Search Results - "NORRIS, FANNY"
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Expression of protein-tyrosine phosphatases in the major insulin target tissues
Published in FEBS letters (06-10-1997)“…Protein-tyrosine phosphatases (PTPs) are key regulators of the insulin receptor signal transduction pathway. We have performed a detailed analysis of PTP…”
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Inhibitory Properties of Separate Recombinant Kunitz‐Type‐Protease‐Inhibitor Domains from Tissue‐Factor‐Pathway Inhibitor
Published in European journal of biochemistry (01-01-1996)“…Tissue‐factor‐pathway inhibitor (TFPT) is a multivalent inhibitor with three tandemly arranged Kunitz‐type‐protease‐inhibitor (KPI) domains. Previous studies…”
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Molecular cloning of the cDNA for a human amyloid precursor protein homolog: Evidence for a multigene family
Published in Biochemistry (Easton) (04-05-1993)“…Alzheimer's disease is a degenerative neurological disorder characterized by neural loss and brain lesions associated with plaques containing large amounts of…”
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Recombinant human extrinsic pathway inhibitor. Production, isolation, and characterization of its inhibitory activity on tissue factor-initiated coagulation reactions
Published in The Journal of biological chemistry (05-10-1990)“…Previous studies have shown that extrinsic pathway inhibitor (EPI) is an effective inhibitor of factor Xa alone or factor VIIa-tissue factor complex in the…”
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The 1.6 Å structure of Kunitz-type domain from the α3 chain of human type VI collagen
Published in Journal of molecular biology (1995)“…The C-terminal Kunitz-type domain from the α3 chain of human type VI collagen (C5), a single 58 amino acid residue chain with three disulfide bridges, was…”
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Purification and characterization of the trefoil peptide human spasmolytic polypeptide (hSP) produced in yeast
Published in FEBS letters (08-03-1993)“…Recombinant human spasmolytic polypeptide (r-hSP) has been produced in relatively large amounts in Saccharomyces cerevisiae. The two intronless trefoil domains…”
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Efficient site-directed mutagenesis by simultaneous use of two primers
Published in Nucleic acids research (11-08-1983)“…A rapid and efficient procedure for site specific mutagenesis is described. A double primed synthesis with a 17-mer mismatch primer and a “universal” 15-mer…”
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1.2 Å Refinement of the Kunitz-Type Domain from the α3 Chain of Human Type VI Collagen
Published in Acta crystallographica. Section D, Biological crystallography. (01-05-1998)“…The recombinant Kunitz‐type domain (C5) of human collagen α3(VI) chain was previously described at 1.6 Å resolution at room temperature. By changing the…”
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Expression, purification and characterization of a Kunitz-type protease inhibitor domain from human amyloid precursor protein homolog
Published in FEBS letters (24-01-1994)“…The Kunitz-type protease inhibitor domain from a recently identified homolog of the Alzheimer amyloid precursor protein (APPH KPI) was expressed in yeast,…”
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Molecular Cloning of Human Gastrin cDNA: Evidence for Evolution of Gastrin by Gene Duplication
Published in Proceedings of the National Academy of Sciences - PNAS (01-01-1983)“…An oligo(dT)-primed cDNA copy of the mRNA coding for the human gastrin precursor was constructed from poly(A)-containing RNA from a human pancreatic,…”
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Structure of a Human Gastrin Gene
Published in Proceedings of the National Academy of Sciences - PNAS (01-02-1984)“…A gastrin gene was isolated from a genomic library of human DNA. The human gastrin gene is about 4100 base pairs long and contains two intervening sequences…”
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