Search Results - "NOSIKOV, Valery V"

The Role of Oxidative Stress in Diabetic Neuropathy: Generation of Free Radical Species in the Glycation Reaction and Gene Polymorphisms Encoding Antioxidant Enzymes to Genetic Susceptibility to Diabetic Neuropathy in Population of Type I Diabetic Patients by Babizhayev, Mark A., Strokov, Igor A., Nosikov, Valery V., Savel’yeva, Ekaterina L., Sitnikov, Vladimir F., Yegor E. Yegorov, Lankin, Vadim Z.

“…Diabetic neuropathy (DN) represents the main cause of morbidity and mortality among diabetic patients. Clinical data support the conclusion that the severity…”
Get full text

Association of polymorphic markers of genes FTO , KCNJ11, CDKAL1, SLC30A8, and CDKN2B with type 2 diabetes mellitus in the Russian population by Nikitin, Aleksey G, Potapov, Viktor Y, Brovkina, Olga I, Koksharova, Ekaterina O, Khodyrev, Dmitry S, Philippov, Yury I, Michurova, Marina S, Shamkhalova, Minara S, Vikulova, Olga K, Smetanina, Svetlana A, Suplotova, Lyudmila A, Kononenko, Irina V, Kalashnikov, Viktor Y, Smirnova, Olga M, Mayorov, Alexander Y, Nosikov, Valery V, Averyanov, Alexander V, Shestakova, Marina V

“…The association of type 2 diabetes mellitus (T2DM) with the and genes in the Russian population has not been well studied. In this study, we analysed the…”
Get full text

Asp299Gly and Thr399Ile Genotypes of the TLR4 Gene Are Associated With a Reduced Prevalence of Diabetic Neuropathy in Patients With Type 2 Diabetes by Gottfried Rudofsky, Jr, Peter Reismann, Steffen Witte, Per M. Humpert, Berend Isermann, Triantafyllos Chavakis, Jörg Tafel, Valery V. Nosikov, Andreas Hamann, Peter Nawroth, Angelika Bierhaus

“…Asp299Gly and Thr399Ile Genotypes of the TLR4 Gene Are Associated With a Reduced Prevalence of Diabetic Neuropathy in Patients With Type 2 Diabetes Gottfried…”
Get full text

Association of the CYBA, PPARGC1A, PPARG3, and PPARD gene variants with coronary artery disease and metabolic risk factors of coronary atherosclerosis in a Russian population by Nikitin, Alexey G., Chistiakov, Dimitry A., Minushkina, Larissa O., Zateyshchikov, Dmitry A., Nosikov, Valery V.

“…Abnormalities in lipid metabolism and enhanced oxidative stress are considered as major risk factors for coronary atherosclerosis. Functional genetic…”
Get full text

Adiponectin and adiponectin receptor gene variants in relation to type 2 diabetes and insulin resistance-related phenotypes by Potapov, Viktor A, Chistiakov, Dimitry A, Dubinina, Anna, Shamkhalova, Minara S, Shestakova, Marina V, Nosikov, Valery V

“…Alterations in adiponectin-mediated pathways are known to be associated with glucose intolerance, insulin resistance (IR), obesity, and type 2 diabetes (T2D)…”
Get full text

Leu54Phe and Val762Ala polymorphisms in the poly(ADP-ribose)polymerase-1 gene are associated with diabetic polyneuropathy in Russian type 1 diabetic patients by Nikitin, Alexey G, Chudakova, Dariya A, Strokov, Igor A, Bursa, Tamara R, Chistiakov, Dimitry A, Nosikov, Valery.V

“…Abstract Poly(ADP-ribose) polymerase-1 (PARP-1) is an ubiquitous DNA-binding protein involved in the cellular response to various genotoxic agents. Excessive…”
Get full text

A WFS1 haplotype consisting of the minor alleles of rs752854, rs10010131, and rs734312 shows a protective role against type 2 diabetes in Russian patients by Chistiakov, Dimitry A, Khodyrev, Dmitry S, Smetanina, Svetlana A, Bel'chikova, Larisa N, Suplotova, Lyudmila A, Nosikov, Valery V

“…Rare variants of the WFS1 gene encoding wolframin cause Wolfram syndrome, a monogenic disease associated with diabetes insipidus, diabetes mellitus, optic…”
Get full text

Polymorphisms in the Mn-SOD and EC-SOD genes and their relationship to diabetic neuropathy in type 1 diabetes mellitus by Chistyakov, D A, Savost'anov, K V, Zotova, E V, Nosikov, V V

“…Oxidative stress, resulting in a marked increase in the level of oxygen free radicals (OFR), has been implicated in the etiology of diabetic neuropathy (DN)…”
Get full text

An intuitive risk factors search algorithm: usage of the Bayesian network technique in personalized medicine by Maslennikov, Evgeny D., Sulimov, Alexey V., Savkin, Igor A., Evdokimova, Marina A., Zateyshchikov, Dmitry A., Nosikov, Valery V., Sulimov, Vladimir B.

“…The article focuses on the application of the Bayesian networks (BN) technique to problems of personalized medicine. The simple (intuitive) algorithm of BN…”
Get full text

The carriage of the type 1 diabetes-associated R262W variant of human LNK correlates with increased proliferation of peripheral blood monocytes in diabetic patients by Lavrikova, Elena Y, Nikitin, Alexey G, Kuraeva, Tamara L, Peterkova, Valentina A, Tsitlidze, Nina M, Chistiakov, Dimitry A, Nosikov, Valery V

“…Lavrikova EY, Nikitin AG, Kuraeva TL, Peterkova VA, Tsitlidze NM, Chistiakov DA, Nosikov VV. The carriage of the type 1 diabetes‐associated R262W variant of…”
Get full text

Advanced age, low left atrial appendage velocity, and Factor V promoter sequence variation as predictors of left atrial thrombosis in patients with nonvalvular atrial fibrillation by Zateyshchikov, Dmitry A., Brovkin, Alexey N., Chistiakov, Dimitry A., Nosikov, Valery V.

“…Atrial fibrillation (AF) renders individual patients at risk for development of an atrial thrombus. The aim of this study was to determine clinical and…”
Get full text

Studying progression from glucose intolerance to type 2 diabetes in obese children by Dubinina, Irina A, Chistiakov, Dimitry A, Eremina, Irina A, Brovkin, Alexei N, Zilberman, Lyubov I, Nikitin, Alexei G, Kuraeva, Tamara L, Nosikov, Valery V, Peterkova, Valentina A, Dedov, Ivan I

“…Abstract Aim Identification of metabolic and genetic factors capable to mediate progression from normal glucose tolerance (NGT) through impaired glucose…”
Get full text

The rs11705701 G>A polymorphism of IGF2BP2 is associated with IGF2BP2 mRNA and protein levels in the visceral adipose tissue - a link to type 2 diabetes susceptibility by Chistiakov, Dimitry A, Nikitin, Alexey G, Smetanina, Svetlana A, Bel'chikova, Larisa N, Suplotova, Lyudmila A, Shestakova, Marina V, Nosikov, Valery V

“…Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) regulates translation of IGF2, a growth factor that plays a key role in controlling fetal growth…”
Get full text

Association of CYP2D6 and ADRB1 genes with hypotensive and antichronotropic action of betaxolol in patients with arterial hypertension by Zateyshchikov, Dmitry A., Minushkina, Larissa O., Brovkin, Alexey N., Savel'eva, Ekaterina G., Zateyshchikova, Anna A., Manchaeva, Baira B., Nikitin, Alexey G., Sidorenko, Boris A., Nosikov, Valery V.

“…Betaxolol is a selective antagonist of β1‐adrenergic receptors. Personal response to the drug widely varies and depends on its properties and individual…”
Get full text

A splice variant of GNB3 and peripheral polyneuropathy in type 1 diabetes by Chistiakov, Dimitry A, Spitsina, Ekaterina V, Nikitin, Alexey G, Strokov, Igor A, Nosikov, Valery V

“…Abnormalities in G protein-mediated signal transduction could be involved in the pathogenesis of diabetic polyneuropathy (DPN). Here we test whether the GNB3…”
Get full text

A splice variant of GNB3 and peripheral polyneuropathy in type 1 diabetes by Chistiakov, Dimitry A, Spitsina, Ekaterina V, Nikitin, Alexey G, Strokov, Igor A, Nosikov, Valery V

“…Abnormalities in G protein-mediated signal transduction could be involved in the pathogenesis of diabetic polyneuropathy (DPN). Here we test whether the GNB3…”
Get full text

TCF7L2 rs12255372 and SLC30A8 rs13266634 confer susceptibility to type 2 diabetes in a Russian population by Potapov, Viktor A, Chistiakov, Dimitry A, Shamkhalova, Minara S, Shestakova, Marina V, Nosikov, Valery V

“…Abstract Aims Markers rs12255372 (G/T) of the transcription factor 7-like 2 (TCF7L2) and rs13266634 (R325W) of the solute carrier family 30 (zinc transporter)…”
Get full text

Replication of association between polymorphisms of the pancreatic ATP-sensitive potassium channel and susceptibility to type 2 diabetes in two Russian urban populations by Chistiakov Dimitry, Potapov Viktor, Khodirev Dmitry, Shamkhalova Minara, Shestakova Marina, Nosikov Valery

Get full text

Confirmation of a susceptibility locus for diabetic nephropathy on chromosome 3q23–q24 by association study in Russian type 1 diabetic patients by Chistiakov, Dimitry A., Savost’anov, Kirill V., Shestakova, Marina V., Chugunova, Lyudmila A., Samkhalova, Minara.Sh, Dedov, Ivan I., Nosikov, Valery V.

“…Family-based studies and segregation analyses suggest that inherited factors play a significant role in susceptibility to diabetic nephropathy (DN). Moczulski…”
Get full text

Further studies of genetic susceptibility to Graves' disease in a Russian population by Chistiakov, Dimitry A, Savost'anov, Kirill V, Turakulov, Rustam I, Petunina, Natal'ya, Balabolkin, Mikhail I, Nosikov, Valery V

“…Graves' disease (GD) is a polygenic autoimmune thyroid syndrome. Some of the genes implicated in its pathogenesis may encode thyroid-stimulating hormone…”
Get more information