Search Results - "NS, Fearnhead"
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Genetics of colorectal cancer: hereditary aspects and overview of colorectal tumorigenesis
Published in British medical bulletin (01-01-2002)“…Familial adenomatous polyposis and hereditary non-polyposis colorectal cancer are dominantly inherited conditions with 100% and 80% life-time risk of…”
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2
Pelvic Exenteration for Advanced Nonrectal Pelvic Malignancy
Published in Annals of surgery (01-11-2019)“…OBJECTIVE:To determine factors associated with outcomes following pelvic exenteration for advanced nonrectal pelvic malignancy. BACKGROUND:The PelvEx…”
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3
Empty pelvis syndrome: PelvEx Collaborative guideline proposal
Published in British journal of surgery (09-11-2023)Get full text
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4
Palliative pelvic exenteration: A systematic review of patient-centered outcomes
Published in European journal of surgical oncology (01-10-2019)“…Palliative pelvic exenteration (PPE) is a technically complex operation with high morbidity and mortality rates, considered in patients with limited life…”
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Simultaneous pelvic exenteration and liver resection for primary rectal cancer with synchronous liver metastases: results from the PelvEx Collaborative
Published in Colorectal disease (01-10-2020)“…Aim At presentation, 15–20% of patients with rectal cancer already have synchronous liver metastases. The aim of this study was to determine the surgical and…”
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6
Development of a core descriptor set for Crohn's anal fistula
Published in Colorectal disease (01-04-2023)“…Aim Crohn's anal fistula (CAF) is a complex condition, with no agreement on which patient characteristics should be routinely reported in studies. The aim of…”
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The impact of the COVID‐19 pandemic on the Management of Locally Advanced Primary/Recurrent Rectal Cancer
Published in British journal of surgery (01-10-2020)Get full text
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8
The ABC of APC
Published in Human molecular genetics (01-04-2001)“…Familial adenomatous polyposis (FAP) is an autosomal dominant inherited disease characterized by the presence of adenomatous polyps in the colon and rectum,…”
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Beating the empty pelvis syndrome: the PelvEx Collaborative core outcome set study protocol
Published in BMJ open (05-02-2024)“…IntroductionThe empty pelvis syndrome is a significant source of morbidity following pelvic exenteration surgery. It remains poorly defined with research in…”
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10
The global cost of pelvic exenteration: in‐hospital perioperative costs
Published in British journal of surgery (01-10-2020)Get full text
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11
Predicting outcomes of pelvic exenteration using machine learning
Published in Colorectal disease (01-12-2020)“…Aim We aim to compare machine learning with neural network performance in predicting R0 resection (R0), length of stay > 14 days (LOS), major complication…”
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Changing outcomes following pelvic exenteration for locally advanced and recurrent rectal cancer
Published in BJS open (01-08-2019)“…Background Pelvic exenteration for locally advanced rectal cancer (LARC) and locally recurrent rectal cancer (LRRC) is technically challenging but increasingly…”
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The colorectal surgeon's personality may influence the rectal anastomotic decision
Published in Colorectal disease (01-11-2018)“…Aim Colorectal surgeons regularly make the decision to anastomose, defunction or form an end colostomy when performing rectal surgery. This study aimed to…”
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14
Multiple Rare Variants in Different Genes Account for Multifactorial Inherited Susceptibility to Colorectal Adenomas
Published in Proceedings of the National Academy of Sciences - PNAS (09-11-2004)“…Clear-cut inherited Mendelian traits, such as familial adenomatous polyposis or hereditary nonpolyposis colorectal cancer, account for <4% of colorectal…”
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Perioperative management and anaesthetic considerations in pelvic exenterations using Delphi methodology: results from the PelvEx Collaborative
Published in BJS open (01-01-2021)“…The multidisciplinary perioperative and anaesthetic management of patients undergoing pelvic exenteration is essential for good surgical outcomes. No clear…”
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Induction chemotherapy followed by chemoradiotherapy versus chemoradiotherapy alone as neoadjuvant treatment for locally recurrent rectal cancer: study protocol of a multicentre, open-label, parallel-arms, randomized controlled study (PelvEx II)
Published in BJS open (2021)“…A resection with clear margins (R0 resection) is the most important prognostic factor in patients with locally recurrent rectal cancer (LRRC). However, this is…”
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Long-term follow-up of strictureplasty for Crohn's disease
Published in British journal of surgery (01-04-2006)“…Background: Strictureplasty is an effective means of alleviating obstructive Crohn's disease while conserving bowel length. The aim of this study was to…”
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18
Rare Variant Hypothesis for Multifactorial Inheritance: Susceptibility to Colorectal Adenomas as a Model
Published in Cell cycle (Georgetown, Tex.) (01-04-2005)“…The rare variant hypothesis postulates that genetic susceptibility to colorectal neoplasia within the general population is due to a number of low frequency…”
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Familial adenomatous polyposis and MYH
Published in The Lancet (British edition) (05-07-2003)“…[Julian Sampson] and colleagues now establish that adenomatous polyposis due to MYH mutation is an autosomal recessive disorder. They evaluated all available…”
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Clinical features and differential diagnosis of diverticular disease
Published in Baillière's best practice & research. Clinical gastroenterology (01-08-2002)“…Colonic diverticulosis occurs in the majority of Western populations with age, but only a small proportion of people experience symptoms. Diverticular disease…”
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