Search Results - "NOVICK, S"
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Efficacy and safety of nilotinib in patients with KIT-mutated metastatic or inoperable melanoma: final results from the global, single-arm, phase II TEAM trial
Published in Annals of oncology (01-06-2017)“…The single-arm, phase II Tasigna Efficacy in Advanced Melanoma (TEAM) trial evaluated the KIT-selective tyrosine kinase inhibitor nilotinib in patients with…”
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Nilotinib in imatinib-resistant or imatinib-intolerant patients with chronic myeloid leukemia in chronic phase: 48-month follow-up results of a phase II study
Published in Leukemia (01-01-2013)“…Nilotinib (Tasigna) is a BCR–ABL1 tyrosine kinase inhibitor approved for the treatment of patients with Philadelphia chromosome-positive chronic myeloid…”
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The Structural Basis for Activation of the Rab Ypt1p by the TRAPP Membrane-Tethering Complexes
Published in Cell (27-06-2008)“…The multimeric membrane-tethering complexes TRAPPI and TRAPPII share seven subunits, of which four (Bet3p, Bet5p, Trs23p, and Trs31p) are minimally needed to…”
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Phase II study of nilotinib in patients with relapsed or refractory Philadelphia chromosome—positive acute lymphoblastic leukemia
Published in Leukemia (01-06-2013)Get full text
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Clinical and demographic features of atypical depression in outpatients with major depressive disorder : Preliminary findings from STARD
Published in The journal of clinical psychiatry (01-08-2005)“…To determine the frequency and demographic and clinical characteristics of depression with atypical features in a broadly representative sample of outpatients…”
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Current Themes in Microwave and Infrared Spectroscopy of Weakly Bound Complexes
Published in Chemical reviews (01-11-1994)“…High-resolution spectroscopy of weakly bound molecular complexes is discussed. The use of experimental and theoretical tools developed for studying weakly…”
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Arsenicals in hematologic cancers
Published in Seminars in oncology (01-10-2000)“…Arsenic trioxide (AT) has been the object of renewed interest as a therapeutic since studies in China in the late 1980s confirmed its efficacy in the treatment…”
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Enhancement of bismuth antibacterial activity with lipophilic thiol chelators
Published in Antimicrobial Agents and Chemotherapy (01-08-1997)“…Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
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Aux1p/Swa2p is required for cortical endoplasmic reticulum inheritance in Saccharomyces cerevisiae
Published in Molecular biology of the cell (01-09-2001)“…In the yeast Saccharomyces cerevisiae, the endoplasmic reticulum (ER) is found at the periphery of the cell and around the nucleus. The segregation of ER…”
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Differential activation of the immune system by virulent Streptococcus pneumoniae strains determines recovery or death of the host
Published in Clinical and experimental immunology (01-10-2003)“…SUMMARY Streptococcus pneumoniae infection may result in asymptomatic carriage, mucosal or invasive disease. We hypothesize that self‐limiting or fatal disease…”
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Virulence of Streptococcus pneumoniae may be determined independently of capsular polysaccharide
Published in FEMS microbiology letters (01-04-2004)“…Mice were inoculated intranasally with Streptococcus pneumoniae isolates of serotype 14 with different genetic backgrounds (14R, 14DW) and a capsular switch of…”
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Purification of TRAPP from Saccharomyces cerevisiae and identification of its mammalian counterpart
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Three-dimensional CT angiography of pancreatic carcinoma : Role in staging extent of disease
Published in American journal of roentgenology (1976) (1998)Get full text
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Effect of tegaserod in chronic constipation: a randomized, double-blind, controlled trial
Published in Clinical gastroenterology and hepatology (01-09-2004)“…Chronic constipation is a common gastrointestinal disorder. The aim of this study was to evaluate the efficacy, safety, and tolerability of tegaserod, a…”
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Complexometric Titration of Zinc: An Analytical Chemistry Laboratory Experiment
Published in Journal of chemical education (01-12-1997)“…Complexometric titrations with EDTA have traditionally been performed in undergraduate analytical chemistry courses to determine the calcium or magnesium…”
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How does zinc modify the common cold? Clinical observations and implications regarding mechanisms of action
Published in Medical hypotheses (01-03-1996)“…Clinical studies have shown that ionic zinc (Zn 2+) dissolved in the mouth shortened manifestations of the common cold significantly, by an unknown mechanism…”
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The highly conserved COPII coat complex sorts cargo from the endoplasmic reticulum and targets it to the golgi
Published in Cold Spring Harbor perspectives in biology (01-02-2013)“…Protein egress from the endoplasmic reticulum (ER) is driven by a conserved cytoplasmic coat complex called the COPII coat. The COPII coat complex contains an…”
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Zinc-induced suppression of inflammation in the respiratory tract, caused by infection with human rhinovirus and other irritants
Published in Medical hypotheses (01-10-1997)“…Free ionic zinc (Zn 2+) in saliva shortens duration and severity of common cold (CC) symptoms. It is proposed that Zn 2+ complexes with proteins of critical…”
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A Simple Method for Quantifying Functional Selectivity and Agonist Bias
Published in ACS chemical neuroscience (21-03-2012)“…Activation of seven-transmembrane (7TM) receptors by agonists does not always lead to uniform activation of all signaling pathways mediated by a given…”
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Bos1p, a membrane protein required for ER to Golgi transport in yeast, co‐purifies with the carrier vesicles and with Bet1p and the ER membrane
Published in The EMBO journal (01-10-1992)“…BOS1 and BET1 are required for transport from the ER to the Golgi complex in yeast and genetically interact with each other and a subset of the other genes,…”
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