Search Results - "NUTHULAGANTI, Parvathi"

Receptor for the Pain Modulatory Neuropeptides FF and AF Is an Orphan G Protein-coupled Receptor by Elshourbagy, N A, Ames, R S, Fitzgerald, L R, Foley, J J, Chambers, J K, Szekeres, P G, Evans, N A, Schmidt, D B, Buckley, P T, Dytko, G M, Murdock, P R, Milligan, G, Groarke, D A, Tan, K B, Shabon, U, Nuthulaganti, P, Wang, D Y, Wilson, S, Bergsma, D J, Sarau, H M

“…Opiate tolerance and dependence are major clinical and social problems. The anti-opiate neuropeptides FF and AF (NPFF and NPAF) have been implicated in pain…”
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Identification, molecular cloning, expression, and characterization of a cysteinyl leukotriene receptor by Sarau, H M, Ames, R S, Chambers, J, Ellis, C, Elshourbagy, N, Foley, J J, Schmidt, D B, Muccitelli, R M, Jenkins, O, Murdock, P R, Herrity, N C, Halsey, W, Sathe, G, Muir, A I, Nuthulaganti, P, Dytko, G M, Buckley, P T, Wilson, S, Bergsma, D J, Hay, D W

“…The cysteinyl leukotrienes (CysLTs) have been implicated in the pathophysiology of inflammatory disorders, in particular asthma, for which the CysLT receptor…”
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The peptidic urotensin‐II receptor ligand GSK248451 possesses less intrinsic activity than the low‐efficacy partial agonists SB‐710411 and urantide in native mammalian tissues and recombinant cell systems by Behm, David J, Stankus, Gerald, Doe, Christopher P A, Willette, Robert N, Sarau, Henry M, Foley, James J, Schmidt, Dulcie B, Nuthulaganti, Parvathi, Fornwald, James A, Ames, Robert S, Lambert, David G, Calo', Girolamo, Camarda, Valeria, Aiyar, Nambi V, Douglas, Stephen A

“…1 Several peptidic urotensin‐II (UT) receptor antagonists exert ‘paradoxical’ agonist activity in recombinant cell‐ and tissue‐based bioassay systems, likely…”
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M3 muscarinic acetylcholine receptor antagonists : SAR and optimization of bi-aryl amines by BUDZIK, Brian, YONGHUI WANG, SARAU, Henry M, MORROW, Dwight M, MOORE, Michael L, RIVERO, Ralph A, PALOVICH, Michael, SALMON, Michael, BELMONTE, Kristen E, LAINE, Dramane I, JIAN JIN, DONGCHUAN SHI, FENG WANG, HAIBO XIE, ZEHONG WAN, CHONGYE ZHU, FOLEY, James J, NUTHULAGANTI, Parvathi, KALLAL, Lorena A

“…Exploration of multiple regions of a bi-aryl amine template led to the identification of highly potent M(3) muscarinic acetylcholine receptor antagonists such…”
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Cloning and characterization of a human angiotensin II type 1 receptor by Bergsma, D J, Ellis, C, Kumar, C, Nuthulaganti, P, Kersten, H, Elshourbagy, N, Griffin, E, Stadel, J M, Aiyar, N

“…A human liver cDNA library was screened using a rat type 1 angiotensin II receptor cDNA coding sequence as a probe. cDNA clones were isolated which encoded a…”
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Cloning and characterization of a novel endothelin receptor from Xenopus heart by CHANDRIKA KUMAR, MWANGI, V, PARVATHI NUTHULAGANTI, HSIAO-LING WU, PULLEN, M, BRUN, K, HARISH AIYAR, MORRIS, R. A, NAUGHTON, R, NAMBI, P

“…Endothelin (ET) receptors display subtype heterogeneity and so far three subtypes of ET receptors, namely ETA, ETB, and ETC, have been identified, cloned,…”
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BacMam: versatile gene delivery technology for GPCR assays by Davenport, Elizabeth A, Nuthulaganti, Parvathi, Ames, Robert S

“…BacMam viruses are modified baculoviruses that contain mammalian expression cassettes for viral gene delivery and transient expression in mammalian cells. They…”
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BacMam recombinant baculoviruses in G protein-coupled receptor drug discovery by Ames, Robert, Fornwald, James, Nuthulaganti, Parvathi, Trill, John, Foley, James, Buckley, Peter, Kost, Thomas, Wu, Zining, Romanos, Michael

“…With completion of the sequencing of the human and mouse genomes, the primary sequences of close to 400 non-olfactory G protein-coupled receptors (GPCRs) have…”
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Cloning and characterization of a rabbit ortholog of human Gα16 and mouse Gα15 by Feild, John A., Foley, James J., Testa, Tania T., Nuthulaganti, Parvathi, Ellis, Catherine, Sarau, Henry M., Ames, Robert S.

“…A cDNA was cloned from a rabbit spleen cDNA library which encoded a G-protein α subunit peptide of 374 amino acids, that at the peptide level exhibited 86% and…”
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Cloning and Characterization of a Novel Integrin β3Subunit by Kumar, Chandrika S., James, Ian E., Wong, Angela, Mwangi, Vincent, Feild, John A., Nuthulaganti, Parvathi, Connor, Janice R., Eichman, Christopher, Ali, Fadia, Hwang, Shing Mei, Rieman, David J., Drake, Fred H., Gowen, Maxine

“…We have identified a novel integrin β3 subunit, termed β3C, from a human osteoclast cDNA library. The COOH-terminal sequence and 3′-untranslated region of the…”
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Identification and characterization of a novel endothelin receptor that binds both ETA- and ETB-selective ligands by Nambi, P, Pullen, M, Kincaid, J, Nuthulaganti, P, Aiyar, N, Brooks, D P, Gellai, M, Kumar, C

“…This study demonstrates the presence of a novel endothelin (ET) receptor subtype that displays high affinity for both ETA- and ETB-selective ligands. This…”
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Molecular and pharmacological characterization of the murine tachykinin NK3 receptor by SARAU, Henry M, FEILD, John A, GIARDINA, Giuseppe A. M, HAY, Douglas W. P, AMES, Robert S, FOLEY, James J, NUTHULAGANTI, Parvathi, SCHMIDT, Dulcie B, BUCKLEY, Peter T, ELSHOURBAGY, Nabil A, BRAWNER, Mary E, LUTTMANN, Mark A

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Heterologous expression of G protein-coupled receptors in U-2 OS osteosarcoma cells by Ames, Robert, Nuthulaganti, Parvathi, Fornwald, Jim, Shabon, Usman, van-der-Keyl, Harjeet, Elshourbagy, Nabil

“…Recombinant baculoviruses, in which the insect cell-specific polyhedrin promoter has been replaced with a mammalian cell-active expression cassette (BacMam…”
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Molecular and pharmacological characterization of the murine tachykinin NK 3 receptor by Sarau, Henry M, Feild, John A, Ames, Robert S, Foley, James J, Nuthulaganti, Parvathi, Schmidt, Dulcie B, Buckley, Peter T, Elshourbagy, Nabil A, Brawner, Mary E, Luttmann, Mark A, Giardina, Giuseppe A.M, Hay, Douglas W.P

“…Starting with a partial sequence from Genbank, polymerase chain reaction (PCR) was utilized to isolate the full-length cDNA for NK 3 receptor from mouse brain…”
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Dexamethasone down-regulates the expression of endothelin receptors in vascular smooth muscle cells by NAMBI, P, PULLEN, M, HSIAO-LING WU, NUTHULAGANTI, P, ELSHOURBAGY, N, KUMAR, C

“…Steroid hormones have been shown to modulate a number of physiological processes in addition to their potent antiinflammatory effects. Endothelin (ET) is a…”
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Isolation and expression of a novel angiotensin II receptor from Xenopus laevis heart by Bergsma, D J, Ellis, C, Nuthulaganti, P R, Nambi, P, Scaife, K, Kumar, C, Aiyar, N

“…A Xenopus laevis heart cDNA library was screened using the human angiotensin type 1 (AT1) receptor cDNA coding sequence as a hybridization probe. A cDNA was…”
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Cloning and Characterization of a Novel Integrin β3Subunit by Chandrika S. Kumar, Ian E. James, Angela Wong, Vincent Mwangi, John A. Feild, Parvathi Nuthulaganti, Janice R. Connor, Christopher Eichman, Fadia Ali, Shing Mei Hwang, David J. Rieman, Fred H. Drake, Maxine Gowen

“…We have identified a novel integrin β 3 subunit, termed β 3C , from a human osteoclast cDNA library. The COOH-terminal sequence and 3′-untranslated region…”
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Novel endothelin receptors in the follicular membranes of Xenopus laevis oocytes mediate calcium responses by signal transduction through gap junctions by Kumar, C S, Nuthulaganti, P, Pullen, M, Nambi, P

“…Follicular oocytes from Xenopus laevis display saturable and high affinity endothelin (ET)-1 binding sites. Competition binding experiments using unlabeled…”
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Absence of endothelin receptors and receptor mRNA in mammalian fibroblasts transformed with SV40 or ras oncogene by Nambi, P, Mattern, M R, Wu, H L, Pullen, M, Nuthulaganti, P, Hofmann, G A, Kumar, C

“…Endothelin-1 (ET-1), a peptide isolated from the culture medium of endothelial cells, mediates a variety of physiological and pathological responses including…”
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Characterization of a functional angiotensin II receptor in Xenopus laevis heart by Aiyar, N, Baker, E, Pullen, M, Nuthulaganti, P, Bergsma, D J, Kumar, C, Nambi, P

“…High-affinity (104 +/- 18 pmol/l) and high-density (204 +/- 25 fmol/mg) angiotensin II (AII) binding sites have been identified in Xenopus laevis heart…”
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