Search Results - "NOTTER, R. H"

Surface activity of a synthetic lung surfactant containing a phospholipase-resistant phosphonolipid analog of dipalmitoyl phosphatidylcholine by Wang, Z, Schwan, A L, Lairson, L L, O'Donnell, J S, Byrne, G F, Foye, A, Holm, B A, Notter, R H

“…Surface activity and sensitivity to inhibition from phospholipase A2 (PLA2), lysophosphatidylcholine (LPC), and serum albumin were studied for a synthetic…”
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Surfactant Therapy for Acute Lung Injury and Acute Respiratory Distress Syndrome by Raghavendran, Krishnan, MD, Willson, D., MD, Notter, R.H., MD, PhD

“…This article examines exogenous lung surfactant replacement therapy and its usefulness in mitigating clinical acute lung injury (ALI) and the acute respiratory…”
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Additivity of protein and nonprotein inhibitors of lung surfactant activity by ZHENGDONG WANG, NOTTER, R. H

“…This study examined the degree of additivity of several physiologically relevant protein and nonprotein inhibitors in impairing the surface activity of whole…”
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Content-dependent activity of lung surfactant protein B in mixtures with lipids by Wang, Z, Baatz, J E, Holm, B A, Notter, R H

“…The content-dependent activity of surfactant protein (SP)-B was studied in mixtures with dipalmitoyl phosphatidylcholine (DPPC), synthetic lipids (SL), and…”
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Multiple mechanisms of lung surfactant inhibition by HOLM, B. A, ZHENGDONG WANG, NOTTER, R. H

“…We studied the mechanisms by which C16:0 lysophosphatidylcholine (LPC) and albumin inhibit the surface activity of calf lung surfactant extract (CLSE) by using…”
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Acid aspiration increases sensitivity to increased ambient oxygen concentrations by Knight, P R, Kurek, C, Davidson, B A, Nader, N D, Patel, A, Sokolowski, J, Notter, R H, Holm, B A

“…Previously we have demonstrated that prolonged exposure to 100% ambient oxygen leads to a marked loss in functional lung volume and lung compliance, hypoxemia,…”
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Pulmonary Inflammation Disrupts Surfactant Function during Pneumocystis carinii Pneumonia by Wright, T W, Notter, R H, Wang, Z, Harmsen, A G, Gigliotti, F

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Surfactant treatment of full-term newborns with respiratory failure by AUTEN, R. L, NOTTER, R. H, KENDIG, J. W, DAVIS, J. M, SHAPIRO, D. L

“…Surfactant inactivation has been shown to be a significant factor in animal models of lung injury and may also be important in some forms of respiratory…”
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Separation of subfractions of the hydrophobic components of calf lung surfactant by Hall, S B, Wang, Z, Notter, R H

“…This study reports the biochemical separation of the hydrophobic constituents of calf lung surfactant into separate fractions from which specific components…”
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Effects of hemoglobin and cell membrane lipids on pulmonary surfactant activity by Holm, B A, Notter, R H

“…These experiments characterize the effects of hemoglobin and erythrocyte membrane lipids on the dynamic surface activity and adsorption facility of whole lung…”
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A biophysical mechanism by which plasma proteins inhibit lung surfactant activity by Holm, B A, Enhorning, G, Notter, R H

“…These in vitro experiments study a potential mechanism by which plasma proteins, found in the alveoli during pulmonary edema and hemorrhage, may act to inhibit…”
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Dynamic surface activity of films of lung surfactant phospholipids, hydrophobic proteins, and neutral lipids by Wang, Z, Hall, S B, Notter, R H

“…Surface pressure-area (pi-A) isotherms during dynamic cycling were measured for films of dipalmitoyl phosphatidylcholine (DPPC) and column-separated fractions…”
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Differential activity and lack of synergy of lung surfactant proteins SP-B and SP-C in interactions with phospholipids by Wang, Z, Gurel, O, Baatz, J E, Notter, R H

“…This study shows that the hydrophobic lung surfactant proteins (SP)-B and SP-C are not synergistic in enhancing functionally relevant surface behaviors in…”
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Approximations in the measurement of surface tension on the oscillating bubble surfactometer by Hall, S B, Bermel, M S, Ko, Y T, Palmer, H J, Enhorning, G, Notter, R H

“…This paper examines two factors, shape deformation and surface viscosity, that affect measurements of surface tension of lung surfactants with the oscillating…”
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Inhibition of pulmonary surfactant by oleic acid: mechanisms and characteristics by Hall, S B, Lu, R Z, Venkitaraman, A R, Hyde, R W, Notter, R H

“…The inhibitory effects of oleic acid (OA) on the surface activity of pulmonary surfactant were characterized by use of the oscillating bubble surfactometer,…”
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Double-blind clinical trial of calf lung surfactant extract for the prevention of hyaline membrane disease in extremely premature infants by KWONG, M. S, EGAN, E. A, NOTTER, R. H, SHAPIRO, D. L

“…A prospective, double-blind, controlled trial was conducted to determine whether instillation of an exogenous surfactant into the lungs before the first breath…”
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Roles of different hydrophobic constituents in the adsorption of pulmonary surfactant by Wang, Z, Hall, S B, Notter, R H

“…Surface tension-time adsorption isotherms were measured at 37 degrees C for calf lung surfactant extract (CLSE) and subfractions of its constituents: the…”
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Changes in surfactant protein gene expression in a neonatal rabbit model of hyperoxia-induced fibrosis by D'Angio, C T, Finkelstein, J N, Lomonaco, M B, Paxhia, A, Wright, S A, Baggs, R B, Notter, R H, Ryan, R M

“…Lung injuries, including bronchopulmonary dysplasia, alter the surfactant system. We developed a newborn rabbit model of acute, followed by chronic, hyperoxic…”
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Comparison of Two Strategies for Surfactant Prophylaxis in Very Premature Infants: A Multicenter Randomized Trial by Kendig, James W, Ryan, Rita M, Sinkin, Robert A, Maniscalco, William M, Notter, Robert H, Guillet, Ronnie, Cox, Christopher, Dweck, Harry S, Horgan, Michael J, Reubens, Linda J, Risemberg, Herman, Phelps, Dale L

“…Previous trials of surfactant therapy in premature infants have demonstrated a survival advantage associated with prophylactic therapy as an immediate bolus,…”
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Content of dipalmitoyl phosphatidylcholine in lung surfactant : Ramifications for surface activity by HOLM, B. A, WANG, Z, EGAN, E. A, NOTTER, R. H

“…The content of dipalmitoyl phophatidylcholine (DPPC) in the phosphatidylcholine (PC) fraction of calf lung surfactant extract (CLSE) is measured by gas…”
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