Search Results - "Nabil, F"

Mucogingival conditions in the natural dentition: Narrative review, case definitions, and diagnostic considerations by Cortellini, Pierpaolo, Bissada, Nabil F.

“…Background Mucogingival deformities, and gingival recession in particular, are a group of conditions that affect a large number of patients. Since life…”
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Mucogingival conditions in the natural dentition: Narrative review, case definitions, and diagnostic considerations by Cortellini, Pierpaolo, Bissada, Nabil F.

“…Background Mucogingival deformities, and gingival recession in particular, are a group of conditions that affect a large number of patients. Since life…”
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Immunotherapeutics in nasopharyngeal carcinoma: a relentless CONTINUUM of success by Saba, Nabil F

“…The observed increase in expression of effector and exhaustion markers, including PD-1 and CTLA4, on tumour infiltrating lymphocytes support the use of immune…”
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An update on larynx cancer by Steuer, Conor E., El‐Deiry, Mark, Parks, Jason R., Higgins, Kristin A., Saba, Nabil F.

“…Answer questions and earn CME/CNE Laryngeal cancer remains one of the most common tumors of the respiratory tract. Fortunately, significant advancements have…”
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Head and neck cancer by Mody, Mayur D, Rocco, James W, Yom, Sue S, Haddad, Robert I, Saba, Nabil F

“…Head and neck cancer is the seventh most common type of cancer worldwide and comprise of a diverse group of tumours affecting the upper aerodigestive tract…”
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Preoperative chemotherapy for sinonasal squamous cell carcinoma (SNSCC): Time to move closer to a definitive answer by Saba, Nabil F.

“…Although results from this retrospective series suggest that preoperative chemotherapy may offer a benefit to organ preservation in sinonasal squamous cell…”
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Pembrolizumab for Platinum- and Cetuximab-Refractory Head and Neck Cancer: Results From a Single-Arm, Phase II Study by Bauml, Joshua, Seiwert, Tanguy Y, Pfister, David G, Worden, Francis, Liu, Stephen V, Gilbert, Jill, Saba, Nabil F, Weiss, Jared, Wirth, Lori, Sukari, Ammar, Kang, Hyunseok, Gibson, Michael K, Massarelli, Erminia, Powell, Steven, Meister, Amy, Shu, Xinxin, Cheng, Jonathan D, Haddad, Robert

“…Purpose There are no approved treatments for recurrent/metastatic head and neck squamous cell carcinoma refractory to platinum and cetuximab. In the…”
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Phase II Randomized Trial of Transoral Surgery and Low-Dose Intensity Modulated Radiation Therapy in Resectable p16+ Locally Advanced Oropharynx Cancer: An ECOG-ACRIN Cancer Research Group Trial (E3311) by Ferris, Robert L, Flamand, Yael, Weinstein, Gregory S, Li, Shuli, Quon, Harry, Mehra, Ranee, Garcia, Joaquin J, Chung, Christine H, Gillison, Maura L, Duvvuri, Umamaheswar, O'Malley, Jr, Bert W, Ozer, Enver, Thomas, Giovana R, Koch, Wayne M, Gross, Neil D, Bell, R Bryan, Saba, Nabil F, Lango, Miriam, Méndez, Eduardo, Burtness, Barbara

“…Definitive or postoperative chemoradiation (CRT) is curative for human papillomavirus-associated (HPV+) oropharynx cancer (OPC) but induces significant…”
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Palbociclib and cetuximab in platinum-resistant and in cetuximab-resistant human papillomavirus-unrelated head and neck cancer: a multicentre, multigroup, phase 2 trial by Adkins, Douglas, Prof, Ley, Jessica, BS, Neupane, Prakash, MD, Worden, Francis, Prof, Sacco, Assuntina G, MD, Palka, Kevin, MD, Grilley-Olson, Juneko E, MD, Maggiore, Ronald, MD, Salama, Noha N, PhD, Trinkaus, Kathryn, PhD, Van Tine, Brian A, MD, Steuer, Conor E, MD, Saba, Nabil F, Prof, Oppelt, Peter, MD

“…SummaryBackgroundMost head and neck squamous-cell carcinomas (HNSCCs) are driven by p16 INK4A inactivation and cyclin D1 overexpression that results in…”
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An update on the immune landscape in lung and head and neck cancers by Carlisle, Jennifer W., Steuer, Conor E., Owonikoko, Taofeek K., Saba, Nabil F.

“…Immunotherapy has dramatically changed the treatment landscape for patients with cancer. Programmed death–ligand 1/programmed death‐1 checkpoint inhibitors…”
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The diverse functions of FAT1 in cancer progression: good, bad, or ugly? by Chen, Zhuo Georgia, Saba, Nabil F, Teng, Yong

“…FAT atypical cadherin 1 (FAT1) is among the most frequently mutated genes in many types of cancer. Its highest mutation rate is found in head and neck squamous…”
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Periodontal manifestations of systemic diseases and developmental and acquired conditions: Consensus report of workgroup 3 of the 2017 World Workshop on the Classification of Periodontal and Peri‐Implant Diseases and Conditions by Jepsen, Søren, Caton, Jack G., Albandar, Jasim M., Bissada, Nabil F., Bouchard, Philippe, Cortellini, Pierpaolo, Demirel, Korkud, Sanctis, Massimo, Ercoli, Carlo, Fan, Jingyuan, Geurs, Nicolaas C., Hughes, Francis J., Jin, Lijian, Kantarci, Alpdogan, Lalla, Evanthia, Madianos, Phoebus N., Matthews, Debora, McGuire, Michael K., Mills, Michael P., Preshaw, Philip M., Reynolds, Mark A., Sculean, Anton, Susin, Cristiano, West, Nicola X., Yamazaki, Kazuhisa

“…Background A variety of systemic diseases and conditions can affect the course of periodontitis or have a negative impact on the periodontal attachment…”
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Management of locally recurrent nasopharyngeal carcinoma by Lee, Anne W.M., Ng, Wai Tong, Chan, Jimmy Y.W., Corry, June, Mäkitie, Antti, Mendenhall, William M., Rinaldo, Alessandra, Rodrigo, Juan P., Saba, Nabil F., Strojan, Primož, Suárez, Carlos, Vermorken, Jan B., Yom, Sue S., Ferlito, Alfio

“…•Regular surveillance monitoring is needed for early detection of local recurrence.•Surgery should be considered whenever feasible due to its lower…”
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Periodontal manifestations of systemic diseases and developmental and acquired conditions: Consensus report of workgroup 3 of the 2017 World Workshop on the Classification of Periodontal and Peri‐Implant Diseases and Conditions by Jepsen, Søren, Caton, Jack G., Albandar, Jasim M., Bissada, Nabil F., Bouchard, Philippe, Cortellini, Pierpaolo, Demirel, Korkud, Sanctis, Massimo, Ercoli, Carlo, Fan, Jingyuan, Geurs, Nicolaas C., Hughes, Francis J., Jin, Lijian, Kantarci, Alpdogan, Lalla, Evanthia, Madianos, Phoebus N., Matthews, Debora, McGuire, Michael K., Mills, Michael P., Preshaw, Philip M., Reynolds, Mark A., Sculean, Anton, Susin, Cristiano, West, Nicola X., Yamazaki, Kazuhisa

“…Background A variety of systemic diseases and conditions can affect the course of periodontitis or have a negative impact on the periodontal attachment…”
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Defining HPV-specific B cell responses in patients with head and neck cancer by Wieland, Andreas, Patel, Mihir R., Cardenas, Maria A., Eberhardt, Christiane S., Hudson, William H., Obeng, Rebecca C., Griffith, Christopher C., Wang, Xu, Chen, Zhuo G., Kissick, Haydn T., Saba, Nabil F., Ahmed, Rafi

“…Tumours often contain B cells and plasma cells but the antigen specificity of these intratumoral B cells is not well understood 1 – 8 . Here we show that human…”
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Functional HPV-specific PD-1+ stem-like CD8 T cells in head and neck cancer by Eberhardt, Christiane S., Kissick, Haydn T., Patel, Mihir R., Cardenas, Maria A., Prokhnevska, Nataliya, Obeng, Rebecca C., Nasti, Tahseen H., Griffith, Christopher C., Im, Se Jin, Wang, Xu, Shin, Dong M., Carrington, Mary, Chen, Zhuo G., Sidney, John, Sette, Alessandro, Saba, Nabil F., Wieland, Andreas, Ahmed, Rafi

“…T cells are important in tumour immunity but a better understanding is needed of the differentiation of antigen-specific T cells in human cancer 1 , 2 . Here…”
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Nivolumab Plus Ipilimumab Versus EXTREME Regimen as First-Line Treatment for Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck: The Final Results of CheckMate 651 by Haddad, Robert I, Harrington, Kevin, Tahara, Makoto, Ferris, Robert L, Gillison, Maura, Fayette, Jerome, Daste, Amaury, Koralewski, Piotr, Zurawski, Bogdan, Taberna, Miren, Saba, Nabil F, Mak, Milena, Kawecki, Andrzej, Girotto, Gustavo, Alvarez Avitia, Miguel Angel, Even, Caroline, Toledo, Joaquin Gabriel Reinoso, Guminski, Alexander, Müller-Richter, Urs, Kiyota, Naomi, Roberts, Mustimbo, Khan, Tariq Aziz, Miller-Moslin, Karen, Wei, Li, Argiris, Athanassios

“…CheckMate 651 (ClinicalTrials.gov identifier: NCT02741570) evaluated first-line nivolumab plus ipilimumab versus EXTREME (cetuximab plus cisplatin/carboplatin…”
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Nivolumab vs investigator’s choice in recurrent or metastatic squamous cell carcinoma of the head and neck: 2-year long-term survival update of CheckMate 141 with analyses by tumor PD-L1 expression by Ferris, Robert L., Blumenschein, George, Fayette, Jerome, Guigay, Joel, Colevas, A. Dimitrios, Licitra, Lisa, Harrington, Kevin J., Kasper, Stefan, Vokes, Everett E., Even, Caroline, Worden, Francis, Saba, Nabil F., Docampo, Lara Carmen Iglesias, Haddad, Robert, Rordorf, Tamara, Kiyota, Naomi, Tahara, Makoto, Lynch, Mark, Jayaprakash, Vijayvel, Li, Li, Gillison, Maura L.

“…•Nivolumab showed prolonged OS benefit in patients with R/M SCCHN post-platinum.•Long-term OS benefit was observed irrespective of PD-L1 expression or HPV…”
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Autosomal dominant VCP hypomorph mutation impairs disaggregation of PHF-tau by Darwich, Nabil F, Phan, Jessica M, Kim, Boram, Suh, EunRan, Papatriantafyllou, John D, Changolkar, Lakshmi, Nguyen, Aivi T, O'Rourke, Caroline M, He, Zhuohao, Porta, Sílvia, Gibbons, Garrett S, Luk, Kelvin C, Papageorgiou, Sokratis G, Grossman, Murray, Massimo, Lauren, Irwin, David J, McMillan, Corey T, Nasrallah, Ilya M, Toro, Camilo, Aguirre, Geoffrey K, Van Deerlin, Vivianna M, Lee, Edward B

“…Neurodegeneration in Alzheimer's disease (AD) is closely associated with the accumulation of pathologic tau aggregates in the form of neurofibrillary tangles…”
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Time to Rethink Our Strategy With a Preoperative Intensification Approach by Saba, Nabil F.

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