Search Results - "NURUN NABI, A. H. M"
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A comprehensive in silico investigation into the pathogenic SNPs in the RTEL1 gene and their biological consequences
Published in PloS one (06-09-2024)“…The Regulator of Telomere Helicase 1 (RTEL1) gene encodes a critical DNA helicase intricately involved in the maintenance of telomeric structures and the…”
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Whole exome sequencing uncovered highly penetrant recessive mutations for a spectrum of rare genetic pediatric diseases in Bangladesh
Published in Npj genomic medicine (16-02-2021)“…Collectively, rare genetic diseases affect a significant number of individuals worldwide. In this study, we have conducted whole-exome sequencing (WES) and…”
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Renal Sympathetic Denervation Suppresses De Novo Podocyte Injury and Albuminuria in Rats With Aortic Regurgitation
Published in Circulation (New York, N.Y.) (20-03-2012)“…The presence of chronic kidney disease is a significant independent risk factor for poor prognosis in patients with chronic heart failure. However, the…”
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Genetic variation of the transcription factor GATA3, not STAT4, is associated with the risk of type 2 diabetes in the Bangladeshi population
Published in PloS one (25-07-2018)“…Type 2 diabetes mellitus is a multifactorial metabolic disorder caused by environmental factors and has a strong association with hereditary issues. These…”
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Mapping the protein binding site of the (pro)renin receptor using in silico 3D structural analysis
Published in Hypertension research (01-04-2023)“…We have previously reported that monoclonal antibodies against the (pro)renin receptor [(P)RR] can reduce the Wnt/β-catenin-dependent development of pancreatic…”
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Intronic Variants of the Angiotensin-Converting Enzyme 2 Gene Modulate Plasma ACE2 Levels and Possibly Confer Protection against Severe COVID-19
Published in BioMed research international (2023)“…Membrane-bound angiotensin-converting enzyme 2 (ACE2) receptor acts as the entry point for the novel coronavirus, SARS-CoV-2. Polymorphisms in the ACE2 gene…”
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Multidrug Resistance Profiles and Resistance Mechanisms to β-Lactams and Fluoroquinolones in Bacterial Isolates from Hospital Wastewater in Bangladesh
Published in Current issues in molecular biology (01-08-2023)“…Multidrug resistance (MDR) is one of the deadliest public health concerns of the 21st century, rendering many powerful antibiotics ineffective. The current…”
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Slowly progressive, angiotensin II-Independent glomerulosclerosis in human (Pro)renin receptor-transgenic rats
Published in Journal of the American Society of Nephrology (01-06-2007)“…For defining the pathogenic effects of the (pro)renin receptor-transgenic rat, strains that overexpressed the human receptor were generated. Although…”
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Prorenin receptor blockade inhibits development of glomerulosclerosis in diabetic angiotensin II type 1a receptor-deficient mice
Published in Journal of the American Society of Nephrology (01-07-2006)“…Blockade of the renin-angiotensin system slows the progression of diabetic nephropathy but fails to abolish the development of end-stage nephropathy of…”
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The polymorphic landscape analysis of GATA1 exons uncovered the genetic variants associated with higher thrombocytopenia in dengue patients
Published in PLoS neglected tropical diseases (30-06-2022)“…The current study elucidated an association between gene variants and thrombocytopenia through the investigation of the exonic polymorphic landscape of…”
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Association study of leukocyte telomere length and genetic polymorphism within hTERT promoter with type 2 diabetes in Bangladeshi population
Published in Molecular biology reports (2021)“…Telomeres are protective cap on the ends of DNA of non-coding tandem repeats of TTAGGG. Human telomerase reverse transcriptase (hTERT) is a catalytic subunit…”
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Construction of copy number variation landscape and characterization of associated genes in a Bangladeshi cohort of neurodevelopmental disorders
Published in Frontiers in genetics (07-03-2023)“…Copy number variations (CNVs) play a critical role in the pathogenesis of neurodevelopmental disorders (NDD) among children. In this study, we aim to identify…”
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Non-coding Single Nucleotide Variants of Renin and the (Pro)renin Receptor are Associated with Polygenic Diseases in a Bangladeshi Population
Published in Biochemical genetics (01-10-2021)“…Non-coding variants or single-nucleotide polymorphisms (SNPs) play pivotal roles in orchestrating pathogeneses of polygenic diseases, including hypertension…”
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Functional Polymorphism Located in the microRNA Binding Site of the Insulin Receptor (INSR) Gene Confers Risk for Type 2 Diabetes Mellitus in the Bangladeshi Population
Published in Biochemical genetics (01-02-2019)“…Bangladesh has the second largest number of adults with diabetes in South Asia. Compelling evidence suggest that miRNAs contribute to the etiology of Type 2…”
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Correction to: Functional Polymorphism Located in the microRNA Binding Site of the Insulin Receptor (INSR) Gene Confers Risk for Type 2 Diabetes Mellitus in the Bangladeshi Population
Published in Biochemical genetics (01-02-2019)“…The original version of this article unfortunately contained a mistake in the co-author name. It should be Farhana Jahan instead of Farhan Jahan…”
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(Pro)Renin Receptor-Mediated Activation of Mitogen-Activated Protein Kinases in Human Vascular Smooth Muscle Cells
Published in Hypertension research (01-11-2007)“…Blockade of (pro)renin receptor has benefits in diabetic angiotensin II type-1a-receptor-deficient mice, suggesting the importance of (pro)renin…”
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Expression of functional human (pro)renin receptor in silkworm (Bombyx mori) larvae using BmMNPV bacmid
Published in Biotechnology and applied biochemistry (01-03-2008)“…The circulating RA (renin–angiotensin) system is essential for the regulation of blood pressure and electrolyte balance. Recently, plasma prorenin has been…”
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Analyses of Genetic Variations of Glutathione S-Transferase Mu1 and Theta1 Genes in Bangladeshi Tannery Workers and Healthy Controls
Published in BioMed research international (01-01-2016)“…Glutathione S-transferases (GSTs) belong to a group of multigene detoxification enzymes, which defend cells against oxidative stress. Tannery workers are at…”
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Association of respiratory complications and elevated serum immunoglobulins with drinking water arsenic toxicity in human
Published in Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering (01-10-2007)“…We assessed the relationship between chronic arsenic exposure through drinking water with respiratory complications and humoral immune response by measuring…”
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Prediction of Epitope-Based Peptides for the Utility of Vaccine Development from Fusion and Glycoprotein of Nipah Virus Using In Silico Approach
Published in Advances in Bioinformatics (2014)“…This study aims to design epitope-based peptides for the utility of vaccine development by targeting glycoprotein G and envelope protein F of Nipah virus (NiV)…”
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