Search Results - "NOWOTNY, Peter J"
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Differential Patterns and Determinants of Cardiac Autonomic Nerve Dysfunction during Endotoxemia and Oral Fat Load in Humans
Published in PloS one (20-04-2015)“…The autonomic nervous system (ANS) plays an important role in regulating the metabolic homeostasis and controlling immune function. ANS alterations can be…”
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Mechanisms Underlying the Onset of Oral Lipid―Induced Skeletal Muscle Insulin Resistance in Humans
Published in Diabetes (New York, N.Y.) (01-07-2013)“…Several mechanisms, such as innate immune responses via Toll-like receptor-4, accumulation of diacylglycerols (DAG)/ceramides, and activation of protein kinase…”
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Effect of Low-Energy Diets Differing in Fiber, Red Meat, and Coffee Intake on Cardiac Autonomic Function in Obese Individuals With Type 2 Diabetes
Published in Diabetes care (01-09-2015)“…The autonomic nervous system (ANS) regulates both the cardiovascular system and energy balance and is disturbed in diabetes and obesity. The effect of…”
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Estimates of insulin sensitivity from the intravenous-glucose-modified-clamp test depend on suppression of lipolysis in type 2 diabetes: a randomised controlled trial
Published in Diabetologia (01-10-2014)“…Aims/hypothesis The combined IVGTT–hyperinsulinaemic–euglycaemic clamp (Botnia clamp) allows the assessment of insulin secretion and sensitivity in one…”
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Circulating triacylglycerols but not pancreatic fat associate with insulin secretion in healthy humans
Published in Metabolism, clinical and experimental (01-04-2018)“…Loss of adequate insulin secretion for the prevailing insulin resistance is critical for the development of type 2 diabetes and has been suggested to result…”
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Amino Acid and Fatty Acid Levels Affect Hepatic Phosphorus Metabolite Content in Metabolically Healthy Humans
Published in The journal of clinical endocrinology and metabolism (01-02-2018)“…Hepatic energy metabolism negatively relates to insulin resistance and liver fat content in patients with type 2 diabetes, but its role in metabolically…”
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Low-energy diets differing in fibre, red meat and coffee intake equally improve insulin sensitivity in type 2 diabetes: a randomised feasibility trial
Published in Diabetologia (01-02-2015)“…Aims/hypothesis Epidemiological studies have found that a diet high in fibre and coffee, but low in red meat, reduces the risk for type 2 diabetes. We tested…”
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Polar secretion of endothelin-1 by cultured endothelial cells
Published in The Journal of biological chemistry (15-08-1992)“…The aim of this study was to determine the permeability of endothelial monolayers for endothelin-1 and a possible directionality of the endothelin-1 secretion…”
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