Search Results - "NUNES, Sofia"

Glutathione in Ovarian Cancer: A Double-Edged Sword by Nunes, Sofia C, Serpa, Jacinta

“…Glutathione (GSH) has several roles in a cell, such as a reactive oxygen species (ROS) scavenger, an intervenient in xenobiotics metabolism and a reservoir of…”
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Tumor Microenvironment - Selective Pressures Boosting Cancer Progression by Nunes, Sofia C

“…In 2018, 9.6 million deaths from cancer were estimated, being this disease the second leading cause of death worldwide. Notwithstanding all the efforts…”
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Cysteine Aminotransferase (CAT): A Pivotal Sponsor in Metabolic Remodeling and an Ally of 3-Mercaptopyruvate Sulfurtransferase (MST) in Cancer by Hipólito, Ana, Nunes, Sofia C, Vicente, João B, Serpa, Jacinta

“…Metabolic remodeling is a critical skill of malignant cells, allowing their survival and spread. The metabolic dynamics and adaptation capacity of cancer cells…”
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Cysteine allows ovarian cancer cells to adapt to hypoxia and to escape from carboplatin cytotoxicity by Nunes, Sofia C., Ramos, Cristiano, Lopes-Coelho, Filipa, Sequeira, Catarina O., Silva, Fernanda, Gouveia-Fernandes, Sofia, Rodrigues, Armanda, Guimarães, António, Silveira, Margarida, Abreu, Sofia, Santo, Vítor E., Brito, Catarina, Félix, Ana, Pereira, Sofia A., Serpa, Jacinta

“…Ovarian cancer is the second most common gynaecologic malignancy and the main cause of death from gynaecologic cancer, due to late diagnosis and…”
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Wnt Signaling: Paths for Cancer Progression by Carreira-Barbosa, Filipa, Nunes, Sofia C

“…The Wnt signaling pathways are well known for having several pivotal roles during embryonic development. However, the same developmental signaling pathways…”
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Eosinophilia in Amoxicillin-Induced Rash in Infectious Mononucleosis by Abreu, Ana, Nunes, Sofia, Botelho, Carmen

“…A link between amoxicillin-induced rash in infectious mononucleosis and allergy has been previously reported. However, the pathophysiological cause and aspects…”
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Cysteine boosters the evolutionary adaptation to CoCl2 mimicked hypoxia conditions, favouring carboplatin resistance in ovarian cancer by Nunes, Sofia C, Lopes-Coelho, Filipa, Gouveia-Fernandes, Sofia, Ramos, Cristiano, Pereira, Sofia A, Serpa, Jacinta

“…BACKGROUNDOvarian cancer is the second most common gynaecologic malignancy and the most common cause of death from gynaecologic cancer, especially due to…”
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Exploiting Cancer Cells Metabolic Adaptability to Enhance Therapy Response in Cancer by Nunes, Sofia C

“…Despite all the progresses developed in prevention and new treatment approaches, cancer is the second leading cause of death worldwide, being chemoresistance a…”
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Integrated ultra scale-down and multivariate analysis of flocculation and centrifugation for enhanced primary recovery by Nunes, Sofia L.V., Mannall, Gareth J., Rayat, Andrea C.M.E.

“…A linked ultra scale-down (USD) flocculation and centrifugation system facilitates rapid bioprocess development and evaluation. These techniques allow studies…”
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A diagnostic tool for assessing the conservation condition of cellulose nitrate and acetate in heritage collections: quantifying the degree of substitution by infrared spectroscopy by Nunes, Sofia, Ramacciotti, Francesca, Neves, Artur, Angelin, Eva Marisole, Ramos, Ana Maria, Roldão, Élia, Wallaszkovits, Nadja, Armijo, Alfonso Alejo, Melo, Maria João

“…Cellulose nitrate and acetate are materials at risk in heritage collections because it is not possible to predict the evolution of their conservation state…”
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Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis by Ramaswamy, Vijay, MD, Remke, Marc, MD, Bouffet, Eric, Prof, Faria, Claudia C, MD, Perreault, Sebastien, MD, Cho, Yoon-Jae, MD, Shih, David J, MSc, Luu, Betty, BSc, Dubuc, Adrian M, PhD, Northcott, Paul A, PhD, Schüller, Ulrich, MD, Gururangan, Sridharan, Prof, McLendon, Roger, Prof, Bigner, Darell, Prof, Fouladi, Maryam, Prof, Ligon, Keith L, MD, Pomeroy, Scott L, Prof, Dunn, Sandra, PhD, Triscott, Joanna, BSc, Jabado, Nada, MD, Fontebasso, Adam, BSc, Jones, David T W, PhD, Kool, Marcel, PhD, Karajannis, Matthias A, MD, Gardner, Sharon L, MD, Zagzag, David, Prof, Nunes, Sofia, MD, Pimentel, José, MD, Mora, Jaume, MD, Lipp, Eric, MD, Walter, Andrew W, MD, Ryzhova, Marina, MD, Zheludkova, Olga, MD, Kumirova, Ella, MD, Alshami, Jad, BSc, Croul, Sidney E, Prof, Rutka, James T, Prof, Hawkins, Cynthia, Prof, Tabori, Uri, MD, Codispoti, Kari-Elise T, MD, Packer, Roger J, Prof, Pfister, Stefan M, Prof, Korshunov, Andrey, Prof, Taylor, Michael D, Prof

“…Summary Background Recurrent medulloblastoma is a therapeutic challenge because it is almost always fatal. Studies have confirmed that medulloblastoma consists…”
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Decision making based on hybrid modeling approach applied to cellulose acetate based historical films conservation by Al Mohtar, Abeer, Pinto, Moisés L., Neves, Artur, Nunes, Sofia, Zappi, Daniele, Varani, Gabriele, Ramos, Ana Maria, Melo, Maria João, Wallaszkovits, Nadja, Lahoz Rodrigo, Juan Ignacio, Herlt, Kerstin, Lopes, João

“…Preserving culture heritage cellulose acetate-based historical films is a challenge due to the long-term instability of these complex materials and a lack of…”
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Perinatal outcomes in children born after fresh or frozen embryo transfer using donated oocytes by Rafael, Filipa, Robles, Guillermo Mollá, Navarro, Alfredo T, Garrido, Nicolas, Garcia-Velasco, Juan A, Bosch, Ernesto, Nunes, Sofia Gouveia, Soares, Sérgio Reis, Santos-Ribeiro, Samuel

“…Abstract STUDY QUESTION Do children born after vitrified–thawed embryo transfers (ETs) using donated oocytes have worse perinatal outcomes when compared with…”
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Spontaneous thrombosis of cerebral arteriovenous malformation post COVID-19 by Rodrigues, Sofia Grenho, Oliveira, Renato, Vilela, Pedro, Oliveira, Sofia Nunes

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Selumetinib for plexiform neurofibromas in neurofibromatosis type 1: a single-institution experience by Espírito Santo, Vera, Passos, João, Nzwalo, Hipólito, Carvalho, Inês, Santos, Filipa, Martins, Carmo, Salgado, Lucília, Silva, Conceição e, Vinhais, Sofia, Vilares, Miguel, Salgado, Duarte, Nunes, Sofia

“…Background Plexiform neurofibromas (PN) are the most frequent tumors associated with Neurofibromatosis type 1 (NF-1). PN can cause significant complications,…”
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Recycling the Interspecific Relations with Epithelial Cells: Bacteria and Cancer Metabolic Symbiosis by Nunes, Sofia C, Serpa, Jacinta

“…Several aspects of the human physiology are controlled by the microbiota that plays a key role in health and disease. In fact, microbial dysbiosis is…”
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Targeting Glutathione and Cystathionine β-Synthase in Ovarian Cancer Treatment by Selenium-Chrysin Polyurea Dendrimer Nanoformulation by Santos, Inês, Ramos, Cristiano, Mendes, Cindy, Sequeira, Catarina O, Tomé, Catarina S, Fernandes, Dalila G H, Mota, Pedro, Pires, Rita F, Urso, Donato, Hipólito, Ana, Antunes, Alexandra M M, Vicente, João B, Pereira, Sofia A, Bonifácio, Vasco D B, Nunes, Sofia C, Serpa, Jacinta

“…Ovarian cancer is the main cause of death from gynecological cancer, with its poor prognosis mainly related to late diagnosis and chemoresistance (acquired or…”
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ESHRE PGT Consortium and SIG Embryology good practice recommendations for polar body and embryo biopsy for PGT by Kokkali, Georgia, Coticchio, Giovanni, Bronet, Fernando, Celebi, Catherine, Cimadomo, Danilo, Goossens, Veerle, Liss, Joanna, Nunes, Sofia, Sfontouris, Ioannis, Vermeulen, Nathalie, Zakharova, Elena, De Rycke, Martine

“…Abstract The field of preimplantation genetic testing (PGT) is evolving fast, and best practice advice is essential for regulation and standardisation of…”
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Right or duty of information: A Habermasian perspective by Nunes, Sofia RT, Rego, Guilhermina, Nunes, Rui

“…Background: The theoretical framework of Jϋrgen Habermas suggests that effective communication requires competent participants with an objective attitude that…”
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BRAF V600E mutation and 9p21: CDKN2A/B and MTAP co-deletions - Markers in the clinical stratification of pediatric gliomas by Frazão, Laura, do Carmo Martins, Maria, Nunes, Vasco Moura, Pimentel, José, Faria, Claudia, Miguéns, José, Sagarribay, Amets, Matos, Mário, Salgado, Duarte, Nunes, Sofia, Mafra, Manuela, Roque, Lúcia

“…Genetic alterations in pediatric primary brain tumors can be used as diagnostic and prognostic markers and are the basis for the development of new target…”
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