Search Results - "NOWLIN, Dawn M"

Synthesis and SAR of N-benzoyl-L-biphenylalanine derivatives: Discovery of TR-14035, a dual α4β7/α4β1 integrin antagonist by SIRCAR, Ila, GUDMUNDSSON, Kristjan S, CONNELL, Samuel, GRIFFITH, Ronald C, LAZARIDES, Elias, MARTIN, Richard, LIANG, Jimmy, NOMURA, Sumihiro, JAYAKUMAR, Honnappa, TEEGARDEN, Bradley R, NOWLIN, Dawn M, CARDARELLI, Pina M, MAH, Jason R

Get full text

Inhibition of tyrosine kinases blocks adhesion-induced T-cell coactivation without interfering with T-cell adhesion to endothelial cell-surface ligands by Nowlin, Dawn M, Cardarelli, Pina M, Young, Lynn, Mah, Jason, Felts, Katherine A, Mastrangelo, Marian, Cobb, Ronald R

“…Integrin and cell adhesion molecule-regulated cellular adhesion plays an integral part in the recruitment and activation of lymphocytes. T-cell activation is a…”
Get full text

Brain capillary 46,000 dalton protein is cytoplasmic actin and is localized to endothelial plasma membrane by Pardridge, W M, Nowlin, D M, Choi, T B, Yang, J, Calaycay, J, Shively, J E

“…The most abundant protein of the brain capillary, which makes up the blood-brain barrier (BBB) in vivo, is a protein that migrates at a molecular weight of…”
Get more information

Initiation of human cytomegalovirus infection requires initial interaction with cell surface heparan sulfate by Compton, T, Nowlin, D M, Cooper, N R

“…In this report, we demonstrate that the initial event in human cytomegalovirus (HCMV) infection is attachment to extracellular heparan sulfate. Further, this…”
Get more information

Synthesis and SAR of N-benzoyl-L-biphenylalanine derivatives: discovery of TR-14035, a dual alpha(4)beta(7)/alpha(4)beta(1) integrin antagonist by Sircar, Ila, Gudmundsson, Kristjan S, Martin, Richard, Liang, Jimmy, Nomura, Sumihiro, Jayakumar, Honnappa, Teegarden, Bradley R, Nowlin, Dawn M, Cardarelli, Pina M, Mah, Jason R, Connell, Samuel, Griffith, Ronald C, Lazarides, Elias

“…alpha(4)beta(1) and alpha(4)beta(7) integrins are key regulators of physiologic and pathologic responses in inflammation and autoimmune disease. The…”
Get full text

Human cytomegalovirus penetrates host cells by pH-independent fusion at the cell surface by Compton, T, Nepomuceno, R R, Nowlin, D M

“…Biochemical, genetic, and morphological criteria were used to demonstrate that human cytomegalovirus penetrates permissive fibroblasts and nonpermissive…”
Get more information

A novel cyclic pentapeptide inhibits α4β1 and α5β1 integrin-mediated cell adhesion by NOWLIN, D. M, GORCSAN, F, MOSCINSKI, M, SHIU-LAN CHIANG, LOBL, T. J, CARDARELLI, P. M

Get full text

Synthesis and SAR of N-Benzoyl- l-Biphenylalanine Derivatives: Discovery of TR-14035, A Dual α 4β 7/α 4β 1 Integrin Antagonist by Sircar, Ila, Gudmundsson, Kristjan S, Martin, Richard, Liang, Jimmy, Nomura, Sumihiro, Jayakumar, Honnappa, Teegarden, Bradley R, Nowlin, Dawn M, Cardarelli, Pina M, Mah, Jason R, Connell, Samuel, Griffith, Ronald C, Lazarides, Elias

“…α 4β 1 and α 4β 7 integrins are key regulators of physiologic and pathologic responses in inflammation and autoimmune disease. The effectiveness of…”
Get full text

Cyclic RGD peptide inhibits α4β1 interaction with connecting segment 1 and vascular cell adhesion molecule by CARDARELLI, P. M, COBB, R. B, NOWLIN, D. M, SCHOLZ, W, GORCSAN, F, MOSCINSKI, M, YASUHARA, M, SHUI-LAN CHIANG, LOBL, T. J

Get full text

Expression of a human cytomegalovirus receptor correlates with infectibility of cells by NOWLIN, D. M, COOPER, N. R, COMPTON, T

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Adaptational ``Crosstalk'' and the Crucial Role of Methylation in Chemotactic Migration by Escherichia coli by Hazelbauer, Gerald L., Park, Chankyu, Nowlin, Dawn M.

“…We investigated roles of methylation in bacterial chemotaxis by characterizing a methyl-accepting transducer protein incapable of methylation because of amino…”
Get full text

Site-directed mutations altering methyl-accepting residues of a sensory transducer protein by Nowlin, D M, Bollinger, J, Hazelbauer, G L

“…The Trg protein is one of a family of transducer proteins that mediate chemotactic response in Escherichia coli. Transducers are methyl-accepting proteins that…”
Get more information

Differential binding of testosterone and estradiol to isoforms of sex hormone-binding globulin: selective alteration of estradiol binding in cirrhosis by Terasaki, T, Nowlin, D M, Pardridge, W M

“…The MCR of testosterone is decreased but the MCR of estradiol is unchanged in men with cirrhosis and elevated serum sex hormone-binding globulin (SHBG)…”
Get more information

Predominant low-molecular-weight proteins in isolated brain capillaries are histones by Pardridge, W M, Nowlin, D M, Calaycay, J, Shively, J E

“…Blood-brain barrier (BBB) function is endowed by the expression of unique proteins within the brain capillary endothelium. In the absence of knowing the…”
Get more information