Search Results - "NURSE, P"
-
1
Clipping of flexible tails of histones H3 and H4 affects the structure and dynamics of the nucleosome
Published in Biophysical journal (05-03-2013)“…Förster resonance energy transfer was used to monitor the dynamic conformations of mononucleosomes under different chromatin folding conditions to elucidate…”
Get full text
Journal Article -
2
DNA Methylation Effects on Tetra-Nucleosome Compaction and Aggregation
Published in Biophysical journal (07-10-2014)“…DNA CpG methylation has been associated with chromatin compaction and gene silencing. Whether DNA methylation directly contributes to chromatin compaction…”
Get full text
Journal Article -
3
Stochastic Hybrid Modeling of DNA Replication across a Complete Genome
Published in Proceedings of the National Academy of Sciences - PNAS (26-08-2008)“…DNA replication in eukaryotic cells initiates from hundreds of origins along their genomes, leading to complete duplication of genetic information before cell…”
Get full text
Journal Article -
4
A diffusion model for the coordination of DNA replication in Schizosaccharomyces pombe
Published in Scientific reports (05-01-2016)“…The locations of proteins and epigenetic marks on the chromosomal DNA sequence are believed to demarcate the eukaryotic genome into distinct structural and…”
Get full text
Journal Article -
5
Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates
Published in The EMBO journal (01-11-1991)“…The p34cdc2 protein kinase is a conserved regulator of the eukaryotic cell cycle. Here we show that residues Thr14 and Tyr15 of mouse p34cdc2 become…”
Get full text
Journal Article -
6
In vivo localisation of fission yeast cyclin-dependent kinase cdc2p and cyclin B cdc13p during mitosis and meiosis
Published in Journal of cell science (01-07-2001)“…We investigated the in vivo localisation of fission yeast cyclin-dependent kinase cdc2p during mitosis and meiosis. Fusion to yellow fluorescent protein (YFP)…”
Get full text
Journal Article -
7
Regulation of the eukaryotic cell cycle
Published in European Journal of Cancer (01-06-1997)“…THE CELL cycle is the process by which a cell ensures its correct reproduction, and is central to the understanding of all life. For a cell to survive, it is…”
Get full text
Book Review Conference Proceeding Journal Article -
8
Cdc18/CDC6 activates the Rad3-dependent checkpoint in the fission yeast
Published in Nucleic acids research (01-08-2007)“…A screen for genes that can ectopically activate a Rad3-dependent checkpoint block over mitosis in fission yeast has identified the DNA replication initiation…”
Get full text
Journal Article -
9
Meiotic DNA replication checkpoint control in fission yeast
Published in Genes & development (01-10-1999)“…In eukaryotes, the DNA replication checkpoint prevents entry into mitosis when DNA replication is incomplete and is crucial for maintaining genomic integrity…”
Get full text
Journal Article -
10
Understanding the cell cycle
Published in Nature medicine (01-10-1998)Get full text
Journal Article -
11
Genetic analysis of cell morphogenesis in fission yeast--a role for casein kinase II in the establishment of polarized growth
Published in The EMBO journal (01-05-1994)“…We have initiated a study to identify genes regulating cell morphogenesis in the fission yeast Schizosaccharomyces pombe. Five genes have been identified,…”
Get full text
Journal Article -
12
fission yeast RCC1-related protein is required for the mitosis to interphase transition
Published in The EMBO journal (01-02-1994)“…The isolation and characterization of the mutant dcd(ts) (defect in chromatin decondensation) has led to the identification of two conserved proteins required…”
Get full text
Journal Article -
13
Navigating The 2022 International Consensus and World Health Organization Classifications of Hematopathology: A Call for Unified Diagnostic Language
Published in Archives of pathology & laboratory medicine (1976) (02-07-2024)“…In 2022, 2 distinct guidelines for the diagnosis of myeloid neoplasms became available: the 5th edition of the World Health Organization guideline (WHO2022)…”
Get full text
Journal Article -
14
Effects of early palliative care integration on patients with newly diagnosed multiple myeloma
Published in Supportive care in cancer (01-07-2024)“…Purpose While numerous studies underscore the benefits of early palliative care (EPC) for patients with solid tumors, its effects on patients with multiple…”
Get full text
Journal Article -
15
Phosphorylation at Thr167 is required for Schizosaccharomyces pombe p34cdc2 function
Published in The EMBO journal (01-11-1991)“…Eukaryotic cell cycle progression requires the periodic activation and inactivation of a protein‐serine/threonine kinase which in fission yeast is encoded by…”
Get full text
Journal Article -
16
Fission yeast genes involved in coupling mitosis to completion of DNA replication
Published in Genes & development (01-11-1992)“…We have isolated fission yeast mutants that enter mitosis when DNA replication is blocked with hydroxyurea. The mutants define eight linkage groups, three of…”
Get full text
Journal Article -
17
The Incredible Life and Times of Biological Cells
Published in Science (American Association for the Advancement of Science) (08-09-2000)“…In this month's essay, Paul Nurse recapitulates the ontogeny of one of the most important theories in the history of biology, the cell theory, which proposes…”
Get full text
Journal Article -
18
License Withheld: Geminin Blocks DNA Replication
Published in Science (American Association for the Advancement of Science) (22-12-2000)“…For cells to survive they must receive a complete copy of their genome every time they divide. A process called licensing ensures that chromatin becomes…”
Get full text
Journal Article -
19
Fission yeast retrotransposon Tf1 integration is targeted to 5' ends of open reading frames
Published in Nucleic acids research (01-12-2000)“…Target site selection of transposable elements is usually not random but involves some specificity for a DNA sequence or a DNA binding host factor. We have…”
Get full text
Journal Article -
20
Cis and trans internucleosomal interactions of H3 and H4 tails in tetranucleosomes
Published in Biopolymers (01-01-2015)“…ABSTRACT Chromatin structure and the transcriptional state of a gene can be modulated by modifications made on H3 and H4 tails of histones. Elucidating the…”
Get full text
Journal Article