Search Results - "NURDEN, A. T."

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    Inherited platelet disorders by NURDEN, A. T., FRESON, K., SELIGSOHN, U.

    “…Inherited diseases of the megakaryocyte lineage give rise to bleeding when platelets fail to fulfill their hemostatic function upon vessel injury. Platelet…”
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    Journal Article
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    Platelet-released growth factors enhance the secretion of hyaluronic acid and induce hepatocyte growth factor production by synovial fibroblasts from arthritic patients by Anitua, E., Sánchez, M., Nurden, A. T., Zalduendo, M. M., de la Fuente, M., Azofra, J., Andía, I.

    Published in Rheumatology (Oxford, England) (01-12-2007)
    “…Objectives. Autologous platelet-secreted growth factors (GFs) may have therapeutic effects in osteoarthritis (OA) capsular joints via multiple mechanisms. Our…”
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    Qualitative disorders of platelets and megakaryocytes by NURDEN, A. T.

    Published in Journal of thrombosis and haemostasis (01-08-2005)
    “…Qualitative disorders of platelet function and production form a large group of rare diseases which cover a multitude of genetic defects that by and large have…”
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    Inherited disorders of platelet function: selected updates by Nurden, A. T., Nurden, P.

    Published in Journal of thrombosis and haemostasis (01-06-2015)
    “…Summary The gene variants responsible for the primary genotype of many platelet disorders have now been identified. Next‐generation sequencing technology…”
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    Diagnosis of suspected inherited platelet function disorders: results of a worldwide survey by Gresele, P., Harrison, P., Bury, L., Falcinelli, E., Gachet, C., Hayward, C. P., Kenny, D., Mezzano, D., Mumford, A. D., Nugent, D., Nurden, A. T., Orsini, S., Cattaneo, M.

    Published in Journal of thrombosis and haemostasis (01-09-2014)
    “…Summary Background Diagnosis of inherited platelet function disorders (IPFDs) is important for appropriate management and to improve epidemiologic and clinical…”
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    Annexin V as a Probe of Aminophospholipid Exposure and Platelet Membrane Vesiculation: A Flow Cytometry Study Showing a Role for Free Sulfhydryl Groups by Dachary-Prigent, Jeanne, Freyssinet, Jean-Marie, Pasquet, Jean-Max, Carron, Jean-Claude, Nurden, Alan T.

    Published in Blood (15-05-1993)
    “…Annexin V, a protein with a high affinity and a strict specificity for aminophospholipids at physiologic calcium concentrations, was used to probe platelet…”
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    Polymorphisms of human platelet membrane glycoproteins: structure and clinical significance by Nurden, A T

    Published in Thrombosis and haemostasis (01-07-1995)
    “…The haemostatic response of platelets of any one individual will be influenced by the genetic profile of the total population of receptors expressed on the…”
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    An adenine insertion in exon 6 of human GP6 generates a truncated protein associated with a bleeding disorder in four Chilean families by Matus, V., Valenzuela, G., Sáez, C. G., Hidalgo, P., Lagos, M., Aranda, E., Panes, O., Pereira, J., Pillois, X., Nurden, A. T., Mezzano, D.

    Published in Journal of thrombosis and haemostasis (01-09-2013)
    “…Summary Background Glycoprotein VI (GPVI), 60–65 kDa, is a major collagen receptor on platelet membranes involved in adhesive and signaling responses. Mice…”
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    Natural history of platelet antibody formation against αIIbβ3 in a French cohort of Glanzmann thrombasthenia patients by FIORE, M., FIRAH, N., PILLOIS, X., NURDEN, P., HEILIG, R., NURDEN, A. T.

    “…Treatment of the bleeding syndrome in Glanzmann thrombasthenia (GT) is often complicated by naturally occurring isoantibodies directed against the αIIbβ3…”
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    Induction of megakaryocytes to synthesize and store a releasable pool of human factor VIII by Wilcox, D. A., Shi, Q., Nurden, P., Haberichter, S. L., Rosenberg, J. B., Johnson, B. D., Nurden, A. T., Ii, G. C. White, Montgomery, R. R.

    Published in Journal of thrombosis and haemostasis (01-12-2003)
    “…von Willebrand factor (VWF) is a complex plasma glycoprotein that modulates platelet adhesion at the site of a vascular injury, and it also serves as a carrier…”
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