Search Results - "NYMAN, S"

The Role of Water Compartments in the Material Properties of Cortical Bone by Granke, Mathilde, Does, Mark D., Nyman, Jeffry S.

“…Comprising ~20 % of the volume, water is a key determinant of the mechanical behavior of cortical bone. It essentially exists in two general compartments:…”
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The Role of Matrix Composition in the Mechanical Behavior of Bone by Unal, Mustafa, Creecy, Amy, Nyman, Jeffry S.

“…Purpose of Review While thinning of the cortices or trabeculae weakens bone, age-related changes in matrix composition also lower fracture resistance. This…”
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Callus γδ T cells and microbe-induced intestinal Th17 cells improve fracture healing in mice by Dar, Hamid Y, Perrien, Daniel S, Pal, Subhashis, Stoica, Andreea, Uppuganti, Sasidhar, Nyman, Jeffry S, Jones, Rheinallt M, Weitzmann, M Neale, Pacifici, Roberto

“…IL-17A (IL-17), a driver of the inflammatory phase of fracture repair, is produced locally by several cell lineages including γδ T cells and Th17 cells…”
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Psychosocial impact of visual impairment in working-age adults by Nyman, S R, Gosney, M A, Victor, C R

“…To review the evidence for the presence of lower levels of psychosocial well-being in working-age adults with visual impairment and for interventions to…”
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Research advances in the use of tetrapyrrolic photosensitizers for photodynamic therapy by Nyman, Emma S, Hynninen, Paavo H

“…Photodynamic therapy (PDT) is a promising new treatment modality for several diseases, most notably cancer. In PDT, light, O 2, and a photosensitizing drug are…”
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MRI-derived bound and pore water concentrations as predictors of fracture resistance by Manhard, Mary Kate, Uppuganti, Sasidhar, Granke, Mathilde, Gochberg, Daniel F, Nyman, Jeffry S, Does, Mark D

“…Abstract Accurately predicting fracture risk in the clinic is challenging because the determinants are multi-factorial. A common approach to fracture risk…”
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The effects of rhBMP-2 released from biodegradable polyurethane/microsphere composite scaffolds on new bone formation in rat femora by Li, Bing, Yoshii, Toshitaka, Hafeman, Andrea E, Nyman, Jeffry S, Wenke, Joseph C, Guelcher, Scott A

“…Abstract Scaffolds prepared from biodegradable polyurethanes (PUR) have been investigated as a supportive matrix and delivery system for skin, cardiovascular,…”
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The use of nanoindentation for characterizing the properties of mineralized hard tissues: State-of-the art review by Lewis, Gladius, Nyman, Jeffry S.

“…The use of nanoindentation to determine nanomechanical properties of mineralized tissues has been investigated extensively. A detailed, critical, and…”
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The influence of water removal on the strength and toughness of cortical bone by Nyman, Jeffry S., Roy, Anuradha, Shen, Xinmei, Acuna, Rae L., Tyler, Jerrod H., Wang, Xiaodu

“…Although the effects of dehydration on the mechanical behavior of cortical bone are known, the underlying mechanisms for such effects are not clear. We…”
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Loss of Function of Lysosomal Acid Lipase (LAL) Profoundly Impacts Osteoblastogenesis and Increases Fracture Risk in Humans by Helderman, Ron C., Whitney, Daniel G., Duta-Mare, Madalina, Akhmetshina, Alena, Vujic, Nemanja, Jayapalan, Shobana, Nyman, Jeffry S., Misra, Biswapriya B., Rosen, Clifford J., Czech, Michael P., Kratky, Dagmar, Rendina-Ruedy, Elizabeth

“…Lysosomal acid lipase (LAL) is essential for cholesteryl ester (CE) and triacylglycerol (TAG) hydrolysis in lysosomes. Clinically, an autosomal recessive LIPA…”
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Type 1 Diabetes in Young Rats Leads to Progressive Trabecular Bone Loss, Cessation of Cortical Bone Growth, and Diminished Whole Bone Strength and Fatigue Life by Silva, Matthew J, Brodt, Michael D, Lynch, Michelle A, McKenzie, Jennifer A, Tanouye, Kristi M, Nyman, Jeffry S, Wang, Xiaodu

“…People with diabetes have increased risk of fracture disproportionate to BMD, suggesting reduced material strength (quality). We quantified the skeletal…”
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Cortical bone mechanical properties are altered in an animal model of progressive chronic kidney disease by Newman, Christopher L, Moe, Sharon M, Chen, Neal X, Hammond, Max A, Wallace, Joseph M, Nyman, Jeffry S, Allen, Matthew R

“…Chronic kidney disease (CKD), which leads tocortical bone loss and increasedporosity,increases therisk of fracture. Animal models have confirmed that these…”
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Fibrinolysis is essential for fracture repair and prevention of heterotopic ossification by Yuasa, Masato, Mignemi, Nicholas A, Nyman, Jeffry S, Duvall, Craig L, Schwartz, Herbert S, Okawa, Atsushi, Yoshii, Toshitaka, Bhattacharjee, Gourab, Zhao, Chenguang, Bible, Jesse E, Obremskey, William T, Flick, Matthew J, Degen, Jay L, Barnett, Joey V, Cates, Justin M M, Schoenecker, Jonathan G

“…Bone formation during fracture repair inevitably initiates within or around extravascular deposits of a fibrin-rich matrix. In addition to a central role in…”
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T 1 relaxation of bound and pore water in cortical bone by Ketsiri, Thammathida, Uppuganti, Sasidhar, Harkins, Kevin D, Gochberg, Daniel F, Nyman, Jeffry S, Does, Mark D

“…MRI measures of bound and/or pore water concentration in cortical bone offer potential diagnostics of bone fracture risk. The transverse relaxation…”
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Differential effects between the loss of MMP‐2 and MMP‐9 on structural and tissue‐level properties of bone by Nyman, Jeffry S, Lynch, Conor C, Perrien, Daniel S, Thiolloy, Sophie, O'Quinn, Elizabeth C, Patil, Chetan A, Bi, Xiaohong, Pharr, George M, Mahadevan‐Jansen, Anita, Mundy, Gregory R

“…Matrix metalloproteinases (MMPs) are capable of processing certain components of bone tissue, including type 1 collagen, a determinant of the biomechanical…”
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Unexpected timely fracture union in matrix metalloproteinase 9 deficient mice by Yuasa, Masato, Saito, Masanori, Molina, Cesar, Moore-Lotridge, Stephanie N, Benvenuti, Michael A, Mignemi, Nicholas A, Okawa, Atsushi, Yoshii, Toshitaka, Schwartz, Herbert S, Nyman, Jeffry S, Schoenecker, Jonathan G

“…Immediately following a fracture, a fibrin laden hematoma is formed to prevent bleeding and infection. Subsequently, the organized removal of fibrin, via the…”
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Micro-computed tomography assessment of the progression of fracture healing in mice by O'Neill, Kevin R, Stutz, Christopher M, Mignemi, Nicholas A, Burns, Michael C, Murry, Matthew R, Nyman, Jeffry S, Schoenecker, Jonathan G

“…Abstract The mouse fracture model is ideal for research into the pathways of healing because of the availability of genetic and transgenic mice and the ability…”
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Aalto-1, multi-payload CubeSat: In-orbit results and lessons learned by Mughal, M. Rizwan, Praks, J., Vainio, R., Janhunen, P., Envall, J., Näsilä, A., Oleynik, P., Niemelä, P., Nyman, S., Slavinskis, A., Gieseler, J., Jovanovic, N., Riwanto, B., Toivanen, P., Leppinen, H., Tikka, T., Punkkinen, A., Punkkinen, R., Hedman, H.-P., Lill, J.-O., Slotte, J.M.K.

“…The in-orbit results and lessons learned of the first Finnish satellite Aalto-1 are briefly presented in this paper. Aalto-1, a three-unit CubeSat which was…”
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The impact of SGLT2 inhibitors, compared with insulin, on diabetic bone disease in a mouse model of type 1 diabetes by Thrailkill, Kathryn M., MD, Nyman, Jeffry S., PhD, Bunn, R. Clay, PhD, Uppuganti, Sasidhar, MS, Thompson, Katherine L., PhD, Lumpkin, Charles K., PhD, Kalaitzoglou, Evangelia, MD, Fowlkes, John L., MD

“…Abstract Skeletal co-morbidities in type 1 diabetes include an increased risk for fracture and delayed fracture healing, which are intertwined with disease…”
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Patch Testing with Propolis of Different Geographical Origins in a Baseline Series by Nyman, Gunnar S. A., Giménez‐Arnau, Ana Maria, Grigaitiene, Jurate, Malinauskiene, Laura, Paulsen, Evy, Hagvall, Lina

“…The chemical composition of propolis varies with geographical origin; however, it is not known whether this affects the frequency of contact allergy to…”
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