Search Results - "Nabais, Marta F"
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OSCA: a tool for omic-data-based complex trait analysis
Published in Genome Biology (28-05-2019)“…The rapid increase of omic data has greatly facilitated the investigation of associations between omic profiles such as DNA methylation (DNAm) and complex…”
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An overview of DNA methylation-derived trait score methods and applications
Published in Genome Biology (16-02-2023)“…Microarray technology has been used to measure genome-wide DNA methylation in thousands of individuals. These studies typically test the associations between…”
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Assessing the co-variability of DNA methylation across peripheral cells and tissues: Implications for the interpretation of findings in epigenetic epidemiology
Published in PLoS genetics (19-03-2021)“…Most epigenome-wide association studies (EWAS) quantify DNA methylation (DNAm) in peripheral tissues such as whole blood to identify positions in the genome…”
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Association between DNA methylation variability and self-reported exposure to heavy metals
Published in Scientific reports (22-06-2022)“…Individuals encounter varying environmental exposures throughout their lifetimes. Some exposures such as smoking are readily observed and have high personal…”
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Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3/TNIP1
Published in Genome medicine (19-01-2022)“…Amyotrophic lateral sclerosis (ALS) is a complex, late-onset, neurodegenerative disease with a genetic contribution to disease liability. Genome-wide…”
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Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis
Published in Npj genomic medicine (27-02-2020)“…We conducted DNA methylation association analyses using Illumina 450K data from whole blood for an Australian amyotrophic lateral sclerosis (ALS) case–control…”
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Analysis of DNA methylation associates the cystine–glutamate antiporter SLC7A11 with risk of Parkinson’s disease
Published in Nature communications (06-03-2020)“…An improved understanding of etiological mechanisms in Parkinson’s disease (PD) is urgently needed because the number of affected individuals is projected to…”
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Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis
Published in Npj genomic medicine (27-02-2020)“…We conducted DNA methylation association analyses using Illumina 450K data from whole blood for an Australian amyotrophic lateral sclerosis (ALS) case-control…”
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Journal Article