Neuroblastomatous recurrence of ganglioglioma : Case report

Neuroblastomatous recurrence of ganglioglioma : Case report

This case is believed to be the first reported recurrent intracranial ganglioglioma with purely neuroblastomatous malignant transformation. A complete macroscopic resection of a right frontal lobe tumor in an 18-year-old woman revealed differentiated ganglioglioma. Seven years later a large, well-de...

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Bibliographic Details
Published in:Journal of neurosurgery Vol. 93; no. 4; pp. 698 - 700
Main Authors: DAVID, Karoly M, DE SANCTIS, Stefano, LEWIS, Paul D, NOURY, Ana M. S, EDWARDS, J. Martin
Format: Journal Article
Language:English
Published: Park Ridge, IL American Association of Neurological Surgeons 01-10-2000
Subjects:
Adult
Biological and medical sciences
Brain Neoplasms - pathology
Brain Neoplasms - surgery
Cell Transformation, Neoplastic
Female
Ganglioglioma - pathology
Ganglioglioma - surgery
Humans
Magnetic Resonance Imaging
Medical sciences
Neoplasms, Second Primary - pathology
Neoplasms, Second Primary - surgery
Neuroblastoma - pathology
Neuroblastoma - surgery
Neurology
Tomography, X-Ray Computed
Tumors of the nervous system. Phacomatoses
Human
Intracranial
Nervous system diseases
Relapse
Malignant tumor
Neuroblastoma
Cerebral disorder
Case study
Ganglioglioma
Central nervous system disease
Evolution
Benign neoplasm
Autonomic neuropathy
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Description
Summary:This case is believed to be the first reported recurrent intracranial ganglioglioma with purely neuroblastomatous malignant transformation. A complete macroscopic resection of a right frontal lobe tumor in an 18-year-old woman revealed differentiated ganglioglioma. Seven years later a large, well-demarcated recurrent tumor was again macroscopically totally resected in the same patient. Histological analysis showed malignant transformation in only the neuronal component of the original tumor. A review of the literature on recurrent gangliogliomas and their malignant transformation is included.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ObjectType-Report-1
ObjectType-Article-3
ISSN:0022-3085
1933-0693
DOI:10.3171/jns.2000.93.4.0698