Search Results - "NUMATA, Yukio"
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Plasma brain-derived neurotrophic factor levels predict the clinical outcome of depression treatment in a naturalistic study
Published in PloS one (27-06-2012)“…Remission is the primary goal of treatment for major depressive disorder (MDD). However, some patients do not respond to treatment. The main purpose of this…”
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The noradrenaline metabolite MHPG is a candidate biomarker from the manic to the remission state in bipolar disorder I: a clinical naturalistic study
Published in PloS one (27-06-2014)“…Remission is the primary goal of treatment for bipolar disorder I (BDI). Metabolites of noradrenaline and dopamine, 3-methoxy-4-hydroxyphenylglycol (MHPG) and…”
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The noradrenaline metabolite MHPG is a candidate biomarker between the depressive, remission, and manic states in bipolar disorder I: two long-term naturalistic case reports
Published in Neuropsychiatric disease and treatment (01-01-2015)“…Treatment of the depressive and manic states in bipolar disorder I (BDI) is a challenge for psychiatrists. Despite the recognized importance of the switch…”
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Efficacy and Tolerability of Risperidone, Yokukansan, and Fluvoxamine for the Treatment of Behavioral and Psychological Symptoms of Dementia: A Blinded, Randomized Trial
Published in Journal of clinical psychopharmacology (01-10-2013)“…The descriptive term behavioral and psychological symptoms of dementia (BPSD) is used to cover a range of noncognitive disturbances including anxiety,…”
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Divergent effects of lithium and sodium valproate on brain-derived neurotrophic factor (BDNF) production in human astrocytoma cells at therapeutic concentrations
Published in Progress in neuro-psychopharmacology & biological psychiatry (01-10-2012)“…Mood stabilizers such as lithium (Li) or valproic acid (VPA) are used in the therapy of bipolar disorders, but the mechanisms by which these medicines work is…”
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Yokukansan improves behavioral and psychological symptoms of dementia by suppressing dopaminergic function
Published in Neuropsychiatric disease and treatment (01-01-2016)“…Although three drugs, risperidone, yokukansan, and fluvoxamine, have shown equal efficacy in treating behavioral and psychological symptoms of dementia (BPSD)…”
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Association of mu-opioid receptor gene polymorphism A118G with alcohol dependence in a Japanese population
Published in Neuropsychobiology (01-01-2006)“…Ethanol is considered to activate the brain reward system by increasing the release of an endogenous opioid receptor ligand, beta-endorphin. The polymorphism…”
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