Search Results - "NUTT, John G"
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Freezing of gait: moving forward on a mysterious clinical phenomenon
Published in Lancet neurology (01-08-2011)“…Summary Freezing of gait (FoG) is a unique and disabling clinical phenomenon characterised by brief episodes of inability to step or by extremely short steps…”
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Higher-level gait disorders: An open frontier
Published in Movement disorders (15-09-2013)“…ABSTRACT The term higher‐level gait disorders (HLGD) defines a category of balance and gait disorders that are not explained by deficits in strength, tone,…”
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Freezing of gait: a practical approach to management
Published in Lancet neurology (01-07-2015)“…Summary Freezing of gait is a common and disabling symptom in patients with parkinsonism, characterised by sudden and brief episodes of inability to produce…”
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Framework for understanding balance dysfunction in Parkinson's disease
Published in Movement disorders (15-09-2013)“…ABSTRACT People with Parkinson's disease (PD) suffer from progressive impairment in their mobility. Locomotor and balance dysfunction that impairs mobility in…”
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The Clinical Significance Of Freezing While Turning in Parkinson’s Disease
Published in Neuroscience (20-02-2017)“…Highlights • The validity of an objective measure of freezing during turning in place and TUG is investigated. • Turning in place consistently elicited…”
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How to Select Balance Measures Sensitive to Parkinson's Disease from Body-Worn Inertial Sensors-Separating the Trees from the Forest
Published in Sensors (Basel, Switzerland) (28-07-2019)“…This study aimed to determine the most sensitive objective measures of balance dysfunction that differ between people with Parkinson's Disease (PD) and healthy…”
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Neurological disorders of gait, balance and posture: a sign-based approach
Published in Nature reviews. Neurology (01-03-2018)“…In this article, Nonnekes and colleagues offer a new approach to the diagnosis of neurological disorders associated with altered gait, balance and posture…”
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Functional reorganization of the locomotor network in Parkinson patients with freezing of gait
Published in PloS one (17-06-2014)“…Freezing of gait (FoG) is a transient inability to initiate or maintain stepping that often accompanies advanced Parkinson's disease (PD) and significantly…”
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Postural sway as a marker of progression in Parkinson's disease: A pilot longitudinal study
Published in Gait & posture (01-07-2012)“…Highlights ► Objective sway measures deteriorated over one year. ► UPDRS motor scores did not show significant changes over one year. ► Medio-lateral (ML) sway…”
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Measuring freezing of gait during daily-life: an open-source, wearable sensors approach
Published in Journal of neuroengineering and rehabilitation (04-01-2021)“…Although a growing number of studies focus on the measurement and detection of freezing of gait (FoG) in laboratory settings, only a few studies have attempted…”
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Laboratory versus daily life gait characteristics in patients with multiple sclerosis, Parkinson's disease, and matched controls
Published in Journal of neuroengineering and rehabilitation (01-12-2020)“…Recent findings suggest that a gait assessment at a discrete moment in a clinic or laboratory setting may not reflect functional, everyday mobility. As a step…”
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Digital measures of freezing of gait across the spectrum of normal, non-freezers, possible freezers and definite freezers
Published in Journal of neurology (01-09-2023)“…Over the course of the disease, freezing of gait (FoG) will gradually impact over 80% of people with Parkinson’s disease (PD). Clinical decision-making and…”
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The Unified Dyskinesia Rating Scale: Presentation and clinimetric profile
Published in Movement disorders (15-12-2008)“…We developed and tested a rating scale aimed to capture the essential features of dyskinesia in Parkinson's disease (PD). Although several scales assess…”
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Trunk accelerometry reveals postural instability in untreated Parkinson’s disease
Published in Parkinsonism & related disorders (01-08-2011)“…Abstract While several studies have shown that subjects with advanced Parkinson’s disease (PD) exhibit abnormalities in sway parameters during quiet standing,…”
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Addressing the Challenges of Clinical Research for Freezing of Gait in Parkinson's Disease
Published in Movement disorders (01-02-2022)Get full text
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Effects of a central cholinesterase inhibitor on reducing falls in Parkinson disease
Published in Neurology (05-10-2010)“…To investigate if a central cholinesterase inhibitor will reduce falling frequency in subjects with Parkinson disease (PD) with advanced postural instability…”
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Pharmacokinetics and pharmacodynamics of levodopa
Published in Movement disorders (2008)“…The pharmacokinetics and pharmacodynamics of levodopa are dominated by two features: the short plasma half‐life of the drug and the portion of the…”
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Continuous monitoring of turning in Parkinson's disease: Rehabilitation potential
Published in NeuroRehabilitation (Reading, Mass.) (22-08-2015)“…Difficulty turning during gait is a major contributor to mobility disability, falls and reduced quality of life in patients with Parkinson's disease (PD)…”
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Cognitively Challenging Agility Boot Camp Program for Freezing of Gait in Parkinson Disease
Published in Neurorehabilitation and neural repair (01-05-2020)“…Introduction. It is well documented that freezing of gait (FoG) episodes occur in situations that are mentally challenging, such as dual tasks, consistent with…”
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Effect of Bout Length on Gait Measures in People with and without Parkinson's Disease during Daily Life
Published in Sensors (Basel, Switzerland) (12-10-2020)“…Although the use of wearable technology to characterize gait disorders in daily life is increasing, there is no consensus on which specific gait bout length…”
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