Search Results - "NORVAL, Mary"

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  1. 1

    The mechanisms and consequences of ultraviolet-induced immunosuppression by Norval, Mary

    “…Exposure to ultraviolet radiation (UVR) can result in immune suppression to antigens encountered within a few days of the irradiation. The process leading to…”
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  2. 2

    More Than Effects in Skin: Ultraviolet Radiation-Induced Changes in Immune Cells in Human Blood by Hart, Prue H, Norval, Mary

    Published in Frontiers in immunology (10-06-2021)
    “…Cells of the skin and circulation are in constant two-way communication. Following exposure of humans to sunlight or to phototherapy, there are alterations in…”
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  3. 3

    The challenges of UV-induced immunomodulation for children’s health by Norval, Mary

    “…Exposure to solar ultraviolet radiation (UVR) is recognised to have both beneficial and harmful effects on human health. With regard to immune responses, it…”
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  4. 4

    The Consequences of UV-Induced Immunosuppression for Human Health by Norval, Mary, Halliday, Gary M.

    Published in Photochemistry and photobiology (01-09-2011)
    “…Exposure to UV radiation can cause suppression of specific immune responses. The pathways leading to the down‐regulation are complex, starting from the…”
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    Urocanic Acid in the Skin: A Mixed Blessing? by Gibbs, Neil K., Norval, Mary

    Published in Journal of investigative dermatology (01-01-2011)
    “…Located in the stratum corneum, urocanic acid is a major epidermal chromophore for UVR. This simple molecule has attracted a great deal of research interest…”
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  7. 7

    Vitamin D and solar ultraviolet radiation in the risk and treatment of tuberculosis by Ralph, Anna P, Dr, Lucas, Robyn M, PhD, Norval, Mary, DSc

    Published in The Lancet infectious diseases (2013)
    “…Summary Improved understanding of the association between tuberculosis and vitamin D is needed to inform clinical practice. Vitamin D has both…”
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  8. 8

    Present and Future Impacts of Climate Change on Human Health in Sub-Saharan Africa by Wright, Caradee Yael, Norval, Mary

    Published in Atmosphere (01-12-2020)
    “…The impacts of climate change on human health and wellbeing in sub-Saharan Africa are projected to increase in the near future and are of considerable concern…”
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  9. 9

    Health Risks Associated With Excessive Exposure to Solar Ultraviolet Radiation Among Outdoor Workers in South Africa: An Overview by Wright, Caradee Y, Norval, Mary

    Published in Frontiers in public health (28-04-2021)
    “…Exposure of outdoor workers to high levels of solar ultraviolet radiation (UVR) poses significant, well-known health risks including skin cancer and eye…”
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  10. 10

    The Effect of Chronic Ultraviolet Radiation on the Human Immune System by Norval, Mary, McLoone, Pauline, Lesiak, Aleksandra, Narbutt, Joanna

    Published in Photochemistry and photobiology (01-01-2008)
    “…A single or a limited number of UVR exposures is recognized to suppress cell‐mediated immunity in human subjects. The complex pathway leading from the…”
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  11. 11

    Recent advances in urocanic acid photochemistry, photobiology and photoimmunology by Gibbs, Neil K, Tye, Joanne, Norval, Mary

    Published in Photochemical & photobiological sciences (01-06-2008)
    “…Urocanic acid (UCA), produced in the upper layers of mammalian skin, is a major absorber of ultraviolet radiation (UVR). Originally thought to be a 'natural…”
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  12. 12

    Photoimmunosuppression: a brief overview by Gibbs, Neil K., Norval, Mary

    “…Summary Exposure to ultraviolet radiation can lead to suppression of many adaptive immune responses, both to antigens encountered within a short period of the…”
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    The Incidence of Skin Cancer in Relation to Climate Change in South Africa by Wright, Caradee Y., Norval, Mary, Kapwata, Thandi, du Preez, David Jean, Wernecke, Bianca, Tod, Bianca M., Visser, Willem I.

    Published in Atmosphere (01-10-2019)
    “…Climate change is associated with shifts in global weather patterns, especially an increase in ambient temperature, and is deemed a formidable threat to human…”
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  15. 15

    Cis-urocanic acid, a sunlight-induced immunosuppressive factor, activates immune suppression via the 5-HT2A receptor by Walterscheid, Jeffrey P, Nghiem, Dat X, Kazimi, Nasser, Nutt, Leta K, McConkey, David J, Norval, Mary, Ullrich, Stephen E

    “…Exposure to UV radiation induces skin cancer and suppresses the immune response. To induce immune suppression, the electromagnetic energy of UV radiation must…”
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  16. 16

    Prostaglandin E2 imprints a long-lasting effect on dendritic cell progenitors in the bone marrow by Scott, Naomi M., Ng, Royce L. X., Gorman, Shelley, Norval, Mary, Waithman, Jason, Hart, Prue H.

    Published in Journal of leukocyte biology (01-02-2014)
    “…Prostaglandin E2 attenuates systemic immune responses by modulating dendritic cell progenitors in the bone marrow. Dendritic cells (DCs) that differentiate in…”
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  17. 17

    Effects of solar radiation on the human immune system by Norval, Mary

    “…On UV irradiation of the skin, a complex cascade of immunological changes results, initiated by cutaneous chromophores and ending in suppression of some local…”
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    Characterization of regulatory dendritic cells differentiated from the bone marrow of UV‐irradiated mice by Ng, Royce L. X., Scott, Naomi M., Bisley, Jackie L., Lambert, Misty J., Gorman, Shelley, Norval, Mary, Hart, Prue H.

    Published in Immunology (01-12-2013)
    “…Summary When antigen‐loaded dendritic cells (DCs) differentiated from the bone marrow (BM) of UV‐irradiated mice (UV‐BMDCs) were adoptively transferred into…”
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    cis-Urocanic Acid Initiates Gene Transcription in Primary Human Keratinocytes by Kaneko, Kazuyo, Smetana-Just, Ulrike, Matsui, Mary, Young, Antony R, John, Susan, Norval, Mary, Walker, Susan L

    Published in The Journal of immunology (1950) (01-07-2008)
    “…It is well established that solar UV radiation (UVR) suppresses cutaneous cell-mediated immunity in humans. trans-Urocanic acid (trans-UCA) is a major…”
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  20. 20

    The impact of solar ultraviolet radiation on human health in sub-Saharan Africa by Wright, Caradee Y, Norval, Mary, Summers, Beverley, Davids, Lester, Coetzee, Gerrie, Oriowo, Matthew O

    Published in South African journal of science (01-11-2012)
    “…Photoprotection messages and 'SunSmart' programmes exist mainly to prevent skin cancers and, more recently, to encourage adequate personal sun exposure to…”
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