radiotherapy: current strategy and future directions by Nabors, L B, Lamb, L S, Goswami, T, Rochlin, K, Youngblood, S L

“…Cellular therapies, including chimeric antigen receptor T cell therapies (CAR-T), while generally successful in hematologic malignancies, face substantial…”
Get full text

Isolated Central Nervous System Posttransplant Lymphoproliferative Disorder Treated with High‐Dose Intravenous Methotrexate by Nabors, L. B., Palmer, C. A., Julian, B. A., Przekwas, A. M., Kew, C. E.

“…Posttransplant lymphoproliferative disorder (PTLD) is an uncommon neoplastic complication of kidney transplantation, affecting about 1% of recipients. It is…”
Get full text

Cancer susceptibility variants and the risk of adult glioma in a US case–control study by Egan, Kathleen M., Thompson, Reid C., Nabors, L. B., Olson, Jeffrey J., Brat, Daniel J., LaRocca, Renato V., Brem, Steven, Moots, Paul L., Madden, Melissa H., Browning, James E., Ann Chen, Y.

“…Malignant gliomas are the most common and deadly brain tumors. Although their etiology remains elusive, recent studies have narrowed the search for genetic…”
Get full text

PB2136: PLANNED‐USE GLUCARPIDASE FOR OUTPATIENT HIGH DOSE METHOTREXATE (HD‐MTX) ADMINISTRATION IN PATIENTS WITH CNS LYMPHOMA (CNSL) DURING THE COVID‐19 PANDEMIC by Schaff, L., Lobbous, M., Carlow, D., DeAngelis, L., Nabors, L. B., Grommes, C.

Get full text

Amyotrophic Lateral Sclerosis-linked Mutant SOD1 Sequesters Hu Antigen R (HuR) and TIA-1-related Protein (TIAR): IMPLICATIONS FOR IMPAIRED POST-TRANSCRIPTIONAL REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR by Lu, Liang, Wang, Shuying, Zheng, Lei, Li, Xuelin, Suswam, Esther A, Zhang, Xiaowen, Wheeler, Crystal G, Nabors, L.B, Filippova, Natalia, King, Peter H

“…Down-regulation of vascular endothelial growth factor (VEGF) in the mouse leads to progressive and selective degeneration of motor neurons similar to…”
Get full text

Distress and quality of life in primary high-grade brain tumor patients by Kvale, Elizabeth A., Murthy, Rashmi, Taylor, Richard, Lee, Jeannette Y., Nabors, L. B.

“…Goals of work We report on the routine use of the NCCN Distress Thermometer and the Functional Assessment of Cancer Therapy—Brain (FACT-Br) to assess patient…”
Get full text

Hu Antigen Specificities of ANNA-I Autoantibodies in Paraneoplastic Neurological Disease by King, P.H, Redden, D, Palmgren, J.S, Nabors, L.B, Lennon, V.A

“…Despite a broad clinical spectrum, paraneoplastic enecephalomyelitis/sensory neuronopathy (PEM/SSN) is characterized by the presence of a common autoantibody,…”
Get full text

Results of phase II trial of SL-701, a novel immunotherapy targeting IL-13Ra2, EphA2, and survivin, in adults with second-line recurrent glioblastoma (GBM) by Peereboom, D., Nabors, L.B., Kumthekar, P., Badruddoja, M., Fink, K., Lieberman, F., Phuphanich, S., Dunbar, E., Walbert, T., Schiff, D., Tran, D.D., Ashby, L.S., Butowski, N., Iwamoto, F., Lindsay, R., Bullington, J., Schulder, M., Sherman, J., Brooks, C., Reardon, D.

Get full text

Altered expression of the mRNA stability factor HuR promotes cyclooxygenase-2 expression in colon cancer cells by Dixon, D A, Tolley, N D, King, P H, Nabors, L B, McIntyre, T M, Zimmerman, G A, Prescott, S M

“…Cyclooxygenase-2 (COX-2) expression is normally tightly regulated. However, constitutive overexpression plays a key role in colon carcinogenesis. To understand…”
Get full text

Phase I trial of sorafenib in patients with recurrent or progressive malignant glioma by Nabors, L. B., Supko, J. G., Rosenfeld, M., Chamberlain, M., Phuphanich, S., Batchelor, T., Desideri, S., Ye, X., Wright, J., Gujar, S., Grossman, S. A.

“…Sorafenib is an inhibitor of multiple kinases that has demonstrated antiproliferative and antiangiogenic activity in a number of in vitro and in vivo model…”
Get full text

High-resolution longitudinal assessment of flow and permeability in mouse glioma vasculature: Sequential small molecule and SPIO dynamic contrast agent MRI by Pike, M.M., Stoops, C.N., Langford, C.P., Akella, N.S., Nabors, L.B., Gillespie, G.Y.

“…The poor prognosis associated with malignant glioma is largely attributable to its invasiveness and robust angiogenesis. Angiogenesis involves host–tumor…”
Get full text

Human cytomegalovirus infection and expression in human malignant glioma by COBBS, Charles S, HARKINS, Lualhati, SAMANTA, Minu, GILLESPIE, G. Yancey, BHARARA, Suman, KING, Peter H, NABORS, L. Burt, COBBS, C. Glenn, BRITT, William J

“…Malignant gliomas are the most common primary brain tumors in adults, have no known etiology, and are generally rapidly fatal despite current therapies. Human…”
Get full text

HuR, a RNA stability factor, is expressed in malignant brain tumors and binds to adenine- and uridine-rich elements within the 3' untranslated regions of cytokine and angiogenic factor mRNAs by NABORS, L. Burt, GILLESPIE, G. Yancey, HARKINS, Lualhati, KING, Peter H

“…Tumors of the central nervous system (CNS) often have sustained expression of labile genes, including angiogenic growth factors and immunosuppressive…”
Get full text

Prognostic Value of 1p, 19q, 9p, 10q, and EGFR-FISH Analyses in Recurrent Oligodendrogliomas by FALLON, KENNETH B, PALMER, CHERYL A, ROTH, KEVIN A, NABORS, L BURTON, WANG, WENQUAN, CARPENTER, MARK, BANERJEE, RUMA, FORSYTH, PETER, RICH, KEITH, PERRY, ARIE

“…Although 1p/19q codeletions define “genetically favorable” oligodendrogliomas, eventual tumor progression and patient death remain constant. Genetic testing is…”
Get full text

Analysis of the 5′ end of the mouse Elavl1 ( mHuA) gene reveals a transcriptional regulatory element and evidence for conserved genomic organization by King, P.H., Fuller, J.J., Nabors, L.B., Detloff, P.J.

“…mHuA ( Elavl1) belongs to a highly conserved family of genes encoding RNA-binding proteins and has been linked to cell growth and proliferation through its…”
Get full text

A unique neuronal organization in the cat pretectum revealed by antibodies to the calcium-binding protein calbindin-D 28K by Nabors, LB, Mize, RR

“…The pretectum is an important center for visual reflexes. However, the location, boundaries, and connections of individual nuclei of the pretectum are…”
Get full text

Erratum to: Cancer susceptibility variants and the risk of adult glioma in a US case–control study by Egan, Kathleen M., Thompson, Reid C., Nabors, L. B., Olson, Jeffrey J., Brat, Daniel J., LaRocca, Renato V., Brem, Steven, Moots, Paul L., Madden, Melissa H., Browning, James E., Chen, Y. Ann

Get full text

Amyotrophic Lateral Sclerosis-linked Mutant SOD1 Sequesters Hu Antigen R (HuR) and TIA-1-related Protein (TIAR) by Lu, Liang, Wang, Shuying, Zheng, Lei, Li, Xuelin, Suswam, Esther A., Zhang, Xiaowen, Wheeler, Crystal G., Nabors, L.B., Filippova, Natalia, King, Peter H.

“…Down-regulation of vascular endothelial growth factor (VEGF) in the mouse leads to progressive and selective degeneration of motor neurons similar to…”
Get full text

Assessment of brain tumor angiogenesis inhibitors using perfusion magnetic resonance imaging: Quality and analysis results of a phase I trial by Akella, N. Shastry, Twieg, Donald B., Mikkelsen, Tom, Hochberg, Fred H., Grossman, Stuart, Cloud, Gretchen A., Nabors, L. Burt

“…Purpose To determine thresholds of quality for a T2*‐weighted perfusion magnetic resonance imaging (MRI) study and evaluate the effects of an angiogenesis…”
Get full text

Long-term effects of cilengitide, a novel integrin inhibitor, in recurrent glioblastoma: A randomized phase IIa study by Fink, K., Mikkelsen, T., Nabors, L. B., Ravin, P., Plotkin, S. R., Schiff, D., Hicking, C., Picard, M., Reardon, D. A.

“…Abstract only…”
Get full text