Search Results - "NOSAKA, Tetsuya"

Eya2, a Target Activated by Plzf, Is Critical for PLZF-RARA-Induced Leukemogenesis by Ono, Ryoichi, Masuya, Masahiro, Ishii, Satomi, Katayama, Naoyuki, Nosaka, Tetsuya

“…PLZF is a transcription factor that confers aberrant self-renewal in leukemogenesis, and the PLZF-RARA fusion gene causes acute promyelocytic leukemia (APL)…”
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Genetic polymorphisms and vincristine-induced peripheral neuropathy in patients treated with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone therapy by Sawaki, Akihiko, Miyazaki, Kana, Yamaguchi, Motoko, Takeuchi, Toshifumi, Kobayashi, Kyoko, Imai, Hiroshi, Tawara, Isao, Ono, Ryoichi, Nosaka, Tetsuya, Katayama, Naoyuki

“…Vincristine (VCR)-induced peripheral neuropathy (VIPN) is a common and life-long toxicity in lymphoma patients receiving current standard chemotherapy. The…”
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Tet1 is not required for myeloid leukemogenesis by MLL-ENL in novel mouse models by Ono, Ryoichi, Masuya, Masahiro, Inoue, Naokazu, Shinmei, Makoto, Ishii, Satomi, Maegawa, Yuri, Maharjan, Bishnu Devi, Katayama, Naoyuki, Nosaka, Tetsuya

“…The Ten Eleven Translocation 1 (TET1) gene encodes an epigenetic modifying molecule that is involved in demethylation of 5-methylcytosine. In hematological…”
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Eya2 is critical for the E2A‑HLF‑mediated immortalization of mouse hematopoietic stem/progenitor cells by Maharjan, Bishnu Devi, Ono, Ryoichi, Nosaka, Tetsuya

“…The immunoglobulin enhancer‑binding factor/hepatic leukemia factor (E2A‑HLF) oncogenic fusion gene, generated by t(17;19)(q22;p13) translocation in childhood…”
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Nucleocytoplasmic shuttling of the human parainfluenza virus type 2 phosphoprotein by Ohtsuka, Junpei, Matsumoto, Yusuke, Ohta, Keisuke, Fukumura, Masayuki, Tsurudome, Masato, Nosaka, Tetsuya, Nishio, Machiko

“…Human parainfluenza virus type 2 phosphoprotein (P) is an essential component of viral polymerase. The P gene encodes both P and accessory V proteins by a…”
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Immunological association of inducible bronchus-associated lymphoid tissue organogenesis in Ag85B-rHPIV2 vaccine-induced anti-tuberculosis mucosal immune responses in mice by Nagatake, Takahiro, Suzuki, Hidehiko, Hirata, So-ichiro, Matsumoto, Naomi, Wada, Yasuko, Morimoto, Sakiko, Nasu, Ayaka, Shimojou, Michiko, Kawano, Mitsuo, Ogami, Kentaro, Tsujimura, Yusuke, Kuroda, Etsushi, Iijima, Norifumi, Hosomi, Koji, Ishii, Ken J, Nosaka, Tetsuya, Yasutomi, Yasuhiro, Kunisawa, Jun

“…Abstract We previously reported that Ag85B-expressing human parainfluenza type 2 virus (Ag85B-rHPIV2) was effective as a nasal vaccine against tuberculosis in…”
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The Hemagglutinin-Neuraminidase (HN) Head Domain and the Fusion (F) Protein Stalk Domain of the Parainfluenza Viruses Affect the Specificity of the HN-F Interaction by Tsurudome, Masato, Ohtsuka, Junpei, Ito, Morihiro, Nishio, Machiko, Nosaka, Tetsuya

“…Membrane fusion by the parainfluenza viruses is induced by virus-specific functional interaction between the attachment protein (HN) and the fusion (F)…”
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MYD88, CD79B, and CARD11 gene mutations in CD5‐positive diffuse large B‐cell lymphoma by Takeuchi, Toshifumi, Yamaguchi, Motoko, Kobayashi, Kyoko, Miyazaki, Kana, Tawara, Isao, Imai, Hiroshi, Ono, Ryoichi, Nosaka, Tetsuya, Tanaka, Kyosuke, Katayama, Naoyuki

“…BACKGROUND CD5‐positive (CD5+) diffuse large B‐cell lymphoma (DLBCL) is characterized by frequent central nervous system recurrence and a predominant activated…”
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AML1 mutations induced MDS and MDS/AML in a mouse BMT model by Watanabe-Okochi, Naoko, Kitaura, Jiro, Ono, Ryoichi, Harada, Hironori, Harada, Yuka, Komeno, Yukiko, Nakajima, Hideaki, Nosaka, Tetsuya, Inaba, Toshiya, Kitamura, Toshio

“…Myelodysplastic syndrome (MDS) is a hematopoietic stem-cell disorder characterized by trilineage dysplasia and susceptibility to acute myelogenous leukemia…”
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A versatile platform technology for recombinant vaccines using non-propagative human parainfluenza virus type 2 vector by Ohtsuka, Junpei, Fukumura, Masayuki, Furuyama, Wakako, Wang, Shujie, Hara, Kenichiro, Maeda, Mitsuyo, Tsurudome, Masato, Miyamoto, Hiroko, Kaito, Aika, Tsuda, Nobuyuki, Kataoka, Yosky, Mizoguchi, Akira, Takada, Ayato, Nosaka, Tetsuya

“…Ectopic protein with proper steric structure was efficiently loaded onto the envelope of the F gene-defective BC-PIV vector derived from human parainfluenza…”
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Restrictive IL-10 induction by an innocuous parainfluenza virus vector ameliorates nasal allergy by Yamanaka, Keiichi, MD, Nakanishi, Takehisa, MD, Isono, Kana, MS, Hasegawa, Chisami, MD, Inada, Hiroyasu, MD, Mizutani, Kento, MD, Matsushima, Yoshiaki, MD, Okada, Karin, MD, Mabuchi, Tomotaka, MD, Kondo, Makoto, MD, Yamagiwa, Akisa, MD, Kakeda, Masato, MD, Habe, Koji, MD, Nosaka, Tetsuya, MD, Gabazza, Esteban C., MD, Yamazaki, Hidetoshi, DDS, Mizutani, Hitoshi, MD, Kawano, Mitsuo, PhD

“…(ProQuest: ... denotes formulae and/or non US-ASCII text omitted; see image) To the Editor: IL-10 is a regulatory cytokine secreted during inflammatory…”
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Non-propagative human parainfluenza virus type 2 nasal vaccine robustly protects the upper and lower airways against SARS-CoV-2 by Ohtsuka, Junpei, Imai, Masaki, Fukumura, Masayuki, Maeda, Mitsuyo, Eguchi, Asami, Ono, Ryoichi, Maemura, Tadashi, Ito, Mutsumi, Yamayoshi, Seiya, Kataoka, Yosky, Kawaoka, Yoshihiro, Nosaka, Tetsuya

“…We developed an intranasal vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using the replication-incompetent human parainfluenza…”
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Bleomycin-Induced Pulmonary Fibrosis in Transgenic Mice Carrying the Human MUC5B rs35705950 Variant by Tharavecharak, Suphachai, Fujimoto, Hajime, Yasuma, Taro, D'Alessandro-Gabazza, Corina N, Toda, Masaaki, Tomaru, Atsushi, Saiki, Haruko, Uemura, Mei, Kogue, Yurie, Ito, Toshiyuki, Furuhashi, Kazuki, Okano, Tomohito, Takeshita, Atsuro, Nishihama, Kota, Ono, Ryoichi, Hataji, Osamu, Nosaka, Tetsuya, Kobayashi, Tetsu, Gabazza, Esteban C

“…Idiopathic pulmonary fibrosis (IPF) is a progressive, often fatal lung disease characterized by tissue scarring and declining lung function. The promoter…”
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Recombinant Ag85B vaccine by taking advantage of characteristics of human parainfluenza type 2 virus vector showed Mycobacteria-specific immune responses by intranasal immunization by Watanabe, Kenta, Matsubara, Akihiro, Kawano, Mitsuo, Mizuno, Satoru, Okamura, Tomotaka, Tsujimura, Yusuke, Inada, Hiroyasu, Nosaka, Tetsuya, Matsuo, Kazuhiro, Yasutomi, Yasuhiro

“…Highlights • We assessed the effectiveness of novel mucosal vaccine using recombinant human parainfluenza type 2 virus (rhPIV2) for TB (rhPIV2–Ag85B). •…”
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A Rac GTPase-Activating Protein, MgcRacGAP, Is a Nuclear Localizing Signal-Containing Nuclear Chaperone in the Activation of STAT Transcription Factors by Kawashima, Toshiyuki, Bao, Ying Chun, Minoshima, Yukinori, Nomura, Yasushi, Hatori, Tomonori, Hori, Tetsuya, Fukagawa, Tatsuo, Fukada, Toshiyuki, Takahashi, Noriko, Nosaka, Tetsuya, Inoue, Makoto, Sato, Tomohiro, Kukimoto-Niino, Mutsuko, Shirouzu, Mikako, Yokoyama, Shigeyuki, Kitamura, Toshio

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Rac1 and a GTPase-Activating Protein, MgcRacGAP, Are Required for Nuclear Translocation of STAT Transcription Factors by Toshiyuki Kawashima, Ying Chun Bao, Yasushi Nomura, Moon, Yuseok, Yukio Tonozuka, Yukinori Minoshima, Tomonori Hatori, Akiho Tsuchiya, Kiyono, Mari, Nosaka, Tetsuya, Hideaki Nakajima, Williams, David A., Kitamura, Toshio

“…STAT transcription factors are tyrosine phosphorylated upon cytokine stimulation and enter the nucleus to activate target genes. We show that Rac1 and a…”
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Recent advances in the model animals for hematopoietic tumors by Nosaka, Tetsuya

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Cv2, functioning as a pro-BMP factor via twisted gastrulation, is required for early development of nephron precursors by Ikeya, Makoto, Fukushima, Kumi, Kawada, Masako, Onishi, Sachiko, Furuta, Yasuhide, Yonemura, Shigenobu, Kitamura, Toshio, Nosaka, Tetsuya, Sasai, Yoshiki

“…The fine-tuning of BMP signals is critical for many aspects of complex organogenesis. In this report, we show that the augmentation of BMP signaling by a…”
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FLT3-ITD induces ara-C resistance in myeloid leukemic cells through the repression of the ENT1 expression by Jin, Guilan, Matsushita, Hiromichi, Asai, Satomi, Tsukamoto, Hideo, Ono, Ryoichi, Nosaka, Tetsuya, Yahata, Takashi, Takahashi, Shinichiro, Miyachi, Hayato

“…Fms-related tyrosine kinase 3-internal tandem duplications ( FLT3-ITD) are strongly associated with the refractory nature of acute myeloid leukemia (AML) by…”
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Phosphorylation by Aurora B Converts MgcRacGAP to a RhoGAP during Cytokinesis by Minoshima, Yukinori, Kawashima, Toshiyuki, Hirose, Koichi, Tonozuka, Yukio, Kawajiri, Aie, Bao, Ying Chun, Deng, Xingming, Tatsuka, Masaaki, Narumiya, Shuh, May, W.Stratford, Nosaka, Tetsuya, Semba, Kentaro, Inoue, Takafumi, Satoh, Takaya, Inagaki, Masaki, Kitamura, Toshio

“…Cell division is finely controlled by various molecules including small G proteins and kinases/phosphatases. Among these, Aurora B, RhoA, and the GAP MgcRacGAP…”
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