Search Results - "NOVATI, Arianna"

Environmental stimulation in Huntington disease patients and animal models by Novati, Arianna, Nguyen, Huu Phuc, Schulze-Hentrich, Julia

“…While Huntington disease (HD) is caused solely by a polyglutamine expansion in the huntingtin gene, environmental factors can influence HD onset and…”
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Maternal separation decreases adult hippocampal cell proliferation and impairs cognitive performance but has little effect on stress sensitivity and anxiety in adult Wistar rats by Hulshof, Henriëtte J., Novati, Arianna, Sgoifo, Andrea, Luiten, Paul G.M., den Boer, Johan A., Meerlo, Peter

“…▶ Wistar rats seem rather resistant to the long-term effects of maternal separation. ▶ Maternal separation does not alter adult stress sensitivity and…”
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Sleep deprivation impairs spatial working memory and reduces hippocampal AMPA receptor phosphorylation by HAGEWOUD, ROELINA, HAVEKES, ROBBERT, NOVATI, ARIANNA, KEIJSER, JAN N., VAN DER ZEE, EDDY A., MEERLO, PETER

“…Summary Sleep is important for brain function and cognitive performance. Sleep deprivation (SD) may affect subsequent learning capacity and ability to form new…”
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Sexual behavior and testis morphology in the BACHD rat model by Novati, Arianna, Yu-Taeger, Libo, Gonzalez Menendez, Irene, Quintanilla Martinez, Leticia, Nguyen, Huu Phuc

“…Huntington disease (HD) is an autosomal dominant neurodegenerative disorder caused by a mutation in the huntingtin (HTT) gene, which results in brain…”
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Chronically Restricted Sleep Leads to Depression-Like Changes in Neurotransmitter Receptor Sensitivity and Neuroendocrine Stress Reactivity in Rats by NOVATI, Arianna, ROMAN, Viktor, CETIN, Timur, HAGEWOUD, Roelina, DEN BOER, Johan A, LUITEN, Paul G. M, MEERLO, Peter

“…Frequently disrupted and restricted sleep is a common problem for many people in our Western society. In the long run, insufficient sleep may have…”
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Intranasal Administration of Mesenchymal Stem Cells Ameliorates the Abnormal Dopamine Transmission System and Inflammatory Reaction in the R6/2 Mouse Model of Huntington Disease by Yu-Taeger, Libo, Stricker-Shaver, Janice, Arnold, Katrin, Bambynek-Dziuk, Patrycja, Novati, Arianna, Singer, Elisabeth, Lourhmati, Ali, Fabian, Claire, Magg, Janine, Riess, Olaf, Schwab, Matthias, Stolzing, Alexandra, Danielyan, Lusine, Nguyen, Hoa Huu Phuc

“…Intrastriatal administration of mesenchymal stem cells (MSCs) has shown beneficial effects in rodent models of Huntington disease (HD). However, the invasive…”
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BACHD rats expressing full-length mutant huntingtin exhibit differences in social behavior compared to wild-type littermates by Manfré, Giuseppe, Novati, Arianna, Faccini, Ilaria, Rossetti, Andrea C, Bosch, Kari, Molteni, Raffaella, Riva, Marco A, Van der Harst, Johanneke E, Nguyen, Huu Phuc, Homberg, Judith R

“…Huntington disease (HD) is a devastating inherited neurodegenerative disorder characterized by progressive motor, cognitive, and psychiatric symptoms without…”
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Evidences for Mutant Huntingtin Inducing Musculoskeletal and Brain Growth Impairments via Disturbing Testosterone Biosynthesis in Male Huntington Disease Animals by Yu-Taeger, Libo, Novati, Arianna, Weber, Jonasz Jeremiasz, Singer-Mikosch, Elisabeth, Pabst, Ann-Sophie, Cheng, Fubo, Saft, Carsten, Koenig, Jennifer, Ellrichmann, Gisa, Heikkinen, Taneli, Pouladi, Mahmoud A, Riess, Olaf, Nguyen, Huu Phuc

“…Body weight (BW) loss and reduced body mass index (BMI) are the most common peripheral alterations in Huntington disease (HD) and have been found in HD…”
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Structural and molecular myelination deficits occur prior to neuronal loss in the YAC128 and BACHD models of Huntington disease by Teo, Roy Tang Yi, Hong, Xin, Yu-Taeger, Libo, Huang, Yihui, Tan, Liang Juin, Xie, Yuanyun, To, Xuan Vinh, Guo, Ling, Rajendran, Reshmi, Novati, Arianna, Calaminus, Carsten, Riess, Olaf, Hayden, Michael R, Nguyen, Huu P, Chuang, Kai-Hsiang, Pouladi, Mahmoud A

“…White matter (WM) atrophy is a significant feature of Huntington disease (HD), although its aetiology and early pathological manifestations remain poorly…”
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A24 Mutant huntingtin impairs musculoskeletal and brain growth via disturbing testosterone biosynthesis in male huntington disease animals by Yu-Taeger, Libo, Novati, Arianna, Weber, Jonasz Jeremiasz, Singer-Mikosch, Elisabeth, Pabst, Ann-Sophie, Saft, Carsten, König, Jennifer, Ellrichmann, Gisa, Heikkinen, Taneli, Pouladi, Mahmoud A, Riess, Olaf, Nguyen, Huu Phuc

“…Body weight (BW) loss and reduced body mass index (BMI) are the most common peripheral alterations in Huntington disease (HD) and have been found in HD…”
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B05 Environment-driven influences and neuroprotection in the BACHD RAT model for huntington disease by Wassouf, Zinah, Hentrich, Thomas, Novati, Arianna, Riess, Olaf, Nguyen, Huu Phuc, Schulze-Hentrich, Julia M

“…BackgroundHuntington disease (HD) is a progressive neurodegenerative disorder caused by a mutation in the huntingtin (HTT) gene. Despite being a monogenic…”
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Validation of behavioral phenotypes in the BACHD rat model by Novati, Arianna, Manfré, Giuseppe, Flunkert, Stefanie, Van der Harst, Johanneke E., Homberg, Judith R., Wronski, Robert, Nguyen, Huu Phuc

“…•Validation of behavioral readouts is essential for preclinical research.•The reproducibility of BACHD rats’ phenotypes was assessed.•BACHD rats’ motor and…”
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B04 Environment-dependent modulation of striatal gene expression in the BACHD RAT model by Novati, Arianna, Hentrich, Thomas, Wassouf, Zinah, Weber, Jonasz, Yu-Taeger, Libo, Déglon, Nicole, Hoa Huu Phuc Nguyen, Schulze-Hentrich, Julia

“…BackgroundHuntington disease (HD) is an autosomal dominant neurodegenerative disorder caused by a polyglutamine expansion in exon 1 of the huntingtin (HTT)…”
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The BACHD rat model of Huntington disease shows slowed learning in a Go/No-Go-like test of visual discrimination by Clemensson, Erik Karl Håkan, Novati, Arianna, Clemensson, Laura Emily, Riess, Olaf, Nguyen, Huu Phuc

“…•BACHD rats performed a test of inhibitory control.•BACHD rats were slower than wild type rats at acquiring the task.•BACHD rats showed no deficit in…”
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Coping with Sleep Deprivation: Shifts in Regional Brain Activity and Learning Strategy by HAGEWOUD, Roelina, HAVEKES, Robbert, TIBA, Paula A, NOVATI, Arianna, HOGENELST, Koen, WEINREDER, Pim, VAN DER ZEE, Eddy A, MEERLO, Peter

“…dissociable cognitive strategies are used for place navigation. Spatial strategies rely on the hippocampus, an area important for flexible integration of novel…”
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Environment-dependent striatal gene expression in the BACHD rat model for Huntington disease by Novati, Arianna, Hentrich, Thomas, Wassouf, Zinah, Weber, Jonasz J., Yu-Taeger, Libo, Déglon, Nicole, Nguyen, Huu Phuc, Schulze-Hentrich, Julia M.

“…Huntington disease (HD) is an autosomal dominant neurodegenerative disorder caused by a mutation in the huntingtin ( HTT ) gene which results in progressive…”
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Chronic partial sleep deprivation reduces brain sensitivity to glutamate N-methyl-d-aspartate receptor-mediated neurotoxicity by NOVATI, ARIANNA, HULSHOF, HENRIËTTE J., GRANIC, IVICA, MEERLO, PETER

“…Summary It has been hypothesized that insufficient sleep may compromise neuronal function and contribute to neurodegenerative processes. While sleep loss by…”
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Despite higher glucocorticoid levels and stress responses in female rats, both sexes exhibit similar stress-induced changes in hippocampal neurogenesis by Hulshof, Henriëtte J., Novati, Arianna, Luiten, Paul G.M., den Boer, Johan A., Meerlo, Peter

“…► Female rats showed a higher HPA-axis activity and higher stress-induced CORT levels than males. ► The difference in HPA-regulation was independent of…”
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Sleep deprivation impairs spatial working memory and reduces hippocampal AMPA receptor phosphorylation: Sleep deprivation and working memory by HAGEWOUD, ROELINA, HAVEKES, ROBBERT, NOVATI, ARIANNA, KEIJSER, JAN N., VAN DER ZEE, EDDY A., MEERLO, PETER

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