Search Results - "NOSEWORTHY, PETER A."
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Urgent Guidance for Navigating and Circumventing the QTc-Prolonging and Torsadogenic Potential of Possible Pharmacotherapies for Coronavirus Disease 19 (COVID-19)
Published in Mayo Clinic proceedings (01-06-2020)“…As the coronavirus disease 19 (COVID-19) global pandemic rages across the globe, the race to prevent and treat this deadly disease has led to the “off-label”…”
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Non–Vitamin K Antagonist Oral Anticoagulant Dosing in Patients With Atrial Fibrillation and Renal Dysfunction
Published in Journal of the American College of Cardiology (13-06-2017)“…Abstract Background Dose reduction of non–vitamin K antagonist oral anticoagulants (NOACs) is indicated in patients with atrial fibrillation (AF) with renal…”
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Direct Comparison of Dabigatran, Rivaroxaban, and Apixaban for Effectiveness and Safety in Nonvalvular Atrial Fibrillation
Published in Chest (01-12-2016)“…Background The introduction of non-vitamin K antagonist oral anticoagulants (NOACs) has been a major advance for stroke prevention in atrial fibrillation (AF)…”
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4
Lifestyle and Risk Factor Modification for Reduction of Atrial Fibrillation: A Scientific Statement From the American Heart Association
Published in Circulation (New York, N.Y.) (21-04-2020)“…Atrial fibrillation (AF), the most common sustained cardiac arrhythmia, is associated with substantial morbidity, mortality, and healthcare use. Great strides…”
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Screening for cardiac contractile dysfunction using an artificial intelligence–enabled electrocardiogram
Published in Nature medicine (01-01-2019)“…Asymptomatic left ventricular dysfunction (ALVD) is present in 3–6% of the general population, is associated with reduced quality of life and longevity, and is…”
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Gastrointestinal Safety of Direct Oral Anticoagulants: A Large Population-Based Study
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2017)“…Background & Aims Direct oral anticoagulant (DOAC) agents increase the risk of gastrointestinal (GI) bleeding. We investigated which DOAC had the most…”
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Atrial Fibrillation Burden: Moving Beyond Atrial Fibrillation as a Binary Entity: A Scientific Statement From the American Heart Association
Published in Circulation (New York, N.Y.) (15-05-2018)“…Our understanding of the risk factors and complications of atrial fibrillation (AF) is based mostly on studies that have evaluated AF in a binary fashion…”
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Age and Sex Estimation Using Artificial Intelligence From Standard 12-Lead ECGs
Published in Circulation. Arrhythmia and electrophysiology (01-09-2019)“…BACKGROUND:Sex and age have long been known to affect the ECG. Several biologic variables and anatomic factors may contribute to sex and age-related…”
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Detection of Hypertrophic Cardiomyopathy Using a Convolutional Neural Network-Enabled Electrocardiogram
Published in Journal of the American College of Cardiology (25-02-2020)“…Hypertrophic cardiomyopathy (HCM) is an uncommon but important cause of sudden cardiac death. This study sought to develop an artificial intelligence approach…”
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Atrial fibrillation ablation in practice: assessing CABANA generalizability
Published in European heart journal (21-04-2019)“…The Catheter Ablation vs. Antiarrhythmic Drug Therapy for Atrial Fibrillation (CABANA) trial aimed to assess the impact of ablation on morbidity and mortality…”
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Electrocardiogram screening for aortic valve stenosis using artificial intelligence
Published in European heart journal (07-08-2021)“…Abstract Aims Early detection of aortic stenosis (AS) is becoming increasingly important with a better outcome after aortic valve replacement in asymptomatic…”
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Effectiveness and Safety of Dabigatran, Rivaroxaban, and Apixaban Versus Warfarin in Nonvalvular Atrial Fibrillation
Published in Journal of the American Heart Association (13-06-2016)“…Background The introduction of non–vitamin K antagonist oral anticoagulants has been a major advance for stroke prevention in atrial fibrillation; however,…”
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Artificial Intelligence–Enabled Assessment of the Heart Rate Corrected QT Interval Using a Mobile Electrocardiogram Device
Published in Circulation (New York, N.Y.) (30-03-2021)“…Heart rate-corrected QT interval (QTc) prolongation, whether secondary to drugs, genetics including congenital long QT syndrome, and/or systemic diseases…”
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Guidance for cardiac electrophysiology during the COVID-19 pandemic from the Heart Rhythm Society COVID-19 Task Force; Electrophysiology Section of the American College of Cardiology; and the Electrocardiography and Arrhythmias Committee of the Council on Clinical Cardiology, American Heart Association
Published in Heart rhythm (01-09-2020)“…Coronavirus disease 2019 (COVID-19) is a global pandemic that is wreaking havoc on the health and economy of much of human civilization. Electrophysiologists…”
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Typical, atypical, and asymptomatic presentations of new-onset atrial fibrillation in the community: Characteristics and prognostic implications
Published in Heart rhythm (01-07-2016)“…Background The prognostic significance of the clinical presentation of atrial fibrillation (AF) is poorly defined. Objective The purpose of this study was to…”
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Subclinical and Device-Detected Atrial Fibrillation: Pondering the Knowledge Gap: A Scientific Statement From the American Heart Association
Published in Circulation (New York, N.Y.) (17-12-2019)“…The widespread use of cardiac implantable electronic devices and wearable monitors has led to the detection of subclinical atrial fibrillation in a substantial…”
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Smart Wearables for Cardiac Monitoring-Real-World Use beyond Atrial Fibrillation
Published in Sensors (Basel, Switzerland) (05-04-2021)“…The possibilities and implementation of wearable cardiac monitoring beyond atrial fibrillation are increasing continuously. This review focuses on the…”
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Effect of Adherence to Oral Anticoagulants on Risk of Stroke and Major Bleeding Among Patients With Atrial Fibrillation
Published in Journal of the American Heart Association (23-02-2016)“…Background In comparison to warfarin, non–vitamin K antagonist oral anticoagulants (NOACs) have the advantages of ease of dosing, fewer drug interactions, and…”
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Prospective validation of a deep learning electrocardiogram algorithm for the detection of left ventricular systolic dysfunction
Published in Journal of cardiovascular electrophysiology (01-05-2019)“…Objectives We sought to validate a deep learning algorithm designed to predict an ejection fraction (EF) less than or equal to 35% based on the 12‐lead…”
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Meta-analysis of selective serotonin reuptake inhibitor-associated QTc prolongation
Published in The journal of clinical psychiatry (01-05-2014)“…To evaluate the association between selective serotonin reuptake inhibitors (SSRIs) and corrected QT interval (QTc) prolongation via meta-analysis of…”
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