Search Results - "NOSKE, Aurelia"

Multispectral Optoacoustic Tomography (MSOT) of Human Breast Cancer by Diot, Gael, Metz, Stephan, Noske, Aurelia, Liapis, Evangelos, Schroeder, Barbara, Ovsepian, Saak V, Meier, Reinhard, Rummeny, Ernst, Ntziachristos, Vasilis

“…In a pilot study, we introduce fast handheld multispectral optoacoustic tomography (MSOT) of the breast at 28 wavelengths, aiming to identify high-resolution…”
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Impact of Modified 2013 ASCO/CAP Guidelines on HER2 Testing in Breast Cancer. One Year Experience by Varga, Zsuzsanna, Noske, Aurelia

“…The latest guidelines of the American Society of Clinical Oncology/College of American Pathologists (ASCO/CAP) to test Human Epidermal Growth Factor Receptor 2…”
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Slug and Sox9 Cooperatively Determine the Mammary Stem Cell State by Guo, Wenjun, Keckesova, Zuzana, Donaher, Joana Liu, Shibue, Tsukasa, Tischler, Verena, Reinhardt, Ferenc, Itzkovitz, Shalev, Noske, Aurelia, Zürrer-Härdi, Ursina, Bell, George, Tam, Wai Leong, Mani, Sendurai A., van Oudenaarden, Alexander, Weinberg, Robert A.

“…Regulatory networks orchestrated by key transcription factors (TFs) have been proposed to play a central role in the determination of stem cell states…”
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Tumor-Associated Lymphocytes As an Independent Predictor of Response to Neoadjuvant Chemotherapy in Breast Cancer by DENKERT, Carsten, LOIBL, Sibylle, VON TÖRNE, Christian, WEICHERT, Wilko, ENGELS, Knut, SOLBACH, Christine, SCHRADER, Iris, DIETEL, Manfred, VON MINCKWITZ, Gunter, NOSKE, Aurelia, ROLLER, Marc, MARIA MÜLLER, Berit, KOMOR, Martina, BUDCZIES, Jan, DARB-ESFAHANI, Silvia, KRONENWETT, Ralf, HANUSCH, Claus

“…PURPOSE Preclinical data suggest a contribution of the immune system to chemotherapy response. In this study, we investigated the prespecified hypothesis that…”
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Prognostic significance of POLE proofreading mutations in endometrial cancer by Church, David N, Stelloo, Ellen, Nout, Remi A, Valtcheva, Nadejda, Depreeuw, Jeroen, ter Haar, Natalja, Noske, Aurelia, Amant, Frederic, Tomlinson, Ian P M, Wild, Peter J, Lambrechts, Diether, Jürgenliemk-Schulz, Ina M, Jobsen, Jan J, Smit, Vincent T H B M, Creutzberg, Carien L, Bosse, Tjalling

“…Current risk stratification in endometrial cancer (EC) results in frequent over- and underuse of adjuvant therapy, and may be improved by novel biomarkers. We…”
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Metabolite profiling of human colon carcinoma--deregulation of TCA cycle and amino acid turnover by Denkert, Carsten, Budczies, Jan, Weichert, Wilko, Wohlgemuth, Gert, Scholz, Martin, Kind, Tobias, Niesporek, Silvia, Noske, Aurelia, Buckendahl, Anna, Dietel, Manfred, Fiehn, Oliver

“…Apart from genetic alterations, development and progression of colorectal cancer has been linked to influences from nutritional intake, hyperalimentation, and…”
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ARID1A mutations and PI3K/AKT pathway alterations in endometriosis and endometriosis-associated ovarian carcinomas by Samartzis, Eleftherios P, Noske, Aurelia, Dedes, Konstantin J, Fink, Daniel, Imesch, Patrick

“…Endometriosis is a common gynecological disease affecting 6%-10% of women of reproductive age and is characterized by the presence of endometrial-like tissue…”
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Class I Histone Deacetylase Expression Has Independent Prognostic Impact in Human Colorectal Cancer: Specific Role of Class I Histone Deacetylases In vitro and In vivo by Weichert, Wilko, Röske, Annika, Niesporek, Silvia, Noske, Aurelia, Buckendahl, Ann-Christin, Dietel, Manfred, Gekeler, Volker, Boehm, Markus, Beckers, Thomas, Denkert, Carsten

“…Purpose: Recently, several studies reported a strong functional link between histone deacetylases (HDAC) and the development of tumors of the large intestine…”
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How reliable is Ki-67 immunohistochemistry in grade 2 breast carcinomas? A QA study of the Swiss Working Group of Breast- and Gynecopathologists by Varga, Zsuzsanna, Diebold, Joachim, Dommann-Scherrer, Corina, Frick, Harald, Kaup, Daniela, Noske, Aurelia, Obermann, Ellen, Ohlschlegel, Christian, Padberg, Barbara, Rakozy, Christiane, Sancho Oliver, Sara, Schobinger-Clement, Sylviane, Schreiber-Facklam, Heide, Singer, Gad, Tapia, Coya, Wagner, Urs, Mastropasqua, Mauro G, Viale, Giuseppe, Lehr, Hans-Anton

“…Adjuvant chemotherapy decisions in breast cancer are increasingly based on the pathologist's assessment of tumor proliferation. The Swiss Working Group of…”
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The immunologic tumor microenvironment in endometrioid endometrial cancer in the morphomolecular context: mutual correlations and prognostic impact depending on molecular alterations by Willvonseder, Barbara, Stögbauer, Fabian, Steiger, Katja, Jesinghaus, Moritz, Kuhn, Peer-Hendrik, Brambs, Christine, Engel, Jutta, Bronger, Holger, Schmidt, Georg Philipp, Haller, Bernhard, Weichert, Wilko, Keller, Gisela, Noske, Aurelia, Pfarr, Nicole, Boxberg, Melanie

“…Objective POLE-mutant, microsatellite-instable (MSI), p53-mutant and non-specific molecular profile (NSMP) are TCGA-defined molecular subgroups of endometrial…”
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Interassay and interobserver comparability study of four programmed death-ligand 1 (PD-L1) immunohistochemistry assays in triple-negative breast cancer by Noske, Aurelia, Wagner, Daniel-Christoph, Schwamborn, Kristina, Foersch, Sebastian, Steiger, Katja, Kiechle, Marion, Oettler, Dirk, Karapetyan, Siranush, Hapfelmeier, Alexander, Roth, Wilfried, Weichert, Wilko

“…Different immunohistochemical programmed death-ligand 1 (PD-L1) assays and scorings have been reported to yield variable results in triple-negative breast…”
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Effect of MRE11 loss on PARP-inhibitor sensitivity in endometrial cancer in vitro by Koppensteiner, Romana, Samartzis, Eleftherios P, Noske, Aurelia, von Teichman, Adriana, Dedes, Ioannis, Gwerder, Myriam, Imesch, Patrick, Ikenberg, Kristian, Moch, Holger, Fink, Daniel, Stucki, Manuel, Dedes, Konstantin J

“…To evaluate the frequency of MRE11/RAD50/NBS1 (MRN)-complex loss of protein expression in endometrial cancers (EC) and to determine whether loss of MRE11…”
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Expression of the nuclear export protein chromosomal region maintenance/exportin 1/Xpo1 is a prognostic factor in human ovarian cancer by Noske, Aurelia, Weichert, Wilko, Niesporek, Silvia, Röske, Annika, Buckendahl, Ann‐Christin, Koch, Ines, Sehouli, Jalid, Dietel, Manfred, Denkert, Carsten

“…BACKGROUND The human nuclear export protein chromosomal region maintenance/exportin 1/Xpo1 (CRM1) mediates the nuclear export of proteins and messenger RNAs…”
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The G protein-coupled estrogen receptor (GPER) is expressed in two different subcellular localizations reflecting distinct tumor properties in breast cancer by Samartzis, Eleftherios P, Noske, Aurelia, Meisel, Alexander, Varga, Zsuzsanna, Fink, Daniel, Imesch, Patrick

“…The G protein-coupled estrogen receptor (GPER) is a novel estrogen receptor that mediates proliferative effects induced by estrogen but also by tamoxifen. The…”
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Comparison of EndoPredict and Oncotype DX test results in hormone receptor positive invasive breast cancer by Varga, Zsuzsanna, Sinn, Peter, Fritzsche, Florian, von Hochstetter, Arthur, Noske, Aurelia, Schraml, Peter, Tausch, Christoph, Trojan, Andreas, Moch, Holger

“…Several multigene expression-based tests offering prognostic and predictive information in hormone-receptor positive early breast cancer were established…”
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Risk stratification in luminal-type breast cancer: Comparison of Ki-67 with EndoPredict test results by Noske, Aurelia, Anders, Sophie-Isabelle, Ettl, Johannes, Hapfelmeier, Alexander, Steiger, Katja, Specht, Katja, Weichert, Wilko, Kiechle, Marion, Klein, Evelyn

“…Adjuvant chemotherapy decision in patients with hormone receptor positive, HER2 negative breast cancer (BC) is challenging. Ki-67 is widely used for adjuvant…”
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Characterization of Hormone Receptor and HER2 Status in Breast Cancer Using Mass Spectrometry Imaging by Gonçalves, Juliana Pereira Lopes, Bollwein, Christine, Noske, Aurelia, Jacob, Anne, Jank, Paul, Loibl, Sibylle, Nekljudova, Valentina, Fasching, Peter A, Karn, Thomas, Marmé, Frederik, Müller, Volkmar, Schem, Christian, Sinn, Bruno Valentin, Stickeler, Elmar, van Mackelenbergh, Marion, Schmitt, Wolfgang D, Denkert, Carsten, Weichert, Wilko, Schwamborn, Kristina

“…Immunohistochemical evaluation of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor-2 status stratify the different subtypes…”
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First prospective outcome data for the second-generation multigene test Endopredict in ER-positive/HER2-negative breast cancer by Ettl, Johannes, Anders, Sophie-Isabelle, Hapfelmeier, Alexander, Paepke, Stefan, Noske, Aurelia, Weichert, Wilko, Klein, Evelyn, Kiechle, Marion

“…Purpose Prospectively collected outcome data of patients (pts) whose adjuvant systemic therapy recommendation was based on the clinico-molecular test…”
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Loss of ARID1A/BAF250a-expression in endometriosis: a biomarker for risk of carcinogenic transformation? by Samartzis, Eleftherios P, Samartzis, Nicolas, Noske, Aurelia, Fedier, André, Caduff, Rosmarie, Dedes, Konstantin J, Fink, Daniel, Imesch, Patrick

“…Mutations of the tumor-suppressor gene ARID1A result in the loss of protein expression of the BRG-associated factor 250a (BAF250a), a large subunit of…”
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Expression of Class I Histone Deacetylases Indicates Poor Prognosis in Endometrioid Subtypes of Ovarian and Endometrial Carcinomas by Weichert, Wilko, Denkert, Carsten, Noske, Aurelia, Darb-Esfahani, Silvia, Dietel, Manfred, Kalloger, Steve E., Huntsman, David G., Köbel, Martin

“…Histone deacetylase (HDAC) inhibitors are an emerging class of targeted cancer therapeutics, and little is known about HDAC expression in gynecologic…”
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