Search Results - "NORVAL, Mary"
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The mechanisms and consequences of ultraviolet-induced immunosuppression
Published in Progress in biophysics and molecular biology (01-09-2006)“…Exposure to ultraviolet radiation (UVR) can result in immune suppression to antigens encountered within a few days of the irradiation. The process leading to…”
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More Than Effects in Skin: Ultraviolet Radiation-Induced Changes in Immune Cells in Human Blood
Published in Frontiers in immunology (10-06-2021)“…Cells of the skin and circulation are in constant two-way communication. Following exposure of humans to sunlight or to phototherapy, there are alterations in…”
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The challenges of UV-induced immunomodulation for children’s health
Published in Progress in biophysics and molecular biology (01-12-2011)“…Exposure to solar ultraviolet radiation (UVR) is recognised to have both beneficial and harmful effects on human health. With regard to immune responses, it…”
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The Consequences of UV-Induced Immunosuppression for Human Health
Published in Photochemistry and photobiology (01-09-2011)“…Exposure to UV radiation can cause suppression of specific immune responses. The pathways leading to the down‐regulation are complex, starting from the…”
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Solar ultraviolet radiation in a changing climate
Published in Nature climate change (28-05-2014)Get full text
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Urocanic Acid in the Skin: A Mixed Blessing?
Published in Journal of investigative dermatology (01-01-2011)“…Located in the stratum corneum, urocanic acid is a major epidermal chromophore for UVR. This simple molecule has attracted a great deal of research interest…”
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Vitamin D and solar ultraviolet radiation in the risk and treatment of tuberculosis
Published in The Lancet infectious diseases (2013)“…Summary Improved understanding of the association between tuberculosis and vitamin D is needed to inform clinical practice. Vitamin D has both…”
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Present and Future Impacts of Climate Change on Human Health in Sub-Saharan Africa
Published in Atmosphere (01-12-2020)“…The impacts of climate change on human health and wellbeing in sub-Saharan Africa are projected to increase in the near future and are of considerable concern…”
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Health Risks Associated With Excessive Exposure to Solar Ultraviolet Radiation Among Outdoor Workers in South Africa: An Overview
Published in Frontiers in public health (28-04-2021)“…Exposure of outdoor workers to high levels of solar ultraviolet radiation (UVR) poses significant, well-known health risks including skin cancer and eye…”
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The Effect of Chronic Ultraviolet Radiation on the Human Immune System
Published in Photochemistry and photobiology (01-01-2008)“…A single or a limited number of UVR exposures is recognized to suppress cell‐mediated immunity in human subjects. The complex pathway leading from the…”
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Recent advances in urocanic acid photochemistry, photobiology and photoimmunology
Published in Photochemical & photobiological sciences (01-06-2008)“…Urocanic acid (UCA), produced in the upper layers of mammalian skin, is a major absorber of ultraviolet radiation (UVR). Originally thought to be a 'natural…”
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Photoimmunosuppression: a brief overview
Published in Photodermatology, photoimmunology & photomedicine (01-04-2013)“…Summary Exposure to ultraviolet radiation can lead to suppression of many adaptive immune responses, both to antigens encountered within a short period of the…”
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Nitric oxide induces human CLA+CD25+Foxp3+ regulatory T cells with skin homing potential
Published in Journal of allergy and clinical immunology (01-11-2017)“…Capsule Summary Phototherapy releases nitric oxide and can reduce symptoms in Atopic Dermatitis (AD). Nitric oxide induced suppressive regulatory T cells and,…”
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The Incidence of Skin Cancer in Relation to Climate Change in South Africa
Published in Atmosphere (01-10-2019)“…Climate change is associated with shifts in global weather patterns, especially an increase in ambient temperature, and is deemed a formidable threat to human…”
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Cis-urocanic acid, a sunlight-induced immunosuppressive factor, activates immune suppression via the 5-HT2A receptor
Published in Proceedings of the National Academy of Sciences - PNAS (14-11-2006)“…Exposure to UV radiation induces skin cancer and suppresses the immune response. To induce immune suppression, the electromagnetic energy of UV radiation must…”
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Prostaglandin E2 imprints a long-lasting effect on dendritic cell progenitors in the bone marrow
Published in Journal of leukocyte biology (01-02-2014)“…Prostaglandin E2 attenuates systemic immune responses by modulating dendritic cell progenitors in the bone marrow. Dendritic cells (DCs) that differentiate in…”
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Effects of solar radiation on the human immune system
Published in Journal of photochemistry and photobiology. B, Biology (01-10-2001)“…On UV irradiation of the skin, a complex cascade of immunological changes results, initiated by cutaneous chromophores and ending in suppression of some local…”
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Characterization of regulatory dendritic cells differentiated from the bone marrow of UV‐irradiated mice
Published in Immunology (01-12-2013)“…Summary When antigen‐loaded dendritic cells (DCs) differentiated from the bone marrow (BM) of UV‐irradiated mice (UV‐BMDCs) were adoptively transferred into…”
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cis-Urocanic Acid Initiates Gene Transcription in Primary Human Keratinocytes
Published in The Journal of immunology (1950) (01-07-2008)“…It is well established that solar UV radiation (UVR) suppresses cutaneous cell-mediated immunity in humans. trans-Urocanic acid (trans-UCA) is a major…”
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The impact of solar ultraviolet radiation on human health in sub-Saharan Africa
Published in South African journal of science (01-11-2012)“…Photoprotection messages and 'SunSmart' programmes exist mainly to prevent skin cancers and, more recently, to encourage adequate personal sun exposure to…”
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