Search Results - "NUCLEAR MEDICINE AND BIOLOGY"

Consensus nomenclature rules for radiopharmaceutical chemistry — Setting the record straight by Coenen, Heinz H., Gee, Antony D., Adam, Michael, Antoni, Gunnar, Cutler, Cathy S., Fujibayashi, Yasuhisa, Jeong, Jae Min, Mach, Robert H., Mindt, Thomas L., Pike, Victor W., Windhorst, Albert D.

“…Over recent years, within the community of radiopharmaceutical sciences, there has been an increased incidence of incorrect usage of established scientific…”
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The salivary glands as a dose limiting organ of PSMA- targeted radionuclide therapy: A review of the lessons learnt so far by Heynickx, Nathalie, Herrmann, Ken, Vermeulen, Koen, Baatout, Sarah, Aerts, An

“…At present, prostate cancer remains the second most occurring cancer in men, in Europe. Treatment efficacy for therapy of advanced metastatic disease, and…”
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Potent candidates for Targeted Auger Therapy: Production and radiochemical considerations by Filosofov, Dmitry, Kurakina, Elena, Radchenko, Valery

“…Targeted Auger Therapy represents great potential for the therapy of diseases which require a high degree of selectivity on the cellular level (e.g. for…”
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Nuclear data for production and medical application of radionuclides: Present status and future needs by Qaim, Syed M

“…Abstract Introduction The significance of nuclear data in the choice and medical application of a radionuclide is considered: the decay data determine its…”
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On the consensus nomenclature rules for radiopharmaceutical chemistry – Reconsideration of radiochemical conversion by Herth, Matthias M., Ametamey, Simon, Antuganov, Dmitrii, Bauman, Andreas, Berndt, Mathias, Brooks, Allen F., Bormans, Guy, Choe, Yearn Seong, Gillings, Nic, Häfeli, Urs O., James, Michelle L., Kopka, Klaus, Kramer, Vasko, Krasikova, Raisa, Madsen, Jacob, Mu, Linjing, Neumaier, Bernd, Piel, Markus, Rösch, Frank, Ross, Tobias, Schibli, Roger, Scott, Peter J.H., Shalgunov, Vladimir, Vasdev, Neil, Wadsak, Wolfgang, Zeglis, Brian M.

“…Radiochemical conversion is an important term to be included in the “Consensus nomenclature rules for radiopharmaceutical chemistry”. Radiochemical conversion…”
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Production, purification and availability of 211 At: Near term steps towards global access by Feng, Yutian, Zalutsky, Michael R

“…The promising characteristics of the 7.2-h radiohalogen At have long been recognized; including having chemical properties suitable for labeling targeting…”
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Overcoming nephrotoxicity in peptide receptor radionuclide therapy using [177Lu]Lu-DOTA-TATE for the treatment of neuroendocrine tumours by Geenen, Lorain, Nonnekens, Julie, Konijnenberg, Mark, Baatout, Sarah, De Jong, Marion, Aerts, An

“…Peptide receptor radionuclide therapy (PRRT) is used for the treatment of patients with unresectable or metastasized somatostatin receptor type 2…”
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The quest for improving the management of breast cancer by functional imaging: The discovery and development of 16α-[18F]fluoroestradiol (FES), a PET radiotracer for the estrogen receptor, a historical review by Katzenellenbogen, John A.

“…16α-[18F]Fluoroestradiol (FES), a PET radiotracer for the estrogen receptor (ER) in breast cancer, was the first receptor-targeted PET radiotracer for oncology…”
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Gold nanoparticles meet medical radionuclides by Daems, Noami, Michiels, Carine, Lucas, Stéphane, Baatout, Sarah, Aerts, An

“…Thanks to their unique optical and physicochemical properties, gold nanoparticles have gained increased interest as radiosensitizing, photothermal therapy and…”
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Alpha emitting nuclides for targeted therapy by Hatcher-Lamarre, Jasmine L., Sanders, Vanessa A., Rahman, Mohammed, Cutler, Cathy S., Francesconi, Lynn C.

“…Targeted alpha therapy (TAT) is an area of research with rapidly increasing importance as the emitted alpha particle has a significant effect on inducing…”
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Astatine-211 labeled anti-HER2 5F7 single domain antibody fragment conjugates: radiolabeling and preliminary evaluation by Choi, Jaeyeon, Vaidyanathan, Ganesan, Koumarianou, Eftychia, Kang, Choong Mo, Zalutsky, Michael R.

“…Derived from heavy chain only camelid antibodies, ~15-kDa single-domain antibody fragments (sdAbs) are an attractive platform for developing molecularly…”
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In vivo tracking of [89Zr]Zr-labeled engineered extracellular vesicles by PET reveals organ-specific biodistribution based upon the route of administration by Patel, Shil, Schmidt, Karl F., Farhoud, Mohammed, Zi, Tong, Jang, Su Chul, Dooley, Kevin, Kentala, Dustin, Dobson, Howard, Economides, Kyriakos, Williams, Douglas E.

“…Extracellular vesicles (EVs) have garnered increasing interest as delivery vehicles for multiple classes of therapeutics based on their role as mediators in an…”
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Standardized methods for the production of high specific-activity zirconium-89 by Holland, Jason P, Sheh, Yiauchung, Lewis, Jason S

“…Abstract Zirconium-89 is an attractive metallo-radionuclide for use in immuno-PET due to favorable decay characteristics. Standardized methods for the routine…”
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Cyclotron production of (44)Sc: From bench to bedside by van der Meulen, Nicholas P, Bunka, Maruta, Domnanich, Katharina A, Müller, Cristina, Haller, Stephanie, Vermeulen, Christiaan, Türler, Andreas, Schibli, Roger

“…(44)Sc, a PET radionuclide, has promising decay characteristics (T1/2 = 3.97 h, Eβ(+)av = 632 keV) for nuclear imaging and is an attractive alternative to the…”
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LogP, a yesterday's value? by Vraka, Chrysoula, Nics, Lukas, Wagner, Karl-Heinz, Hacker, Marcus, Wadsak, Wolfgang, Mitterhauser, Markus

“…Abstract Introduction There is an increasing demand for high throughput methods at early stages of preclinical radioligand development, in order to predict…”
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Production, isolation, and shipment of clinically relevant quantities of astatine-211: A simple and efficient approach to increasing supply by McIntosh, Lauren A., Burns, Jonathan D., Tereshatov, Evgeny E., Muzzioli, Riccardo, Hagel, Kris, Jinadu, Noimat A., McCann, Laura A., Picayo, Gabriela A., Pisaneschi, Federica, Piwnica-Worms, David, Schultz, Steven J., Tabacaru, Gabriel C., Abbott, Austin, Green, Brooklyn, Hankins, Travis, Hannaman, Andrew, Harvey, Bryan, Lofton, Kylie, Rider, Robert, Sorensen, Maxwell, Tabacaru, Alexandra, Tobin, Zachary, Yennello, Sherry J.

“…The alpha emitter astatine-211 (211At) is a promising candidate for cancer treatment based on Targeted Alpha (α) Therapy (TAT). A small number of facilities,…”
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Evaluation of chelating agents based on pyridine-azacrown compounds H4PATA, PATAM, and H4PATPA for 68Ga and 177Lu by Shchukina, Anna A., Zubenko, Anastasia D., Tarasenko, Oksana V., Larenkov, Anton A., Bubenshchikov, Viktor B., Chernikova, Ekaterina Y., Fedorov, Yury V., Fedorova, Olga A.

“…In this article, we present the synthesis and characterization of three macrocyclic chelators, H4PATA, PATAM, and H4PATPA, based on a pyridine-azacrown…”
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Current trends in the use of O-(2-[18F]fluoroethyl)-L-tyrosine ([18F]FET) in neurooncology by Stegmayr, Carina, Stoffels, Gabriele, Filß, Christian, Heinzel, Alexander, Lohmann, Philipp, Willuweit, Antje, Ermert, Johannes, Coenen, Heinz H., Mottaghy, Felix M., Galldiks, Norbert, Langen, Karl-Josef

“…The diagnostic potential of PET using the amino acid analogue O-(2-[18F]fluoroethyl)-L-tyrosine ([18F]FET) in brain tumor diagnostics has been proven in many…”
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A radioiodinated rucaparib analogue as an Auger electron emitter for cancer therapy by Destro, Gianluca, Chen, Zijun, Chan, Chung Ying, Fraser, Claudia, Dias, Gemma, Mosley, Michael, Guibbal, Florian, Gouverneur, Veronique, Cornelissen, Bart

“…Radioligand therapy (RLT) is an expanding field that has shown great potential in the fight against cancer. Radionuclides that can be carried by selective…”
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A decade of ubiquicidin development for PET imaging of infection: A systematic review by Marjanovic-Painter, Biljana, Kleynhans, Janke, Zeevaart, Jan Rijn, Rohwer, Egmont, Ebenhan, Thomas

“…Ubiquicidin is a peptide fragment with selective binding to negatively charged bacterial cell membranes. Besides its earlier labelling with gamma emitting…”
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